Instruction for Ketanov
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The drug is used for pain syndromes of various etiologies. Methods of use: oral and parenteral (intramuscular injection). Recommended for short term use.
Release form and composition
One coated tablet contains:
Active ingredient: Ketorolaka trometamol - 10,00 mg.
Excipients: corn starch - 44.76 mg, microcrystalline cellulose - 122.41 mg, colloidal silicon dioxide -1.83 mg, magnesium stearate - 1.00 mg.
Film coating: hypromellose - 2.91 mg, macrogol - 400 - 0.68 mg, purified talc - 0.16 mg, titanium dioxide -1.25 mg.
Round biconvex tablets, coated, white or almost white color with “KVT” engraving on <one side.
Pharmacological effect
The role of the active ingredient of the drug is Ketorolac, which has a pronounced analgesic, moderate antipyretic and anti-inflammatory effect.
Unlike narcotic analgesics, the use of Ketanov does not affect the psychomotor functions and the work of the heart muscle, does not inhibit the respiratory center and does not cause drug dependence.
The strength of the analgesic effect of Ketanov significantly exceeds other NSAIDs and is equivalent to morphine.
Indications for use
As a rule, elimination of the painful sensations of any location and nature is considered as the main indication for the use of Ketanov. In general, the following applications are considered:
elimination of pain from injuries, fractures, bruises;
elimination of pain after any surgical operations.
For a short time, Ketanov can relieve such conditions as:
Otitis;
Fibromyalgia (muscle pain);
Pain in osteoarthritis or osteoarthritis;
Pain in malignant tumors;
Sciatica (pain along the sciatic nerve);
Radicular syndrome;
Pain after discontinuation of narcotic analgesics;
Toothache for any dental diseases (for example, pulpitis, caries, periodontitis, etc.);
Pain during dental procedures;
Biliary or renal colic (in combination with antispasmodic drugs);
Pain after childbirth and episiotomy (perineal incision);
Osteochondrosis.
In case of sharp and sharp abdominal pains, it is not recommended to drink Ketanov, as this can hide conditions that should be surgically treated immediately.
Ketanov for toothache
When a toothache has appeared, do not immediately take pills. Try to thoroughly brush your teeth with a medical paste first, and then rinse your mouth with Rotokan every half hour. Effective with Metrogildenta toothache. If this does not help, and you cannot go to the dentist at the moment, you can use Ketanov.
You can drink a pill, or you can put it on a bad tooth - so you forget about the pain for 3-5 hours. When resuming it, take another 1 tablet, but no more. Do not abuse this medication, as it is a powerful analgesic, similar in properties to opium preparations. It also adversely affects the liver, and in combination with alcohol can lead to the failure of this organ.
Contraindications
Contraindications to the use of Ketanov are:
Treatment of chronic pain;
Simultaneous appointment with other NSAIDs;
Pregnancy, childbirth, breastfeeding period;
Children and adolescents under 16 years of age, since safety and efficacy have not been established;
Renal and / or hepatic impairment (with plasma creatinine levels above 50 mg / ml);
Anesthesia before or during surgery (due to an increased risk of bleeding);
Peptic ulcers, erosive and ulcerative lesions of the gastrointestinal tract in the acute stage, hypocoagulation (including hemophilia);
Hemorrhagic diathesis, hemorrhagic stroke (suspected or confirmed), impaired blood formation, high risk of recurrence or development of bleeding (including after operations);
Hypersensitivity to Ketorolac or other NSAIDs, angioneurotic edema, bronchospasm, aspirin asthma, dehydration and hypovolemia.
Ketanov are carefully prescribed to persons over 65 years of age and to patients with the following diseases:
Sepsis;
Active hepatitis;
Cholestasis;
Systemic lupus erythematosus;
Chronic heart failure;
Bronchial asthma;
Arterial hypertension;
Cholecystitis;
Impaired renal function (with plasma creatinine levels below 50 mg / ml);
Polyps of the nasopharynx and nasal mucosa.
Use during pregnancy and lactation
Ketanov in any form is contraindicated for use during pregnancy and lactation. Its use during pregnancy can only be used for health reasons from the mother. If Ketanov is indicated for a nursing mother, then for the period of its use a woman should transfer the child to artificial mixtures.
During childbirth, it is also impossible to use Ketanov for the purpose of anesthesia, since the drug lengthens the course of the childbirth and weakens the contractile activity of the uterus, which can trigger severe complications, including bleeding.
Women who are forced to use Ketanov during pregnancy should not worry too much, because in animal experiments there was no negative effect of the drug on the fetus. However, the females who received Ketanov had late childbirth and prolonged pregnancy.
Instructions for use
The instructions for use indicated that Ketanov in the form of tablets are taken orally.
A single dose for a single dose is 10 mg (1 tablet). If necessary, the drug in the same dose can be taken up to 4 times a day (maximum 40 mg per day).
Intramuscularly (deeply) Ketanov in the form of a solution for injection should be administered in the minimum effective doses that the doctor selects individually depending on the intensity of pain and the response to therapy. If necessary, simultaneous use with reduced doses of opioid analgesics is possible.
With a single intramuscular injection of single doses of Ketanov are:
Patients under 65 years of age - 10-30 mg (determined by the severity of pain);
Patients older than 65 years or patients with functional disorders of the kidneys - 10-15 mg.
With repeated intramuscular administration is usually used:
Patients under 65 years old - 10-30 mg, then every 4-6 hours, 10-30 mg;
Patients older than 65 years or patients with functional disorders of the kidneys - every 4-6 hours, 10-15 mg.
The maximum daily doses for intramuscular administration are:
Patients up to 65 years - 90 mg;
Patients older than 65 years or patients with renal impairment - 60 mg.
The same total daily doses should not be exceeded when switching from parenteral administration of Ketanov to taking the drug by mouth (on the day of the transfer, 30 mg of the drug is taken by mouth).
The duration of the use of Ketanov in any dosage form should not exceed 5 days.
Side effects
The use of Ketanov may cause the following side effects:
Central nervous system: often - drowsiness, dizziness and headache; rarely - hyperactivity (anxiety, mood changes), hallucinations, psychosis, depression, aseptic meningitis (severe headache, fever, stiff muscles of the back and / or neck, convulsions);
Urinary system: rarely - frequent urination, edema of renal genesis, nephritis, increase or decrease in urine volume, hemolytic uremic syndrome (hemolytic anemia, purpura, thrombocytopenia, renal failure,), back pain (including with hematuria and / or azotemia) acute renal failure;
The digestive system: often (especially in people over the age of 65, with a history of erosive and ulcerative lesions of the gastrointestinal tract) - diarrhea, gastralgia; less often - flatulence, feeling of fullness in the stomach, vomiting, constipation, stomatitis; rarely - erosive and ulcerative lesions of the gastrointestinal tract (including bleeding and / or perforation - burning or spasm in the epigastric region, abdominal pain, heartburn, nausea, coffee-like vomiting, melena, etc.), nausea, hepatitis, acute pancreatitis, cholestatic jaundice, hepatomegaly;
Cardiovascular system: less often - increase in blood pressure; rarely - fainting, pulmonary edema;
Sense organs: rarely - tinnitus, hearing loss and visual impairment (including blurred vision);
Hematopoiesis: rarely - eosinophilia, anemia, leukopenia;
Respiratory system: rarely - rhinitis, dyspnea or bronchospasm, laryngeal edema, manifested by shortness of breath and difficulty breathing;
Hemostasis system: rarely - nasal or rectal bleeding, bleeding from a postoperative wound;
Allergic reactions: rarely - anaphylaxis or anaphylactoid reactions (skin itching, rash, urticaria, discoloration of the skin, eyelid edema, shortness of breath, chest tightness, tachypnea or dyspnea, difficulty breathing, periorbital edema, wheezing);
Skin: less often - purpura, skin rash (including maculopapulla); rarely - urticaria, exfoliative dermatitis (fever, sometimes with chills, peeling, redness and / or hardening of the skin, soreness and / or swelling of the tonsils), Lyell and Stevens-Johnson syndromes;
Other: often - edema (feet, fingers, ankles, legs, face), weight gain; less often, excessive sweating; rarely fever, swelling of the tongue.
Overdose
Overdose symptoms: nausea, vomiting, abdominal pain, the formation of peptic gastric ulcers, erosive gastritis, metabolic acidosis, impaired renal function.
Treatment: gastric lavage, the appointment of adsorbents and symptomatic therapy.
special instructions
In the postoperative period, the drug Ketanov should be used with caution, while controlling the clotting ability of the blood. This is due to the high risk of bleeding in the postoperative period.
The drug is used with particular caution in patients with depression of liver function and impaired cardiac activity. Patients with erosive gastritis or gastric ulcer in a history of treatment of drugs can only be carried out with the permission of a specialist after a preliminary examination.
Since hypersensitive patients may complain of dizziness, headaches and drowsiness during use, you should avoid driving a car and controlling complex mechanisms that require high concentration of attention.
Drug interactions
With the simultaneous use of Ketorolak with other NSAIDs, additive side effects may develop; with pentoxifylline, anticoagulants (including low-dose heparin) - may increase the risk of bleeding; with ACE inhibitors - may increase the risk of developing renal dysfunction; with probenecid - plasma ketorolac concentration and its half-life increase; with lithium preparations - a decrease in the renal clearance of lithium and an increase in its plasma concentration is possible; with furosemide - reducing its diuretic action.
With the use of Ketorolac, the need for the use of opioid analgesics for pain relief is reduced.
Compatibility with alcohol
This drug is incompatible with alcohol, because it increases the risk of side effects from the gastrointestinal tract in the form of gastralgia, abdominal pain and bleeding from the gastrointestinal tract. Alcohol enhances the analgesic effect, so you can skip that moment when you need to see a doctor immediately. In addition, enhances the inhibitory effect on the central nervous system, causing drowsiness, lethargy.
Reviews
We picked up some feedback from people about Ketanov:
Lera
A good drug, saves the whole family from back pain, teeth and head. Acts immediately and for a long time. You can safely forget about pain for the whole day. Fully satisfied with the action of the drug and its affordable price. It’s bad that in pharmacies without a doctor’s prescription you don’t get it, and by that time doctors are not in a hurry to write prescriptions, unfortunately, you have to come back and defend a living line all over again. In general, of course, there are no complaints about the drug and its action, it saves at the right moment. And, importantly, it has analogues lower in cost, which can be purchased without a doctor's prescription, having a lower cost and no less effective.
Masha
Six months ago, put braces. The first five days, my teeth ached unbearably. Many people recommended to drink “Nimesil”, but it does not help me, but “Ketanov” just saved me. I always carry a “Ketanov” plate in my beautician, because I cannot tolerate a toothache, but he quickly acts and has a long lasting effect from the pill. And there was a case that a headache was very painful and there was nothing with itself except “Ketanov”. So I drank it and it helped.
Kseniya
I have a very painful first day during my periods. I tried a lot of different painkillers including a pain and tempalgin. I didn’t help, the pain didn’t go away. I read about Ketanov on the Internet, now I don’t know another pain medicine !! If I know that today menstruation I immediately drink a pill and I forget about the pain in general)))) Yesterday, while at home let me think, I don’t drink, all the same I also got hooked on Ketanov. Forget, Right now I die !!)))) At night I couldn’t suffer from the pain already reducing everything ... got up and drank and how many hours later An hour all back to normal, God, thank you who esko created, I think I'm not the only one who thinks so !!! )))
Storage conditions
Keep tablets away from small children at room temperature. The shelf life of the tablets is indicated on the package, at the end of which the drug cannot be taken orally.
Terms of sell
You can buy Ketanov without a prescription.