Flemoxin solutab tabs 250mg #20

Instruction for Flemoxin solutab

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The duration of antibiotic therapy for mild and moderate infections is about 5-7 days, and in cases of infections provoked by Streptococcus pyogenes - 10 days. The disappearance of the clinical manifestations of the disease is not a signal for the immediate cancellation of the drug: it should be taken for another 2 days. If the use of flemoxin is accompanied by severe diarrhea, then we can assume the presence of pseudomembranous colitis. In such cases, the drug is subject to cancellation.

Composition and release form

Tablets Flemoxin Solutab dispersible:
    125, 250, 500 or 1000 mg package No. 20 (blisters of 5 pcs., 4 blisters per package);
    125 mg pack No. 14 (blisters of 7 pcs., 2 blisters per pack).
    The dispersible (water soluble) tablets include amoxicillin in the form of amoxicillin trihydrate (Amoxicillin trihydrate), microcrystalline and dispersible cellulose, vanillin, crospovidone, flavors (lemon and mandarin), magnesium stearate, saccharin.
Tablets are oval, white or white with a yellowish tinge, with dividing marks on one side, and numerical designation (231, 232, 234 and 236) and the manufacturer's logo on the other.

Pharmacological effect

Amoxicillin is a semi-synthetic β-lactam antibiotic of the penicillin group with a broad spectrum of antimicrobial activity.
The bactericidal properties of the drug are due to the ability to inhibit transpeptidase, disrupt the production of peptidoglycan (the reference protein of the cell walls) during periods of division and growth, to provoke the lysis of microorganisms.
Active against Gram (+) aerobes, including Staphylococcus spp. (Exception - penicillinase-producing strains) and Streptococcus spp. (including Str.pneumoniae and faecalis); Grams of (-) aerobes (gonococci, meningococci, intestinal and hemophilus bacilli, against mirabilis; certain strains of Klebsiella, Shigella and Salmonella, as well as against H. pylori.
Ineffective against strains of P. rettgeri and vulgaris (are indolent), serration, pseudomonads, enterobacteria, morganella morgan. Resistant to the action of amoxicillin mycoplasma, rickettsia and viruses.
A feature of the dosage form is that the tablets are easily dispersed in water to form a dispersion. Due to this, the drug is quickly and fully (more than 93% of the dose taken) absorbed from the alimentary canal. Food intake does not affect the absorption of the substance. TCmax - ranging from 60 to 120 minutes. When taking dispersible tablets, the plasma concentration of amoxicillin is higher than when taking insoluble forms of the drug. The active substance is resistant to acids.

Indications for use

Flemoxin Solutab tablets are intended for the treatment of diseases caused by microorganisms sensitive to Amoxicillin:
    infections of the musculoskeletal system, including osteomyelitis;
    infectious diseases of the skin and soft tissues - pyoderma, streptoderma, boils, carbuncles, erysipelas;
    infectious diseases of the urinary tract and kidneys - urethritis, pyelonephritis, cystitis, interstitial nephritis;
    inflammatory diseases of the female genital organs - adnexitis, salpingitis, cervicitis, endocervicitis, septic complications after abortion or childbirth, endometritis;
    diseases of the respiratory system of the inflammatory and infectious nature - complicated sinusitis, sinusitis, tonsillitis, tonsillitis, pharyngitis, bronchitis, tracheitis, hospital pneumonia.

Contraindications

The use of Flemoxin Solutab is contraindicated in patients with individual intolerance to the components of the drug and other beta-lactam antibiotics, including other carbapenems, cephalosporins and penicillins.
Diseases / conditions in which the drug is administered with caution:
    Infectious mononucleosis;
    lymphocytic leukemia;
    a history of gastrointestinal diseases (especially colitis associated with the use of antibacterial agents);
    renal failure;
    allergic reactions, including multivalent hypersensitivity to xenobiotics (including a history of);
    pregnancy;
    breastfeeding period.

Appointment during pregnancy and lactation

The use of the drug Flemoxin Solutab during pregnancy and lactation is possible if the expected benefit of therapy for the mother exceeds the risk of side effects in the fetus and infant.
In small quantities, amoxicillin is excreted in breast milk, which can lead to the development of sensitization phenomena in an infant.

Dosage and method of use

As indicated in the instructions for use, Flemoxin Solutab should be taken orally before, simultaneously with or after meals.
Flemoxin Solutab can be swallowed whole, chewed or divided into parts and washed down with a glass of water, or diluted in water with a volume of 20 or 100 ml to form a syrup or suspension, having a pleasant fruity taste.
    The regimen of the drug is set by the doctor on an individual basis. In determining it, it takes into account the severity of the condition, the age of the patient and the sensitivity of the pathogen to amoxicillin.
The recommended dosing regimen in the treatment of diseases of moderate / mild severity:
    children 1-3 years old: 2 times a day, 250 mg or 3 times a day, 125 mg;
    children 3–10 years old: 2 times a day, 375 mg, or 3 times a day, 250 mg;
    children from 10 years and adults: 2 times a day, 500-750 mg, or 3 times a day, 375-500 mg.
The dose of Flemoxin Solutab for children (including those under the age of 1 year) depends on weight and is 30–60 mg / kg per day, divided into 2–3 doses.
In cases of severe infections, as well as in the treatment of hard-to-reach foci of infection (for example, otitis media in the acute course), the daily dose of Flemoxin Soluteba is recommended to be divided into 3 doses.
In high doses, the drug is used for recurrent infections, chronic diseases and infections in severe course: children - 60 mg / kg per day, divided into 3 doses, adults - 3 times a day, 750-1000 mg.
In acute uncomplicated gonorrhea, a combination therapy is administered: Flemoxin Solutab - 3000 mg and probenecid - 1000 mg (once).
With functional impairment of the kidneys (in patients with creatinine clearance ≤ 10 ml per minute), a dose reduction of 15–50% is indicated.
Course duration:
    moderate / mild infections: 5–7 days; more prolonged use (at least 10 days) is indicated in cases of treating infections that are caused by Streptococcus pyogenes;
    severe infections, chronic diseases: the duration is determined by the clinical picture; after the symptoms disappear, therapy is continued for another 48 hours.

Adverse reactions

Side effects manifest as:
    nausea, changes in taste, diarrhea, vomiting, a moderate increase in the activity of liver enzymes (sometimes), hemorrhagic and pseudomembranous colitis (extremely rare);
    interstitial nephritis (extremely rare);
    hemolytic anemia, neutropenia, agranulocytosis, thrombocytopenia.
When using the drug in the form of dispersible tablets, no adverse events on the part of the nervous system were noted.
The use of the drug may be accompanied by the development of hypersensitivity reactions, which are expressed in the form of a rash (mainly specific maculopapular), exudative erythema multiforme (rarely), angioedema and anaphylactic shock (in exceptional cases).

Overdose

Flemoxin Solutab is prescribed in a specific dosage, however, in the case of an overdose, gastric lavage is performed, activated charcoal, saline laxatives are given, water-electrolyte balance is restored. Such events are held only in the hospital under the strict supervision of medical personnel.

special instructions for Flemoxin Solutab

With caution used in patients prone to allergic reactions.
Against the background of combination therapy with metronidazole, alcohol is not recommended.
Amoxicillin in combination with metronidazole is not recommended for use in patients younger than 18 years; should not be used for liver disease.

Compatibility with other drugs

When using Flemoxin Solutab, you must consider the interaction with other drugs:
    Amoxicillin may reduce the effectiveness of oral contraceptives.
    Amoxicillin reduces the effect of drugs, in the process of metabolism of which PABK is formed.
    Antacids, glucosamine, laxatives, aminoglycosides slow down and decrease, and ascorbic acid increases the absorption of amoxicillin.
    Amoxicillin enhances the effect of indirect anticoagulants by suppressing the intestinal microflora, reduces the synthesis of vitamin K and the prothrombin index.
    With the combined use of amoxicillin and clavulanic acid, the pharmacokinetics of both components does not change.
    Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs reduce tubular secretion of amoxicillin, which may be accompanied by an increase in its concentration in blood plasma.
    With the simultaneous use of amoxicillin with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin), synergism is manifested; with bacteriostatic antibiotics (including macrolides, chloramphenicol, linkosamides, tetracyclines, sulfonamides) - antagonism.

Reviews

We offer you to read the reviews of people who used Flemoxin Solutab:
Natalia
    This antibiotic is very weak only for pichikhaniya and snot ... When pneumonia, an experienced doctor will not when not appoint it. Only in injections or strong in pill form but not always. One antibiotic to drink constantly is not addictive and as a result, waste of money and the result is zero. Antibiotics should be alternated after 3-5 months (so as not to repeat). Amoxicillin is part of Flemoxin. Before you buy Flemoxin, buy one plate of Amoxicillin. It costs a penny. Put a sour taste under your tongue, which means it does not suit you.
Margarita
    I remember how a friend told me that her friend had spent all her life in hospitals. It all started with how staphylococcus was found in her daughter. The baby was still very small and she was prescribed flemoxin Solutab. They were treated for about a week and how good it is that the drug helped. The baby was healthy. And although there were no side effects, but then they went to hospitals for a long time (and still).
Valeria
    I was prescribed Flemoxin Solutab with a strong sore throat. Very sore throat, hoarse, lost his voice. The doctor appointed a rinse and this antibiotic. I liked the effect of the drug - the symptoms of the disease passed quickly enough. On the second day I started to feel much better. The drug is well tolerated, no side effects are not observed. I was pleased with the action of the medicine. The tool is very quickly absorbed in the mouth. Passed fever, pain, sore throat. I took pills for five days, three days a day.

Terms of sell

You can buy Flemoxin solutab without a prescription.