Enzystal-P tabs #20

Instruction for Enzystal-P

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Enzystal-P is a drug containing enzymes (digestive enzymes) that help improve the digestion process.

Release form and composition

Enzystal-P is produced in the form of enteric-coated tablets: biconvex, round, pink (10 pcs. In blisters; in a cardboard box 1, 2, 4 or 8 blisters).
1 tablet contains:
    active substance: pancreatin - 116.17 mg [with a minimum enzymatic activity of 250 units of protease. Ph. Eur. (Units of action of the European Pharmacopoeia), lipase 3500 UNITS. Ph. Eur., Amylase 4200 U Ph. Eur.];
    additional components: microcrystalline cellulose, colloidal silicon dioxide, lactose monohydrate, magnesium stearate, sodium carboxymethyl starch;
    enteric coating: diethyl phthalate, macrogol 6000, cellulose acetate phthalate, azorubin (carmoisin), white beeswax, titanium dioxide, hypromellose.

Pharmacodynamics

Enzystal-P is a digestive enzyme preparation that replenishes the deficiency of pancreatic enzymes and has amylolytic, proteolytic and lipolytic effects. The pancreatic enzymes included in the composition of the product, such as alpha-amylase, lipase, chymotrypsin, trypsin, are involved in the breakdown of fats to fatty acids and glycerol, proteins to amino acids, starch to monosaccharides and dextrins. The active substance Enzystal-P contributes to the normalization of digestion processes, improvement of the functional state of the gastrointestinal tract (GIT), provides complete and rapid digestion of food, reduces the severity of symptoms resulting from digestive disorders (feeling of fullness and heaviness in the stomach, diarrhea, flatulence). Trypsin contained in pancreatin inhibits the stimulated secretion of the pancreas, exhibiting an analgesic effect. From the dosage form, pancreatic enzymes are released in the small intestine (under the influence of its alkaline environment), since the tablets are coated with a coating that protects against the action of gastric juice.

Indications for use

    exocrine pancreatic insufficiency (as a means of replacement therapy): chronic pancreatitis, flatulence, dyspepsia, non-infectious diarrhea, cystic fibrosis, pancreatectomy, condition after radiation;
    conditions after resection of the stomach and small intestine, accompanied by impaired absorption of food;
    Remheld syndrome (gastrocardiac syndrome);
    prolonged immobilization, a sedentary lifestyle, impaired chewing function (to improve food digestion);
    the presence of inaccuracies in nutrition in persons with normal gastrointestinal tract function - irregular nutrition, consumption of large amounts of food or hard-to-digest, fatty foods.
According to the instructions, Enzystal-P is also recommended for use in preparation for X-ray and ultrasound examination (US) of the abdominal organs.

Contraindications

    age up to 3 years;
    acute pancreatitis;
    stage of exacerbation of chronic pancreatitis;
    hypersensitivity to the components of the drug.

Instructions for use, method and dosage

Enzystal-P is taken orally. Simultaneously with a meal or immediately after a meal, the tablets are swallowed whole without chewing and washed down with plenty of liquid.
The recommended average dose for adults is 1-2 tablets. Taking into account the degree of pancreatic insufficiency and the quantity / quality of food consumed, if necessary, it is allowed to increase the dose to 2–4 tablets. Doses in excess of 4 tablets may only be taken as directed by your doctor. The maximum daily dose of lipase should not be more than 15-20 thousand units / kg.
For children, the dosage regimen is established by the doctor, in most cases it is recommended to take 1 tablet of Enzystal-P 3 times a day with meals.
The duration of treatment is determined individually. In case of digestive disorders due to an error in the diet, the course can be several days, with replacement therapy - from several months to several years.

Side effects

While taking Enzystal-P, the development of allergic reactions was sometimes observed, in rare cases, the appearance of nausea, diarrhea / constipation, and discomfort in the epigastric region was noted.
With prolonged use of the drug in high doses, the occurrence of such a side effect as hyperuricosuria was recorded, and when high doses are taken, patients with cystic fibrosis develop strictures in the ascending colon and in the ileocecal region.

Overdose

Symptoms of an overdose of Enzystal-P may include hyperuricemia and hyperuricosuria, in children - constipation.
If an overdose is suspected, it is necessary to stop taking the drug and conduct symptomatic therapy.

Special instructions

Application during pregnancy and lactation

During pregnancy and lactation, the enzyme is used only when the expected benefit of the treatment to the mother outweighs the possible threat to the health of the fetus or baby.

Pediatric use

In pediatrics, Enzystal-P is contraindicated in children under 3 years of age.

Drug interactions

With the combined reception of Enzystal-P with iron preparations, there may be a decrease in the absorption of the latter.

Terms and conditions of storage

Keep out of the reach of children at a temperature not exceeding 25 ° C.
The shelf life is 3 years.

Reviews

According to reviews, Enzystal-P is an effective drug used for digestive problems. Patients who took the enzyme agent note a rapid relief of symptoms caused by impaired absorption of food, as well as the normalization of digestion processes.
There are no reports of the development of side effects.

Terms of sell

You can buy Enzystal-P without a prescription.