Lordestin instruction
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Lordestin is an active antihistamine of the new generation. Desloratadine, which is a histamine antagonist of long duration, acts as the main active ingredient of the drug. The drug is produced in two dosage forms: tablets and syrup for oral administration. The composition is well tolerated and effectively eliminates the symptoms of allergies, adverse reactions on the background of the reception can not be traced. The drug is actively used in pediatrics.
Dosage Form
The drug Lordestin produced pharmacological companies in the form of tablets intended for oral use and in the form of syrup.
Description and composition
The drug is made in the form of syrup and tablets intended for oral administration.
As the active substance of drugs, regardless of the dosage forms acts desloratadine.
The list of excipients included in the syrup can be represented as follows:
sorbitol;
propylene glycol;
lemon acid;
sodium citrate;
sodium cycloact;
hypromellose;
disodium edetade hydrate;
almond flavoring;
water.
Syrup has a transparent color and uniform structure. These auxiliary components provide the desired dosage form.
Lordestin is also produced in the form of film-coated tablets. The active substance remains unchanged. Tablets have a round, biconvex shape, white or almost white on a break.
The list of auxiliary components present in the composition can be represented as follows:
microcrystalline cellulose;
calcium phosphate dihydrate;
peeled starch;
colloidal silicon dioxide;
magnesium stearate.
The composition of the film shell contains the following elements:
yellow opadry;
titanium dioxide;
talc;
soy lecithin;
aluminum varnish;
xanthan gum.
Pharmacological group
Lordestin is a blocker of histamine H receptors. Considered as the primary metabolite of loratadine. The agent inhibits the release of histamine and leukotriene from mast cells. The tool prevents the course and prevents the occurrence of allergic diseases. The composition has a pronounced antipruritic, antiexudative and antiallergic effect. The composition reduces capillary permeability and prevents tissue swelling. The remedy does not have a sedative effect, its use in the doses recommended by the instruction does not affect the speed of psychologic reactions. When used in doses higher than recommended, drowsiness may occur.
After oral administration, the active substance is actively absorbed from the gastrointestinal tract. The required concentration in the blood plasma can be traced within 30 minutes after administration. With a single dose dose, the maximum concentration can be traced after 3 hours. The substance does not penetrate through the placental barrier. The half-life of the drug is 27 hours.
Indications for use
The list of indications for use of the product can be represented as follows:
allergic seasonal rhinitis;
sneeze;
rhinorrhea;
nasal congestion;
itchy eyes;
lacrimation;
eye redness;
cough;
pruritus and rash.
for adults
Patients of this age group can use such a tool without significant limitations in doses, according to age. Lordestin is well tolerated and promptly excreted from the body, which makes possible its use by patients with impaired liver and kidneys. The composition may be appointed for the elderly. The drug is prohibited to use in the face of adverse reactions. Before starting treatment, you should be familiar with contraindications.
for kids
Lordestin can be used in pediatric practice as prescribed by a doctor. Young children are recommended to use the drug in the form of a syrup. Solid form is prohibited to take persons under the age of 12 years.
for pregnant women and during lactation
Use during pregnancy is somewhat limited. The use of the composition is possible only on prescription. The active substance of the drug does not penetrate the placental barrier, but studies of its mechanism of action have not been conducted to date. Use during lactation is possible after the failure of breastfeeding.
Contraindications for Lordestin
The drug is not recommended for use during pregnancy and breastfeeding. The composition is contraindicated for use in patients with impaired liver and kidney. Lordestin in the form of tablets is limitedly used in pediatrics.
Uses and doses
The dosage regimen is determined individually, depending on the patient's indications for use. In most cases, medications are well tolerated. Adverse reactions in patients can not be traced.
for adults
Patients in this age group should take the drug at a dose of 1 tablet per day. In the case of reducing the effectiveness of Lordestin dose may be increased, but the decision on the correction of the drug regimen should be taken by the doctor.
for kids
Children over the age of 12 use the drug according to the scheme defined for adult patients. Younger children can use the composition in the form of a syrup. The daily dose for children aged 3 to 7 years is 2, 5 ml. For children over 7 years old - 5 ml.
for pregnant women and during lactation
During pregnancy and breastfeeding, the composition can be used only as prescribed by a specialist. Uncontrolled use may cause hazardous effects.
Side effects
The list of adverse reactions that appear on the background of the use of the composition can be represented as follows:
tachycardia;
abdominal pain;
dizziness;
angioedema;
skin rash;
itching;
hives;
anaphylaxis;
dysmenorrhea;
fatigue;
myalgia.
Interaction with other drugs
When combined with ketoconazole, erythromycin, flucetin, no changes in plasma concentration were detected. Lordestin has no effect on the effects of ethanol on the human body.
special instructions for Lordestin
When used in recommended doses, Lordestin does not affect the patient's ability to drive. It is worth remembering that the use in volumes several times higher than therapeutic can cause drowsiness.
Overdose
Receiving dosages of five times the recommended amount is not dangerous for a healthy person. There are no clinical reactions in this case. In the course of laboratory studies conducted on a group of adults who regularly take 20 mg of the drug for 14 days is not accompanied by a clinical response. Significant violations of the work of the cardiovascular system are also absent during this period. The use of the active substance in a dose of 45 mg per day for 10 days also does not lead to violations and does not provoke a prolongation of the half-life.
When using the composition in doses of 5 and 9 times higher than the recommended violations in the body are not traced. The composition is well tolerated.
In severe overdose, symptoms of intoxication may occur. In this case, you should immediately seek medical help. The patient is performed a gastric lavage. We recommend taking enterosorbents.
Storage conditions
The drug in the form of tablets should be stored at a temperature not exceeding 25 degrees. The drug should be protected from children. The maximum storage time is 3 years from the production date.
Lordestin in the form of a syrup is recommended to be stored at a temperature not exceeding 20 degrees in a place protected from children. The composition must be stored in its original packaging. The maximum storage time is 2 years from the production date indicated on the bottle.
The drug Lordestin belongs to the list of over-the-counter formulations and is sold to the public in free sale.
Terms of sell
You don't need a prescription to buy Lordestin.