Taflotan drops 0.0015% 0.3ml #30

Instruction for use of Taflotan

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Dosage form, composition

Drops for eyes Taflotan released in the form of a clear medicinal solution, colorless and odorless. The substance tafluprost acts as an active component of the drug. Additional ingredients:
    disodium edetate;
    sodium dihydrogen phosphate;
    Surfactant - polysorbate 80;
    glycerol;
    purified water.
To obtain the required pH, hydrochloric acid and / or sodium hydroxide are added to the solution.
The ophthalmic solution is packaged in 0.3 ml dropper tubes. One branded pack contains 3 or 9 sealed packs of 10 tubes, packed in an aluminum foil bag. Each carton pack contains instructions with a description of the drug. The eye drops are produced by a pharmaceutical company from Finland - Santen OY.

Therapeutic action

Eye drops Taflotan - antiglaucoma drug. The therapeutic effect is provided by the active substance, which is a fluorinated analogue of prostaglandin F2α. Possesses selective activity against receptors from the group of prostaglandins. In the course of the study, it was found that the decrease in IOP occurs due to the stimulation of the uveoscleral outflow of aqueous humor. But there is also an improvement in blood flow in the optic nerve head.
Decrease in intraocular pressure after instillation occurs gradually, after about 2-4 hours. The maximum effect is recorded after 12 hours. The therapeutic effect lasts a day. Systemic absorption is negligible. 10 minutes after instillation, the maximum concentration of the drug in the blood plasma is detected, and it decreases within an hour. Most of it is excreted by the kidneys along with urine, the rest - with feces.

Indications and contraindications for use

Open-angle glaucoma, ophthalmic hypertension are the main indications for the appointment of Taflotan drops. The drug is used in mono therapy under the following conditions:
    lack of effect while taking first-line drugs;
    individual intolerance or direct contraindications to first-line drugs;
    sensitivity to other ophthalmic drops, which contain preservatives (for example, benzalkonium chloride).
Taflotan is prescribed in complex therapy, combining with drugs that block beta-adrenergic receptors in the human body (beta-blockers).
Use in special categories of patients:
    Application in children. There is no reliable information on the use of the drug in children under 18 years of age.
    Use in pregnant and lactating women. Taflotan may have adverse pharmacological effects on pregnancy and on the fetus. The drug is prescribed when there are no other therapy options. It is not recommended to use during lactation, as the constituent drops can pass into breast milk.
    Use in the elderly. Elderly patients do not require adjustment of the dosage regimen of the drug.
    Application for impaired renal and liver function. Care should be taken to carry out therapy in patients with insufficient functioning of these organs. The effectiveness and safety of the active substance in this case is poorly understood.
Individual intolerance to at least one component of the medication is a direct contraindication to use.

Dosing regimen, method of administration

The instructions for Taflotan drops indicate the recommended dose - 1 drop in each conjunctivitis sac 1 time per day. Preferably, instillation is carried out in the evening. It is necessary to bury the solution strictly 1 time per day. Otherwise, the therapeutic effect of the drops worsens, that is, the decrease in IOP is less effective. The duration of therapy is determined by the attending physician on an individual basis.
Instillation is carried out while sitting, with the head thrown back slightly. The lower eyelid is pulled back, instillation is performed. The procedure is repeated with the second eye. To distribute the drops evenly, close your eyes for a few seconds. To reduce the risk of darkening of the eyelids, it is recommended to wipe off excess drops from the skin with a cotton pad after instillation. Light pressure on the nasolacrimal duct after instillation will help reduce absorption.

Side effects, overdose

Conjunctival hyperemia (redness of the eye mucosa) is the most common side effect that occurs during treatment with Taflotan drops. In most cases, the hyperemia is moderate, therefore it does not require discontinuation of the drug.
On the part of the organ of vision, the following undesirable consequences may occur:
    pain, itching and burning in the eyes;
    foreign body sensation;
    decreased vision (blurred);
    dry eye syndrome;
    lacrimation;
    swelling of the eyelids and conjunctiva;
    increased growth of eyelashes (change in their thickness, length);
    intense pigmentation of the iris;
    punctate keratitis;
    allergic conjunctivitis, blepharitis (rare).
Headache, dizziness, nausea, worsening asthma are other possible side effects. If the dosage is exceeded many times, some patients experience significant damage to the cornea.
Overdose cases were not registered. If a large number of drops accidentally get into the eyes, they should be rinsed with plenty of clean water.

Special instructions, interaction

Before you start using Taflotan eye drops, you must read the following important recommendations:
    During the treatment period, a change in the appearance of the organ of vision (intense pigmentation of the iris, excessive growth of eyelashes, discoloration of the eyelids) is possible.
    The dropper bottle is intended for single instillation only. After the procedure, it must be disposed of, even if there is still some solution left inside.
    If the doctor has prescribed several ophthalmic agents for topical use, it is necessary to maintain an interval between their use of at least 15 minutes.
    The drug is used with caution in angle-closure, congenital, narrow-angle or neovascular glaucoma. There is no experience of using drops to treat this category of patients.
    The components of the drug have no effect on the brain and structures of the central nervous system.
    After instillation, a temporary deterioration in vision is possible, which must be taken into account when doing potentially dangerous work and driving a car.
    Women of childbearing age are recommended to use Taflotan only in case of reliable contraception.
A clinically significant interaction of the active compound of the eye drops with medicines of other pharmacological groups has not been established.

Additional Information

Taflotan eye drops are dispensed from pharmacies strictly according to a medical prescription. The shelf life is 3 years from the date of manufacture. Violation of the packaging is not allowed. The optimal storage temperature is 2-8 ° C. The shelf life after the first opening of the foil bag is 4 weeks.
After opening the foil bag, where the plate with dropper bottles is located, store at a temperature not exceeding 25 ° C. The opened tube is intended for single use only. After instillation, it must be disposed of. The access of children and pets to the medication is necessarily limited.

Reviews

Anna Borisovna, 59 years old
For me personally, these drops, although they relieve eye pressure, cause discomfort and a feeling of a foreign body in the eyes. Despite this, the doctor does not cancel them for me. He said that it happens. And the most annoying thing is that the drops can change your eye color. Especially it is necessary to think about those who drip into one eye only. The most important advantage is that the drops effectively reduce even very high intraocular pressure. I continue my treatment.
Ekaterina Sergeevna, 56 years old
After the application of Taflotan, intraocular pressure decreased significantly. I noticed that my eyelashes darkened slightly after the end of the full treatment course. The state of health with the use of the drug remained normal, no side effects were observed. I have an extremely positive impression of Taflotan. In my opinion, the only drawback of the drug is its relatively high cost.
Sergey Viktorovich, 45 years old
Glaucoma 5 years. Various drugs were used (by selection from a doctor). Poor portability. Now (for the last three months) I have been using Taflotan drops without preservatives, in disposable containers. The effect is good, the side effects are minimal. The only thing that is annoying is the high price tag of the medicine. The attending physician refuses to prescribe other drops, because believes that Taflotan is the best antiglaucoma remedy.

Terms of sell

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