Nimica tabs 100mg #20

Nimica user manual

You can buy Nimica here

Composition and release form

The main component of the drug, causing its effects, is nimesulide. The amount contained in the drug varies from 50 to 100 mg.
Additionally, starch, cellulose, silica, citric acid, sodium starch, talc, magnesium stearate are included in the composition. Contains the preparation of flavoring to flavor banana or other fruits.
The drug is available in tablet form of a flat round shape. On the surface there is a chamfer, on one side - the risk. Tablets are yellow or slightly yellowish.
In one carton box - two blisters of 10 tablets each. The drug is manufactured in India by Ipca Laboratories.

pharmachologic effect

Nimica refers to nonsteroidal anti-inflammatory drugs. Being a medicine of a new generation, it inhibits the synthesis of cyclooxygenase II. This enzyme is involved in the production of mediators that cause swelling, pain, inflammation. It affects both areas where there are injuries and in the spinal cord, where it blocks the passage of pain impulses.
Reduces platelet activity. It does not affect the process of phagocytosis and hemostasis. This causes the following effects on the body:
    anti-inflammatory;
    pain medication;
    antipyretic
It is noted that nimesulide reduces the production of histamine, as a result, reduces the likelihood of development and intensity of bronchospasm.
The active component is able to inhibit the synthesis of proteins involved in the destruction of tissue, cartilage collagen (for example, urokinase, metalloprotease).
Nimesulide has an antioxidant effect. Once in the body, it reduces the formation of the active form of oxygen, slows down the effect of free radicals. This happens due to a decrease in the production of myeloperoxidase.
The drug is taken orally, after entering the gastrointestinal tract is rapidly absorbed. The optimal effect occurs on average after two hours, sometimes after three hours. Absorption is slowed down if Nimica is taken simultaneously with food, however, the percentage of absorption remains unchanged - about 99%. The main action of the nimesulide metabolite is hydroxynimesulide, which is formed in the liver.
    The metabolic products of the active substance are excreted mainly in the urine (up to 70%). The balance goes with feces. Up to 98% of the drug is excreted during the day.
In the body, the active substance is not accumulated. However, if the liver fails, the metabolism of the drug fails, its concentration in the blood increases significantly. In this case, the accumulative effect can be observed. The use of the drug in severe liver pathologies can therefore be fatal.

Indications

Nimica appointed to relieve acute pain, signs of inflammation, lowering the temperature in the following pathologies:
    osteoarthritis;
    rheumatism developing outside the joints;
    effects of surgical interventions, manifested in intense pain, the occurrence of inflammation;
    respiratory diseases;
    painful menstruation;
    posttraumatic morbidity;
    arthritis;
    pain in the teeth, including after treatment;
    myalgia.
See also: Ibuprofen rules of administration: indications and accurate dosage.
Recently, manufacturers consider it inexpedient to use Nimica and other drugs containing nimesulide to combat high temperatures and ARVI. The drug is used for second line therapy. Admission is valid in the presence of evidence and prescription.

Instruction

The dosage is prescribed based on the patient's condition. It is important to bear in mind that taking the drug should last as little as possible. This will reduce the risk of side effects. It is recommended to accept Nimica after food. The period during which the medicine is used cannot exceed 15 days.
The dosage depends on the age of the patient:
    Patients over 18 years old are shown taking Nimica in a daily dosage of 200 mg divided in two times.
    After 12 years, children are prescribed the drug, based on their body weight. The average dosage is 1.5 mg per kg of body weight. The recommended frequency of admission - no more than three times a day. The maximum daily dosage is 5 mg per 1 kg of weight. Before taking the pill dissolve in pure water, tea.
    The drug is contraindicated in children under 12 years, however, in some cases, the reception is prescribed under the strict supervision of a physician.

Pregnancy and lactation

The drug is not prescribed to pregnant women and nursing mothers. The main reason for this is the lack of evidence of toxic effects on the child.
In this regard, in special cases Nimica is appointed, but only after the doctor assesses the risk to the mother and possible consequences.

Elderly patients

Particular attention is paid to patients in old age with pathologies of the heart, liver, kidneys. In this case, medical supervision is required.
Dosage adjustment recommended for adult patients is not performed.

Side effects

Nimica refers to the drugs of the new generation, it distinguishes it from the drugs of the first generation with fewer side effects. However, it can also have a strong side effect on the human body. It manifests itself diversely:
    Disorders of the gastrointestinal tract. Manifested in the detection of blood in the fecal masses, staining them black, pain in the stomach, nausea, heartburn. Symptoms of an ulcer, bleeding can appear suddenly, even if the patient has never complained about the corresponding pathology.
    The defeat of the central nervous system is associated with the occurrence of pain in the head, drowsiness, dizziness. Possible lack of coordination of movements. Patients worry nightmares, fears. There is an increase in sweating, reduced visual acuity.
    Immunological reactions. On the skin appears rash in the form of urticaria, redness, erythema. Bronchospasm may occur.
    Changing blood formulas. Perhaps a decrease in the number of platelets, leukocytes, an increase in the number of eosinophils. In some cases, anemia develops.
    Disorder of the kidneys. There are swelling, urine retention in the body.
When taking the drug is not recommended to control mechanisms. It is contraindicated to perform dangerous work at height, in the mine, in other similar conditions. This is due to a possible impairment of consciousness, slowness, the occurrence of headaches.
Detection of side effects is the basis for stopping Nimica treatment.

Overdose

The main signs of overdose are lethargy, fatigue, nausea, pain in the stomach. In severe cases, there may be coma, breathing problems, swelling of internal tissues, bleeding in the stomach or intestines.
If these symptoms are found, symptomatic as well as maintenance therapy is indicated. Gastric lavage is performed, sorbents and laxative preparations are prescribed to the patient.
Be sure to monitor the work of the kidneys, liver. According to medical research, hemodialysis in overdose with nimesulide is not effective.

Contraindications

The drug is quite powerful anesthetic. Before you start taking, make sure that there are no contraindications. These include:
    age up to twelve years;
    aspirin asthma;
    intolerance to the components of tablets, aspirin, other drugs belonging to the NSAID group;
    gastric diseases: ulcers, acute gastritis, bleeding, Crohn's syndrome;
    clearly expressed disorders of the liver;
    diagnosed hemorrhagic diathesis;
    hemostatic disorders;
    renal dysfunction characterized by creatinine clearance less than 30 ml per minute;
    drug and alcohol addiction.
Nimica is contraindicated when taking alcoholic beverages, other drugs from NSAIDs, drugs containing ethanol.
    Caution should be observed in patients with a history of hypertension, diabetes.

Interaction with other drugs

Nimica can not be used with certain drugs because of the negative effect that they have on each other:
    When blood clotting is disturbed and anticoagulants are taken, the likelihood of bleeding increases. Therefore, the drug is not used in severe pathologies. If necessary, sharing requires regular blood clotting.
    The active ingredient of the drug reduces diuresis, reduces the effectiveness of diuretics for the withdrawal of sodium and potassium. With the simultaneous appointment of diuretics and Nimica need control of the heart, blood pressure.
    All nonsteroidal anti-inflammatory drugs cause an increase in the content of lithium in the blood, increasing its toxic properties. In this regard, the combined use of lithium and nimesulide requires control of this substance in the plasma.
    It is recommended to stop taking methotrexate one day before using Nimica or one day after its cancellation.
    Using together with Cyclosporin leads to depression of the kidneys.
    Use with antifungal, antiepileptic drugs, as well as anti-tuberculosis drugs, can cause a hepatotoxic effect.
Interaction with other components and medicinal substances showed no critical changes.

Storage

The drug is stored no more than 24 months from the date of issue. After this period Nimica use is prohibited.
Storage conditions:
    Ambient temperature is not higher than 25 ° С, optimal is from + 15 ° С.
    The storage location must be well protected from sunlight.
    It is important that children do not have access to the medicine.

Reviews

    Tatyana

Recently, due to overgrown fibroids, I have been suffering from severe pain during menstruation. Nimica allows you to quickly get rid of them, lead a normal life, do your favorite work. No side effects were observed;
    Oleg, 27 years old

I had an accident, in the end - a fracture of both legs with an offset. We performed the operation, after it there were terrible pains. The doctor prescribed Nimica. Only she saved me. I remember that I had a little headache after taking it. But I am not sure that it was from her, because then I took a lot of other pills;
    Anastasia, 39 years old

For many years I suffer from congenital arthritis. It happens so much that the joints hurt so much that even with a wolf howl, especially in winter, after standing at the bus stop for several minutes. For such cases, the doctor prescribed Nimica. I drink when much unbearable. Warned me that I can not drink it often because of possible side effects. I try to endure, I make compresses, if more than 7-10 days, the medicine has been cut.

Terms of sell

You don't need a prescription to buy Nimica.