Oftan Dexamethasone drops 0.1% 5ml

Instruction for Oftan Dexamethasone

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Composition, form and packaging of the medicine

Oftan Dexamethasone is a clear liquid without a pronounced odor and color. Dexamethasone in the form of dexamethasone sodium phosphate is the active ingredient. Additionally, the composition includes several ingredients:
    sodium tetraborate;
    benzalkonium chloride;
    orthoboric acid;
    calcium sodium EDTA;
    injection water.
The drug solution is packaged in 5 ml polypropylene vials with a built-in dropper for more accurate dosing. The bottle is in an original sealed cardboard box. It is accompanied by a leaflet with a detailed description of the medicine and instructions for use. Oftan Dexamethasone is manufactured by the pharmaceutical company Santen from Finland.

Medicinal qualities

Oftan Dexamethasone eye drops belong to the group of topical glucocorticosteroids. Dexamethasone is a synthetic substance that provides a powerful anti-inflammatory and anti-allergic effect, which is achieved through:
    stabilization of lysosomal enzymes of leukocyte membranes;
    inhibiting the release of enzymes;
    obstacles to kininin synthesis;
    inhibition of leukocyte migration;
    violations of antigen recognition;
    suppression of antibody synthesis.
All these properties are simultaneously involved in suppressing the inflammatory response in the affected tissues. After applying the drops, the therapeutic effect lasts for 4-8 hours.
When applied topically, the constituent drugs practically do not penetrate into the systemic circulation. At the same time, they penetrate well into the conjunctiva and corneal epithelium, which endows the drops with high bioavailability (more than 75%). The drug is excreted from the body in a modified form through the intestines.

Indications for appointment

Acute and chronic inflammatory processes of the organ of vision are the main indications for use indicated in the instructions. These include:
    conjunctivitis (allergic, non-purulent) - an inflammatory lesion of the conjunctiva;
    keratitis - inflammation of the cornea of ​​the eyes;
    blepharitis - inflammation of the edges of the eyelids;
    scleritis - an inflammatory process that takes place in the tissues of the sclera and deeply affects the episcleral vessels;
    keratoconjunctivitis - inflammation that affects the conjunctiva and cornea at the same time;
    blepharoconjunctivitis - inflammation of the edges of the eyelids in combination with damage to the palpebral and orbital conjunctiva;
    episcleritis - an inflammatory disease affecting episcleral tissue lying between the conjunctiva isclera;
    iritis - inflammation of the iris of the eyes;
    retinitis - inflammation of the retina;
    uveitis - intraocular inflammation, involving the choroid in the process;
    iridocyclitis (anterior uveitis) - inflammation of the iris and the ciliary body of the eyeball.
Optic neuritis, retrobulbar neuritis, superficial corneal injuries of various etiologies are conditions in which Oftan Dexamethasone eye drops are also indicated. Also, the medication is indicated for therapeutic and prophylactic purposes for inflammatory phenomena in the period after injuries and surgical interventions. In ENT practice, this eye remedy is sometimes prescribed for otitis media.

Contraindications

Since the drug contains a powerful corticosteroid, it is not prescribed in many cases. The main contraindications include:
    increased intraocular pressure;
    various forms of glaucoma;
    viral pathologies of the conjunctiva, cornea;
    bacterial and fungal damage to the organ of vision;
    acute purulent eye pathologies;
    keratitis caused by herpes simplex (Herpes simplex);
    tuberculosis of the eyes;
    chicken pox;
    high level of sensitivity to any component of the solution.
Due to the lack of data on the efficacy and safety of the use of Oftan Dexamethasone for the treatment of children and adolescents under 18 years of age, the drug is not prescribed for this category of patients. For pregnant and lactating women, drops are prescribed after assessing the possible benefits and risks.

Method of administration, doses

Oftan Dexamethasone eye drops are intended only for topical use, it is strictly forbidden to use them inside. Standard dosage for inflammatory processes:
    1-2 drops into the affected eye every 1-2 hours in the acute period (the initial stage of pathology);
    1-2 drops up to 3-5 times a day as the condition improves.
The duration of treatment is 14-21 days. Only the attending physician can extend the course after evaluating the effectiveness of the therapy.

Side effects, overdose

First of all, undesirable consequences manifest themselves on the part of the organ of vision. A person may be worried about:
    itching and burning sensation in the eyes;
    allergic reactions;
    corneal opacity, pronouncement, perforation;
With prolonged use, lens opacity, increased intraocular pressure, the development of steroid cataracts and secondary glaucoma are possible.
When used correctly, overdose is unlikely. When it occurs, it manifests itself in the form of local symptoms. There is no specific antidote. The medication should be canceled, symptomatic therapy should be selected.

Precautionary measures

Oftan Dexamethasone should not be used concomitantly with quinidine and erythromycin. Drops reduce the effectiveness of drugs that block calcium channels. Additional instructions:
    The duration of therapy for the treatment of pregnant and lactating women should not exceed 10 days.
    It is not recommended to instill a double dose of drops if the previous instillation is missed.
    If no improvement is observed within 3-5 days, you should consult a doctor. Perhaps the drug was chosen incorrectly.
    Contact lenses must be removed before instillation. You can put on the ophthalmic device after 20-30 minutes. Many doctors recommend wearing glasses during therapy.
    If treatment lasts more than 14 days, intraocular pressure monitoring is required.
Due to possible lacrimation and temporary blurred vision after instillation, drops are not recommended to be used immediately before driving or operating mechanical equipment.

Additional Information

The shelf life of the sealed bottle is 2 years, after opening the medicinal solution is suitable for treatment within a month. Store the bottle in its original packaging at 2-8 ° C in the refrigerator. The access of children and pets to the medicine is necessarily limited.

Reviews

Maria Sergeevna, 46 years old
Oftan Dexamethasone - serious drops with high efficiency. Prescribed them to me when other means did not remove inflammation with advanced conjunctivitis. First, Lekrolin was prescribed, which not only did not cope with the inflammation, but also intensified it. Improvement from Oftan Dexamethasone came after 2 days. The eyes stopped itching, blushing. The disease gradually receded. The entire treatment lasted 2 weeks. I recommend these drops, but only after consulting a doctor, because the drug is hormonal.
Lilia, 35 years old
Last year, I did laser correction, eye drops were prescribed, which caused terrible redness and inflammation. The doctor prescribed Oftan Dexamethasone. As it turned out, the drug is very strong, with a hormone in its composition. They warned that in no case should the dosage be exceeded, otherwise there would be side reactions. She was treated strictly following all the instructions of the ophthalmologist. When applied, only a slight burning sensation occurred, which passed on its own. The unpleasant symptoms completely disappeared after 5 days. Wonderful droplets at an affordable price, I recommend!
Vladimir, 46 years old
I work as a welder, sometimes I neglect safety rules. Therefore, it happens that any debris gets into the eyes, which has to be removed with the help of an optometrist. Oftan Dexamethasone drops were prescribed several times to relieve inflammation. Affordable price, efficiency - the advantages of the drug. The drops help very well, there have never been any side effects.

Terms of sell

You can buy Oftan Dexamethasone without a prescription.