Norbactin tabs 400mg #20

User manual for Norbactin

Reed more and buy Norbactin here

The main component, norfloxacin, is an anniligulator for various aerobic bacteria. The effectiveness of the drug is achieved by destroying the DNA bonds of bacteria. Norbactin actively fights against bacteria resistant to the main groups of antibiotics.
Highly active against most gram-negative bacteria: Escherichia coli (E. coli), Salmonella spp. (salmonella), Shigella spp. (Shigella), Proteus spp. (Proteus), Morganella morganii, Klebsiella spp. (including Klebsiella pneumoniae), Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp., Providencia spp., Haemophilus influenzae, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Neisseria meningitidis.

Release form and composition

Available in the form of tablets coated with a film: white or almost white, oval, with beveled edges, on one side - risk, on the other - extruded quadrangle, in which the inscription "NBT 400" is engraved (10 pieces in blisters or strips , on 1, 2 or 3 blisters or a strip in a cardboard pack).
Ingredients 1 tablet:
    Active ingredient: norfloxacin - 400 mg;
    Additional components: sodium lauryl sulfate, colloidal silicon dioxide, corn starch, magnesium stearate, croscarmellose sodium, microcrystalline cellulose, purified talc;
    Shell composition: macrogol 40, titanium dioxide, hypromellose, purified talc, purified water.

Pharmacological effect

Norbactin has a bactericidal effect. The active component Norfloxacin is an antibacterial agent belonging to the group of fluoroquinolones and has an effect on the bacterial enzyme DNA gyrase, which is responsible for supercoiling, which ensures the stability of the DNA of bacteria. Due to the destabilization of the DNA chain, the death of pathogenic microorganisms takes place.
The following bacteria are sensitive to Norbactin:
    Yersinis enterocolitica;
    Citrobacter spp .;
    Vibrio parahaemolyticus;
    Staphylococcus epidermidis;
    Chlamydia spp .;
    Staphylococcus aureus;
    Legionella spp .;
    Klebsiella spp .;
    Vibrio cholerae;
    Enterobacter spp .;
    Haemophilus influenzae;
    Aeromonas plesiomonas;
    Escherichia coli;
    Shigella spp .;
    Mycoplasma pneumonia;
    Neisseria meningitis;
    Campylobacter jejuni;
    Salmonella spp .;
    Neisseria gonorrhoeae;
    Hafnia, Proteus spp.
Anaerobic bacteria, Ureaplasma urealyticum, and Nocardia asteroids are insensitive to Norbactin.
The duration of the therapeutic effect is not less than 12 hours.

Indications for Norbactin

The medicine in the form of tablets must be taken in full from 7 to 10 days in such clinical pictures, while it is important to take into account Norbactin interaction, the potential risk of side effects:
    gastrointestinal tract infections, intestinal disorders;
    prevention of sepsis with neuropathy;
    “Travelers' diarrhea” (other problems when the stomach works during the acclimatization period);
    uncomplicated gonococcal infection, initial stage;
    infection of the genital organs, urinary system, for example, gonorrhea.
The characteristic drug is prescribed for such diagnoses of the body:
    endometritis;
    salmonellosis;
    prostatitis;
    cervicitis;
    shigellosis.

Contraindications for Norbactin

Since fluoroquinolones are able to accumulate in the connective tissue and cartilage, destroying them, norfloxacin preparations should not be taken by pregnant and lactating women, children and adolescents until adulthood.
In addition, Norbactin is contraindicated in persons with hypersensitivity, some deficient conditions, epilepsy, atherosclerosis and impaired blood circulation in the brain vessels, liver and kidney failure.

Dosage and method of use

The instructions for use indicate that Norbactin - a drug for oral administration: tablets should be swallowed whole and drink plenty of liquid. To achieve the maximum therapeutic effect is possible by taking Norbactin on an empty stomach - 1 hour before or 2 hours after a meal.
The dose and duration of treatment in each case is determined by the doctor depending on the evidence and the severity of the disease.
Average recommended doses:
    Acute uncomplicated gonococcal infection: 800 mg once;
    Acute uncomplicated cystitis: 200-400 mg 2 times a day for 3-5 days;
    Other acute urinary tract infections: 400 mg 2 times a day for 7-10 days;
    Genital infections: 400-600 mg 2 times a day for 7 days;
    Infectious diseases of the gastrointestinal tract: 400 mg 2-3 times a day, a course of 3-5 days;
    Preventing travelers' diarrhea in epidemically unfavorable areas: 400 mg 1 time per day, the duration of therapy is necessary, but not more than 21 days;
    Recurrent and chronic recurrent infectious diseases of the urinary system: 400 mg 2 times a day for 4 weeks. In case of relapse, 400 mg 1 time per day for up to 12 weeks;
    Prevention of sepsis in patients with neutropenia: 400 mg 3 times a day for 8 weeks.
Patients with impaired renal function (creatinine clearance less than 20 ml / minute or serum creatinine levels greater than 5 mg / 100 ml) and patients undergoing blood purification (hemodialysis) should be given 1 full dose 1 time per day or ½ therapeutic dose 2 times a day.

Side effects

Like any other drug, Norbactin tablets have a number of side effects:
    In women, the development of vaginal candidiasis;
    On the part of the skin - urticaria, the appearance of rashes, itching, redness of the skin;
    On the part of the urinary system - dysuric phenomena, the development of interstitial nephritis;
    On the part of the nervous system - dizziness, confusion, headaches, loss of sensitivity in the fingertips, anxiety, drowsiness and lethargy, fatigue;
    On the part of the cardiovascular system - increased heart rate, changes in blood pressure, the development of cardiac arrhythmias, vasculitis;
    On the part of the digestive system - nausea, heaviness and pain in the stomach, flatulence, increased gas formation, diarrhea, enlarged liver, tongue lining and appetite, increased liver transaminases, in severe cases, impaired liver function;
    On the part of the blood system - reducing the number of platelets and leukocytes in the blood.
With the development of such side effects, drug therapy should be interrupted and seek medical help.

Overdose

In case of Norbactin overdose, vomiting, dizziness, drowsiness, general weakness, nausea, increased sweating, puffiness of the face may occur. For such symptoms, gastric lavage and adequate hydration therapy with forced diuresis are required. The patient is recommended to be placed for several days in a hospital and to be examined (hemodialysis or peritoneal dialysis can be prescribed).

special instructions

It should be used with caution in patients with epilepsy, convulsive syndrome of a different etiology, with severe impaired renal and hepatic function. During treatment, patients should receive a sufficient amount of fluid (under the control of diuresis).
Norfloxacin should be taken no less than 2 hours before or 2 hours after taking antacids or preparations containing iron, zinc, magnesium, calcium or sucralfate.

Drug interactions

When using Norbactin, you must consider the interaction with other drugs:
    Reduces the effect of nitrofurans.
    With simultaneous use of cyclosporine norfloxacin, an increase in the concentration of the latter in the blood plasma is observed.
    With simultaneous use of norfloxacin with warfarin increases the anticoagulant effect of the latter.
    With simultaneous use of norfloxacin reduces theophylline clearance by 25%, therefore, with simultaneous use, the dose of theophylline should be reduced.
    While taking norfloxacin and antacid agents or drugs containing iron, zinc, magnesium, calcium or sucralfate, the absorption of norfloxacin is reduced due to the formation of complexones with metal ions (the interval between their intake should be at least 4 hours).
    Simultaneous administration of norfloxacin with drugs that have the potential ability to reduce blood pressure, can cause a sharp decrease. In this regard, in such cases, as well as with the simultaneous introduction of barbiturates, anesthetics, heart rate, blood pressure, ECG indicators should be monitored. Simultaneous use with drugs that reduce the epileptic threshold may lead to the development of epileptiform seizures.

Reviews

We picked up some reviews of people using the drug Norbactin:
Margo
    A couple of weeks ago I treated acute cystitis with such pills. The pain during urination quickly passed, but there were problems with the stool (liquid feces). Constantly ran to the toilet, although taking medicine on an empty stomach. When it was no longer tolerable (on the 5th day of treatment), Norbactin had to be replaced and a safer Normaks was purchased from the pharmacy.
Andrew
    This treatment was prescribed to me by my attending personal physician, a nephrologist, and told me to drink it twice a day after eating for seven days, if I do not drink it on an empty stomach, you can plant a stomach with an antibiotic. I started to observe light headaches after taking it, my heart began to ache, my urine took on a bright appearance and began to foam. At night I could not fall asleep for a long time, the waist began to disturb me. I think so, this kidney started to let know about itself. Heavy drug for my body. The doctor said that this is a normal antibiotic effect. They all practically harm the body and it is simply impossible to start treatment without them.
Marina
    Took medication for pyelonephritis 10 days. The tablets quickly remove pain, act gently - without side effects. Additionally, the doctor prescribed probiotics, vitamins and drugs to restore immunity. It helped me, therefore, in case of infectious diseases of the urinary tract, I can recommend an appointment.

Terms of sell

You don't need a prescription to buy Norbactin online.