Ketofril tabs 10mg #20

Instructoin for Ketofril

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Pain accompanies a person for life. All over the world, people are injured, suffer from rheumatic and dental pain.
Migraines, women's ailments, infections, arthrosis are always accompanied by pain.
Without an effective adequate painkiller, the subtle and tender nature of man is destroyed morally, physically and psychologically.
And the first thing that the doctor who is treating us helps is to prescribe a remedy for pain relief, inflammation and temperature relief.
The most effective way to relieve pain of any origin is Ketofril.
The international name of the drug - Ketorolac.

Pharmacological properties of ketofril

Ketofril belongs to the group of nonsteroidal anti-inflammatory drugs. It has the property of suppressing platelet aggregation, retards the synthesis of prostaglandins, which affect the body's thermoregulation, inflammation and pain.
The drug is not addictive. The effect of the relief of pain occurs within an hour, maximum analgesia occurs two hours after the injection. Ketofril is absorbed by absorption through the digestive system, concentrated in the blood plasma for 40 minutes.
Eating fatty foods contributes to the accumulation and retention of the drug in the blood. About half of the active substance is metabolized in the liver. The main percentage of the substance is excreted by the kidneys, a small percentage of the gastrointestinal tract.
The half-life process takes an average of five to ten hours. The half-life depends on the age group of the patient, chronic diseases, kidney problems.

Release form and composition

For intravenous and intramuscular administration, 1 ml of the substance is produced in ampoules. Ampoules are packed in plastic cells. The carton contains 5 or 10 ampoules with instructions.
The composition of Ketofril for injection includes: ketorolac trometamol (ketorolac tromethamine), sodium chloride, disodium edetate, ethanol, sodium hydroxide, distilled water.
In addition to injections, Ketofril is available in tablets for pre-oral administration, in the form of a gel for external application and eye drops.

Indications for use

Ketofril has a strong analgesic effect, comparable in effect to relieving pain with morphine. It relieves pain of varying intensity and of any origin, including cancer.
In case of injuries of a traumatological nature: dislocations, fractures, ruptures of the ligaments and tendons. With dental interventions, dental, neuralgic and musculoskeletal pains.

Dosing and timing of administration

    the age category of patients up to 65 years of age, the dose of injection is prescribed at a maximum of 30 mg with an injection interval of four to six hours (120-180 mg per day);
    after the age of 65, it is indicated to use no more than 30-60 mg per day;
    for thin people weighing up to 50 kg, the permissible dose of 90 mg per day;
    patients with acute and chronic diseases of the kidneys and liver, with a history of hepatic and renal insufficiency, the recommended dose does not exceed 15 mg of the drug per day.
With urgent need, perhaps a single injection of ketofril. The maximum allowable number of days for injections is up to two days. With continuous medical observation and the severity of the disease, the course of treatment is extended to five days.

The body's response to taking Ketofril with other remedies

    a single dose with aspirin, calcium-containing drugs, analgesics and nonsteroidal anti-inflammatory drugs provokes the occurrence of bleeding and ulceration in the intestinal tract.
    Toxic to the liver and kidneys, while used with methotrexate or paracetamol;
    co-administration with probenecid affects the distribution and the half-life of Ketofril;
    anticoagulants, thrombolytics, heparin provoke the occurrence of bleeding;
    the combination of ketofril with diuretics and antihypertensives reduces their effectiveness;
    there is a pharmaceutical incompatibility of the active substance Ketofril with a solution of tramadol and lithium-containing agents.

Adverse events

From the digestive organs
upset stomach, constipation, epigastric heaviness, nausea, heartburn. Rarely - inflammation of hepatitis, pancreatitis, erosion and stomach ulcers
Urinary system
renal failure, delay or frequent urination, nephritis, edema
Auditory and visual organs
hearing loss, blurred vision, tinnitus
Respiratory system
choking, swelling in the larynx, rhinitis
Sensitivity of the nervous system
headaches and dizziness, lethargy, drowsiness, convulsions, numbness of the extremities, irritability
The cardiovascular system
high blood pressure, possible fainting
Blood formation systems
anemia, leukopenia
Hemostasis
rectal and nasal bleeding
Dermatology
redness and peeling of the skin
Allergic reactions
skin rash in the form of urticaria, itching, eyelid edema
Spot local reactions
pain and burning at the injection site
Rare manifestations
swelling of the limbs, excessive sweating, weight gain

Overdose

The reaction of the body in overdose is similar to side effects. Treatment is carried out according to the symptoms with the appointment of drugs that support the functions of the body.

Contraindicated to the appointment

The drug is not prescribed in the presence of:
    hypersensitivity to the components in the composition of Ketofril;
    presence of bronchodilator spasms;
    intolerance to acetylsalicylic acid;
    edema of various origins;
    internal bleeding, hemophilia, disorders of the hematopoietic system;
    peptic ulcer, erosion of the stomach and duodenum;
    chronic diseases of the kidneys and liver in acute form;
    hyperkalemia;
    cerebral hemorrhage;
    hemorrhagic diathesis;
    simultaneous use with anti-inflammatory and analgesic agents;
    in the postoperative period at risk of bleeding;
    after shunting of the aorta;
    all term of pregnancy, during labor and feeding;
    children's age category and adolescence.
Use caution: elderly patients, in the presence of asthma, coronary artery disease, high blood pressure, diabetes, systemic diseases of the immune system, polypous formations of the mucous membranes.
Reception at pregnancy, breastfeeding, at children's age
During the entire gestation period, during labor and breastfeeding, Ketofril is prohibited. The drug affects the blood circulation of the fetus, inhibits the reduction of the uterus, affects the labor activity.
Not appointed in childhood and adolescence. After 16 years, prescribed with caution and with urgent need.

Special instructions

Do not drink alcohol during the course of injections. Smoking is not desirable.
Older people of age category of treatment is carried out under the supervision of the attending physician. It is forbidden to use for pregnant women, nursing mothers, children.
In order to avoid the risk of undesirable manifestations in the application of ketofril, it is necessary to strictly observe the recommended dosage with a minimum short course of administration.
It does not recommend classes that require attention and speed of reaction, driving and precise mechanics.
The drug causes drowsiness, dizziness, slow response.

Terms of storage

Store in original packaging in a dry place, away from sunlight. Permissible storage temperature up to 30 degrees. Keep away from children and animals. Validity of the drug for two years from the date of manufacture. After the expiration of the storage period is recyclable.

Reviews

Judging by the reviews, with unbearable pains, taking the drug relieves pain and greatly alleviates the condition. It is necessary to consider side effects and individual reactions to the drug. Many patients had stomach pain, nausea, and dizziness.
According to the reviews of doctors, a positive effect of pain relief was noted and short-term use of Ketofril was recommended.
If you have experience in taking Ketofril, we would be grateful for your feedback and opinion about the drug. Your feedback will be useful information for site visitors.

Conclusion

    Ketofril is a nonsteroidal anti-inflammatory drug.
    The active substance is ketorolac trometamol.
    The effect of the drug to eliminate pain is comparable to the effect of morphine.
    Assign to relieve pain with injuries of a traumatic nature.
    Since there is a large list of adverse reactions, the drug is not prescribed in children and pregnant women.

Terms of sell

You don't need a prescription to buy Ketofril.