Nurofen Long tabs 200mg + 500mg #12

User manual for Nurofen Long

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Composition and action

500 mg of paracetamol and 200 mg of ibuprofen (active substances) in each tablet. Additional components:
    stearic acid;
    magnesium stearate;
    polyvinyl alcohol;
    MCC;
    sodium croscarmellose.
Nurofen Long eliminates pain and inflammation. The interaction of paracetamol and ibuprofen increases the antipyretic and analgesic activity of the drug.

Release form

Capsule pills. In blisters there are 4, 5, 6, 8, 10 or 12 pcs. In a carton pack 1 or 2 plates can be packed.

Pharmacological properties of the drug Nurofen Long

They are explained by the chemical characteristics of the main substances.

Pharmacodynamics

Nurofen Long has a combined effect, which is explained by the active components present in its composition. It has a moderate anti-inflammatory, antipyretic and analgesic effect.
    Ibuprofen and paracetamol have a different mechanism of action, but they enhance each other's activity.
Ibuprofen refers to NSAIDs. Its analgesic effect is associated with the suppression of cyclooskigenase 2 and 1. In addition, the substance is an inhibitor of platelet aggregation.
Paracetamol is a non-narcotic analgesic with analgesic, antipyretic effects.

Pharmacokinetics

Ibuprofen is characterized by high absorption properties. Absorbed by the intestines. Slowly enters the articular cavity, concentrating in the composition of synovial fluid. Cmax is typed in 1-2 hours. T½ does not exceed 2 hours. The element is derived from bile and kidneys.
The duration of Cmax paracetamol kit is from 30 to 40 minutes. T½ - 2.5-3 hours. Method of excretion - the kidneys.

Indications for use

It is recommended to use in the following cases:
    painful periods;
    discomfort in the throat;
    manifestations of colds;
    toothache / headache;
    fever;
    neuralgia;
    ulcerative pathologies accompanied by pain;
    muscle / joint pain;
    pain in the spinal column;
    rheumatic conditions.

Application and dosage of Nurofen Long

Orally, with water. The drug is not recommended for prolonged use.
The average dose is 1 tablet three times a day. The maximum amount of funds - 2 tablets. If after 3-4 days of admission negative symptoms persist, treatment is canceled.

Can I use for pain in the kidneys

Anesthetic drug in this case should be taken with a minimum interval of 4 hours. In this case, the duration of therapy should not exceed 5 days.

How long does Nurofen Long work

The combination of active substances has an operational therapeutic effect. Nurofen Long begins to act 15-20 minutes after taking 1 tablet. The action lasts up to 9 hours. Course duration should be determined by a specialist.

Contraindications

It is forbidden to drink pills for such conditions and diseases:
    confirmed hyperkalemia;
    hemorrhagic diathesis;
    combination with other drugs, where there is paracetamol;
    age less than 12 years;
    allergic to ibuprofen, paracetamol or minor substances of the composition of the MP;
    pregnancy in the 3rd trimester;
    bleeding;
    decompensated stage of heart failure.
Relative restrictions (drug is used carefully):
    the whole period of the implementation of aortic coronary bypass surgery;
    nephrotic conditions;
    exacerbation of allergies;
    bronchial asthma;
    hypertension;
    heart failure;
    1 and 2 trimesters of pregnancy;
    old age;
    exacerbation of urolithiasis;
    lactation;
    liver failure and cirrhosis;
    diabetes.

Side effects

In some organs and systems, the occurrence of negative reactions may be noted:
    biliary tract and liver: jaundice, changes in the level of urea and creatinine, increased activity of liver enzymes;
    the digestive system: pain in the abdomen, the urge to vomit, disruption of the organs of the gastrointestinal tract;
    urinary system: exacerbation of kidney failure, swelling, cystitis, papillary necrosis;
    respiratory system: discomfort in the sternum, bronchial spasms, shortness of breath;
    SSS: heart failure, thrombotic states;
    lymphatic system / blood: anemia, aplastic anemia, agranulocytosis;
    immunity: hypersensitivity reactions in the form of a rash, itching.

Overdose

It is manifested by nausea, vomiting and general deterioration of well-being. Severe conditions are accompanied by headache, ringing in the ears and problems with the gastrointestinal tract.
Therapy involves the elimination of symptoms, control of heart rate and major clinical indicators. In this case, the patient must drink enterosorbents and clean the intestines by means of an artificial invocation of vomiting.

special instructions

It is advisable to drink the medicine for an extremely short time and in minimal doses in order to eliminate negative symptoms.

Can I take during pregnancy and lactation

In 1 and 2 trimester childbirth pills should be used carefully. When planning a pregnancy, it is better not to accept them.
During lactation, Nurofen Long is taken with extreme caution, while you should refrain from breastfeeding.

Use in childhood

Nurofen is not prescribed for children under 12 years of age.

In case of impaired renal function

If QC does not reach the mark of 30 ml per minute, then the use of medication should be discarded.

With abnormal liver function

Exacerbation of liver disease - a contraindication to taking pills.

Drug interactions

When taken together with other pharmaceutical agents, nonspecific reactions may occur:
    antiemetic drugs: decrease in the speed of absorption of paracetamol;
    anticoagulants: increase their activity;
    GCS: the risk of developing gastric ulcers and bleeding in the intestines increases, ulcers are aggravated;
    lithium-containing drugs: increases the level of lithium in the blood;
    Tactrolum: increases the likelihood of nephrotoxicity;
    Zidovudine: hematotoxicity increases;
    caffeine: increases the analgesic effect.

Which is better - Nurofen Long or Express

Drug Express includes only 200 mg of ibuprofen, and paracetamol in the amount of 500 mg is additionally present in Long. The last drug has a more pronounced and prolonged action.

Terms and conditions of storage

Dry / dark place. The optimal storage temperature is + 10 ° ... + 25 ° C. To protect access for children. Stored for 3 years.

Reviews

Valeria, 40 years old
Recently decided to try a new drug Nurofen Long. Previously used its counterparts. Headache helps very quickly. After taking one pill, discomfort disappears within 10-15 minutes. It is inexpensive medicine, adverse reactions when taking it, and if there are, then in rare cases and with inadequate reception. Now, with my husband, we are planning to purchase a bulk lot and take it to all our relatives so that they can quickly and efficiently get rid of the pain of various etiologies.
Igor, 35 years old
I have been working as an accountant for many years. Nervous activity, often having to deal with a headache. Recently, a colleague advised to purchase these pills to solve such problems. Without a second thought, I went to the pharmacy after work, especially since Nurofen Long was cheap. Now, at the first sign of pain, I immediately drink 1 pill.
Galina, 24 years old
Daddy has arthritis. He has pains so strong that no other medicine can cope, except for these pills. Drinks them before bedtime to ensure a proper rest until the morning. The next day, if there is an indisposition, drink another pill.

Terms of sell

You don't need a prescription from a doctor tu buy Nurofen Long.