Cosopt drops 20mg + 5mg/ml 5ml

Instruction for Cosopt

You can buy Cosopt eye drops on this page

Drug form, composition

The therapeutic effect of Cosopt drops is due to the two active substances that make up the composition. These include:
    dorzolamide hydrochloride;
    timolol maleate.
Auxiliary components are represented by the following components:
    benzalkonium chloride;
    sodium citrate (preservative E331);
    polyethylene glycol (PEG);
    sodium hydroxide (caustic soda);
    mannitol;
    purified water.
The medication is released in the form of a slightly viscous solution, colorless and odorless. Drops are produced in 5 ml plastic bottles of the Okumeter Plus type. The branded cardboard box contains one bottle of medicine and an annotation with all the characteristics of the drug.
The drug is produced by the French pharmaceutical company Merck Sharp & Dohme.

Mechanism of action

Cosopt ophthalmic drops belong to the group of antiglaucoma combined medicines for local use. The ability of a medicinal solution to reduce intraocular pressure is based on the action of two active ingredients:
    Timolol is a non-selective beta-blocker with intrinsic sympathomimetic and membrane-stabilizing activity. When applied topically, timolol reduces both increased intraocular pressure and normal pressure. A decrease in IOP indicators is achieved by inhibiting the formation of eye fluid and increasing its excretion.
    Dorzolamide is a carbonic anhydrase inhibitor. This antiglaucoma agent helps to reduce the formation of bicarbonate ions with the subsequent slowing down of sodium and fluid transport. As a result, the secretion of intraocular fluid decreases.
The antihypertensive effect of drops occurs 20 minutes after instillation, reaching a peak of activity after 120 minutes. The therapeutic effect lasts for a day. After instillation, both active components enter the systemic circulation. Excreted mainly by the kidneys along with urine.

Indications, contraindications

The medication is intended to reduce IOP. Pseudoexfoliative glaucoma and open-angle glaucoma are the main indications for the appointment of Cosopt eye drops.
The drug has a fairly wide list of absolute contraindications. The drug should not be used if the patient has the following pathologies and conditions:
    susceptibility to at least one component of the drug;
    atrioventricular heart block 2-3 degrees of severity;
    chronic obstructive pulmonary disease in the acute phase;
    decreased heart rate (sinus bradycardia);
    deterioration of myocardial contractility;
    bronchial hyperreactivity syndrome;
    acute heart and kidney failure;
    extreme degree of left ventricular failure (cardiogenic shock);
    bronchial asthma;
    diseases accompanied by corneal dystrophy;
    period of bearing a child;
    lactation period;
    children under 18 years of age.
Diabetes mellitus, corneal changes, thyrotoxicosis, the process of cardiac conduction disorders of the 1st degree, circulatory disorders, urolithiasis, old age are relative contraindications, in which eye drops are prescribed carefully. Such patients require constant monitoring by an ophthalmologist.

Instruction (method, dosage)

As a rule, ophthalmologists recommend the standard dosage regimen indicated in the instructions. Adults and children over 18 years of age are prescribed 1 drop in each conjunctivitis sac 2 times a day. The first instillation should be carried out in the morning before 10 o'clock, the second - in the evening, before bedtime.
Before instillation, wash hands thoroughly with soap. Then, in a sitting position, the head is slightly thrown back, the lower eyelid is pulled back with a finger. Instillation is performed. For even distribution of the medicinal solution after the procedure, it is recommended to blink intensively for several seconds.

Side effects, overdose

Adverse reactions during treatment with Cosopt drops are very rare. The most common side effects are due to excess dosage. First of all, changes are manifested on the part of the organ of vision. Patients complain of watery eyes, blurred vision, itching and burning in the eyes. Nausea, vomiting, epistaxis, headache, dizziness, shortness of breath, heart palpitations are possible systemic side effects.
Overdose with topical application is unlikely. If a large amount of the medicinal solution gets into the eyes unintentionally, they should be rinsed with plenty of water. If necessary, consult a doctor.

Special instructions

Important information that must be read before using Cosopt drops:
    Use drops should be discontinued 2 days before the operation with general anesthesia. Timolol is able to enhance the effect of pain medications.
    Instillation should be carried out carefully, without touching the mucous membrane and other surfaces with the dropper. After the procedure, the vial with the medicine is tightly closed and placed in the original cardboard box.
    The drug is not recommended for patients with angle-closure glaucoma. For this pathology, another therapy is performed.
    Prolonged use of Cosopt drops can lead to an addiction of the body to the active substances. As a result, the therapeutic effect can be significantly reduced.
    Benzalkonium chloride (in droplets) can negatively affect the contact device. It is recommended to stop wearing any contact lenses during treatment.
    After instillation, temporary blurred vision is possible. Therefore, you can get behind the wheel of a car and engage in potentially hazardous activities 30 minutes after the procedure.
    It is necessary to cancel the medication carefully, by gradually reducing the daily dosage.
    Cosopt's components do not adversely affect the functioning of the brain and other structures of the central nervous system.
If a heart disease has been previously transferred, then patients should be under the supervision of doctors in order to provide emergency measures in the event of exacerbations of the underlying disease.

Interaction with other medications

It is not recommended to simultaneously use Cosopt drops with the following groups of medicines:
    calcium channel blockers;
    systemic carbonic anhydrase inhibitors;
    parasympathomimetics;
    opioid analgesics;
    antiarrhythmic drugs;
    beta-blockers;
    isoenzyme inhibitors;
    monoamine oxidase inhibitors;
    catecholamine-depleting drugs;
    digitalis glycosides;
    salicylates;
    antidiabetic agents.
The patient should be sure to warn the attending physician about taking medications from this list.

Storage conditions

Shelf life - 2 years from the date of production by the pharmaceutical company. After opening, the medicinal solution is suitable for use within a month. The bottle is disposed of even if there is any medicine left in it. It is forbidden to use drops after the expiration date.
Store the drug in a place protected from sunlight and children. Room temperature is optimal storage conditions.

Reviews

Gennady, 36 years old
After a concussion, my intraocular pressure sometimes rises. The treatment was almost over, but my eyes got worse. The doctor prescribed Cosopt eye drops for me. Indeed, IOP gradually returned to normal. I finished the treatment a month ago, and the intraocular pressure has never bothered me yet. I recommend!
Elena Petrovna, 56 years old
About a month ago, she was diagnosed with open-angle glaucoma. The doctor immediately prescribed these drops and started treatment. I use them now, I have not found any side effects, but the intraocular pressure has noticeably decreased. The only negative for me is the high price.

Terms of sell

You don't need a prescription to buy Cosopt.