Methionine tabs 250mg #50

Instruction for Methionine

Methionine is a hepatoprotective agent with a metabolic effect and detoxifying effect.

Release form and composition

Dosage form - film-coated tablets: they have a round biconvex shape, pink color with insignificant impregnations, on the cross section two different layers (10 pcs each in blisters, in a cardboard bundle 1, 2 or 5 packs).
The active substance is methionine, in 1 tablet - 250 mg.
Auxiliary components: potato starch, methyl cellulose, stearic acid, wheat flour, sucrose, magnesium carbonate, talc, refined sunflower oil, beeswax, dye azorubin.

Pharmacodynamics

Methionine is an indispensable amino acid - a donor of mobile metal groups; it has a hepatoprotective and metabolic effect on the body. It is necessary for the synthesis of choline, a deficiency of which causes a violation of the synthesis of phospholipids and the deposition of neutral fat in the liver. It takes part in the exchange of sulfur-containing amino acids, the synthesis of creatinine, epinephrine, and other biologically important compounds. It also activates the action of vitamins (folic and ascorbic acids, B12), proteins, enzymes, hormones, participates in deamination, remethylation, decarboxylation, etc.
Essential for the detoxification of xenobiotics.
With atherosclerosis, methionine lowers cholesterol and increases the concentration of phospholipids in the blood.

Pharmacokinetics

Methionine is easily absorbed from the intestine, in a small amount excreted in the urine.

Indications for use

    Treatment of liver diseases (including hepatoses, hepatitis, cirrhosis) occurring with fatty infiltration of hepatocytes;
    Prevention of toxic liver pathologies (due to exposure to alcohol, chloroform, arsenic, benzene);
    Combined therapy of protein deficiency of various origins.

Contraindications

    Hepatic encephalopathy;
    Viral hepatitis;
    Severe liver failure;
    Age to 6 years;
    Hypersensitivity to the components of the drug.
According to the instructions, it is recommended that methionine be prescribed with caution to patients with renal failure (due to the risk of hyperazotemia).

Instructions for use: method and dosage

The tablets are taken orally 30-60 minutes before a meal.
Recommended single dose of the drug:
    Adults: 2-6 tablets;
    Children over 6 years: 1-2 tablets.
The frequency of taking the drug 3-4 times a day, the duration of therapy is from 10 to 30 days.
An alternative use of the drug is the alternation of 10 days of taking tablets with ten-day intervals.

Side effects

When taking Methionine, the appearance of nausea, vomiting (against the background of an unpleasant taste and smell), the development of allergic reactions; in case of an overdose - tachycardia, lowering blood pressure, disorientation (symptomatic therapy is indicated).

Overdose

Symptoms: tachycardia, disorientation, decreased blood pressure.
Symptomatic treatment recommended.

Special instructions

The dosage regimen of methionine tablets must be coordinated with the dose of simultaneously used amino acids, since unbalanced use of the drug can cause damage to the cells of the digestive system, including the liver.
The effect of the drug does not affect the patient's ability to drive vehicles and mechanisms.

Pregnancy and lactation

The use of methionine during pregnancy requires strict adherence to dosage.
During breastfeeding, you should refrain from using the drug, since there are no updated data on its safety.

Use in childhood

It is forbidden to use the drug to treat patients under the age of 6 years.

With impaired renal function

Because of the danger of an increase in hyperazotemia in renal failure, the drug should be used with caution.

With impaired liver function

It is forbidden to use methionine in severe liver failure.

Drug interaction

The interaction of methionine with other drugs has not been established.

Terms and conditions of storage

Store in a dry, dark place at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 5 years.

Reviews

Most often, there are reviews about Methionine from pregnant women and bodybuilding athletes. Both categories of users note the availability of the drug and draw attention to the fact that when taking it, the dosage and treatment regimen must be strictly observed.
According to doctors, methionine can significantly improve the condition of patients with atherosclerosis or impaired liver function. Doctors do not recommend taking this drug for weight loss (with the exception of a patient following a vegetarian diet or eating too little protein).

Terms of sell

You don't need a prescription to buy Methionine.