Guttalax tabs 5mg #50

Guttalax instruction

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Guttalax is a drug with a laxative effect and stimulates intestinal motility.
The drug is available in the form of tablets. The tablets have a round, cylindrical shape, are painted white and odorless. Packed in polypropylene tubes of 20 or 50 pieces.

Composition and pharmacological action of Guttalax

The main active ingredient of the laxative is sodium picosulfate monohydrate. Additionally, both dosage forms contain auxiliary compounds.
The composition of the tablets contains:
    magnesium stearate;
    lactose monohydrate;
    silicon dioxide colloidal;
    corn starch;
    Hydrolyzed potato starch.
Sodium picosulfate is a laxative from the triarylmethane group.
As a local laxative, the active active compound of the drug undergoes cleavage under the action of bacteria in the large intestine, providing a stimulating effect on the mucous membrane of the large intestine, and cleavage products activate its peristalsis. Under the influence of sodium picosulfate, the accumulation of electrolytes and water in the large intestine of the gastrointestinal tract is provided, which helps to stimulate the bowel movement, soften the stool and reduce the time of its evacuation.
The active component of Guttalax effectively acts on the body at the level of the colon, which enhances the natural process of discharge of feces from the lower parts of the gastrointestinal tract. The drug does not affect the absorption and digestion of food consumed in the small intestine.
The absorption of sodium picosulfate in the lumen of the gastrointestinal tract is at an insignificant level. The active component is completely metabolized by cells of the tissues of the liver and intestinal wall, while the formation of pharmacologically inactive glucuronide occurs.
After ingestion, the drug enters the large intestine, in the distal colon of sodium, picosulfate breaks down with the formation of the active metabolite - bis- (p-hydroxyphenyl) -pyridyl-2-methane. The period of development of the laxative effect depends on the release rate of the active metabolite and most often varies in the range from 6 to 12 hours after taking the laxative.
The active compound enters the systemic circulation in a small amount. Excretion of the drug received into the bloodstream is carried out using the kidneys in the urine in the form of glucuronide for 48 hours.

Pros

    Convenient form of drug release
    The implementation of the medication is carried out without presenting a prescription leaflet
    Availability of the use of the drug during pregnancy, starting from 12 weeks
    Economical drug packaging
    The drug is approved for use in childhood

Cons

    May cause addiction during prolonged use
    When combined with certain drugs, it causes a violation of the water-salt balance in the body
    Possibility of side effects
    The presence of a large list of contraindications

Instructions for use of the drug

Guttalax in drops and tablets should be taken in accordance with the recommendations of the instructions for use. In accordance with the annotation to the drug, it is used as a laxative.

Indications for use

The use of the medication is recommended in cases requiring relief of the bowel movement.
Such cases are:
    Constipation on the background of atony and hypotension of the colon.
    Constipation due to medication.
    Constipation caused by dietary disorders and intestinal dysbiosis.
    Regulation of bowel movements during proctitis, anal fissures and hemorrhoids.
    Irritable bowel syndrome with a predominance of constipation and gallbladder disease.
Instructions for the use of Guttalax drops in adults recommends the appointment of a medication before performing surgical interventions on the abdominal organs, as well as before performing diagnostic procedures and examining the large and small intestines.

Method of use

Guttalax in any dosage form is intended for oral use.

Recommended Dosages

Tablets should be taken with plenty of fluids when taken. Children over 10 years old and adults are recommended to use 1-2 tablets, children from 4 to 10 years old - 1 / 2-1 pcs.
    To obtain a guaranteed laxative effect in the morning, it is recommended to take tablets and drops of Guttalax in the evening, before bedtime.

Contraindications

When using Guttalax in accordance with the recommendations of the instructions for use, the possible presence of contraindications in the patient for the use of the medication should be taken into account.
Common contraindications are:
    the presence of pain in the epigastric region of unknown origin;
    development of peritonitis;
    cystitis;
    the development of acute inflammatory processes in the organs of the abdominal cavity;
    metrorrhagia;
    the presence of intestinal obstruction;
    the presence of severe dehydration;
    spastic constipation;
    strangulated hernia;
    the occurrence of bleeding in the gastrointestinal tract;
    the presence of individual intolerance to the active or additional components of the drug.
It is also prohibited to use the tablet form of the drug in pediatric patients who have not reached 4 years of age.
Guttalax tablets, in accordance with the instructions for use, are not allowed to be used if the patient has rare hereditary disorders associated with galactose intolerance - lactase deficiency, galactosemia, glucose-galactose malabsorption.
In the second and third trimester, taking a tablet form of a laxative is allowed only as prescribed by the attending physician. Pediatric patients from 4 to 10 years old are allowed to take tablets only with the permission of a doctor.

Side effects

The use of a medicinal product of any dosage form can provoke the appearance of adverse and undesirable reactions in a patient.
The most common are:
    Cramping and abdominal pain, diarrhea, nausea, vomiting, discomfort.
    Hypersensitivity reactions, including skin reactions, angioedema.
    Dizziness, fainting, the cause of which may be a vasovagal reaction, manifested by cramping in the abdomen or tension during bowel movements.
In the event of an overdose in a patient, the development of symptoms such as hypokalemia, diarrhea, disturbances in water-electrolyte balance, decreased blood pressure, dehydration, and convulsions is observed.
Additionally, ischemia of the muscles of the large intestine may develop due to the use of the drug in doses significantly higher than those recommended for the standard treatment of constipation.
In chronic overdoses, the patient may experience the development of urolithiasis, pain in the abdomen, chronic diarrhea, secondary hyperaldosteronism, hypokalemia.
    To stop the effects, gastric lavage and vomiting are used. In some cases, drugs are prescribed to compensate for fluid loss and adjust the water-salt balance.

Drug Interactions and Special Instructions

The combined use of Guttalax with corticosteroids and diuretics increases the likelihood of electrolyte balance. Long-term use of the drug can provoke a deterioration in the tolerance of cardiac glycosides, this is due to a violation of water-electrolyte metabolism.
Self-administration of the drug and prolonged uncontrolled therapy are unacceptable. The medication does not have certain taste qualities.
Broad-spectrum antibacterial drugs provoke a decrease in the laxative effect of Guttalax.

Guttalax Reviews

About Guttalax reviews are mostly positive. Among the advantages, the vast majority of patients note the economical packaging and high effectiveness of the drug in the fight against spastic constipation.
Also, patients and doctors pay attention in their responses to the absence of negative effects on the intestinal microflora and adverse reactions such as pain in the epigastric region with the correct use of the drug in compliance with all requirements of the instructions for use.
Patients indicate, as one of the advantages, the acceptable cost of the drug, as well as the possibility of using funds to eliminate constipation in children.
Patients consider the advantage of the drug to be the possibility of using the drug during pregnancy starting from 12 weeks in the event of constipation associated with gestation.

Terms of sell

You don't need a prescription to buy Guttalax.