Instruction for ACC 600 powder
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ACC 600 powder composition
1 sachet contains:
sucrose - 2045.0 mg;
ascorbic acid 75.0 mg;
sodium saccharinate - 20.0 mg;
lemon flavor - 130.0 mg;
honey flavoring -130.0 mg.
Photo of the packaging of granules ACC 600 mg showing the composition of the drug
homogeneous granules of white color without agglomerates and mechanical impurities with the smell of lemon and honey. When sifting through a 1.5 mm sieve, no particles should remain on the sieve.
Acetylcysteine is a derivative of the amino acid cysteine. It has a mucolytic effect, facilitates sputum discharge due to a direct effect on the rheological properties of sputum. The action is due to the ability to break the disulfide bonds of mucopolysaccharide chains and cause depolymerization of sputum mucoproteins, which leads to a decrease in sputum viscosity. The drug remains active in the presence of purulent sputum.
It has an antioxidant effect based on the ability of its reactive sulfhydryl groups (SH groups) to bind to oxidative radicals and, thus, neutralize them. In addition, acetylcysteine promotes the synthesis of glutathione, an important component of the antioxidant system and chemical detoxification of the body. The antioxidant effect of acetylcysteine increases the protection of cells from the damaging effects of free radical oxidation, a characteristic of an intense inflammatory reaction.
With the prophylactic use of acetylcysteine, a decrease in the frequency and severity of exacerbations of bacterial etiology in patients with chronic bronchitis and cystic fibrosis is noted.
Absorption is high. It is rapidly metabolized in the liver with the formation of a pharmacologically active metabolite - cysteine, as well as diacetylcysteine, cystine and mixed disulfides. The bioavailability of the oral route of administration is 10% (due to the presence of a pronounced effect of "first passage" through the liver). The time to reach maximum concentration (Cmax) in blood plasma is 1-3 hours. Communication with plasma proteins is 50%. It is excreted by the kidneys in the form of inactive metabolites (inorganic sulfates, diacetylcysteine). The half-life (T1 / 2) is about 1 hour; impaired liver function leads to an extension of T1 / 2 up to 8 hours. Penetrates through the placental barrier. Data on the ability of acetylcysteine to cross the blood-brain barrier and excreted in breast milk are not available.
ACC 600 powder indications for use
Diseases of the respiratory system, accompanied by the formation of viscous difficult to separate sputum:
acute and chronic bronchitis, obstructive bronchitis;
bronchiectatic disease, bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiolitis;
Acute and chronic sinusitis, inflammation of the middle ear (otitis media).
ACC 600 mg powder contraindications
hypersensitivity to acetylcysteine or other components of the drug;
peptic ulcer of the stomach and duodenum in the acute stage;
hemoptysis, pulmonary hemorrhage;
sucrose / isomaltase deficiency, fructose intolerance, glucose-galactose deficiency;
the period of breastfeeding;
children's age up to 14 years (for this dosage form).
With caution: a history of gastric and duodenal ulcer, arterial hypertension, bronchial asthma, obstructive bronchitis, liver and / or renal failure, histamine intolerance (long-term use of the drug should be avoided, as acetylcysteine affects histamine metabolism and can lead to the occurrence of signs of intolerance, such as headache, vasomotor rhinitis, itching), varicose veins of the esophagus, adrenal disease.
Use during pregnancy and breastfeeding
Data on the use of acetylcysteine during pregnancy and breastfeeding are limited, so the use of the drug during pregnancy is contraindicated.
If it is necessary to use the drug during breastfeeding, the issue of its termination should be resolved.
ACC granules: 600 mg dosage and method of application
Inside, after a meal.
The granules are dissolved by stirring in 1 cup of hot water. The resulting solution is drunk hot. If necessary, the prepared solution can be left for 3 hours. An additional intake of fluid enhances the mucolytic effect of the drug.
With short-term colds, the duration of the course is 5-7 days. With long-term illnesses, the course of therapy is determined by the attending physician. In chronic bronchitis and cystic fibrosis, the drug should be taken for a longer time to achieve a preventive effect in infections.
In the absence of other prescriptions, it is recommended to adhere to the following dosages:
Adults and adolescents over 14 years of age: 1 sachet (600 mg) 1 time per day.
The strongest medicine. First, son was treated with tracheitis using a mild antibiotic and mantle. Instead of the expected recovery, they ended up in a hospital with a diagnosis of bronchitis ... Here they also prescribed powder ACC 600 in combination with another antibiotic. The magic cure. For some couple of days, the son’s cough became much milder and he began to cough up immediately. Happy with the drug.
I cured pneumonia with the help of powder ACC 600. I liked the medicine in use. Taking a drink is much nicer than sweet sugary syrups or pills, which are difficult to swallow during an illness. No colorants, but flavors are present. I had unpleasant side effects from the gastrointestinal tract, but I can’t say what exactly from the ACC 600 powder, since it was treated not only with this drug.
According to my feelings - the solution acts almost instantly. I took pills mucoltin, after lazolvan. The cough did not go away. After the first packet of the ACC, I directly felt how the sputum began to “move” in the bronchi, which deeply settled inside me and completely exhausted me. The pain during the cough went quickly, in combination with paraffin therapy I quickly got to my feet
Terms of sell
You don't need a prescription to buy ACC 600 powder.