Livarol supp 400mg #10

Instruction for Livarol

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Livarol is an antifungal agent for topical use.

Release form and composition

Dosage form - vaginal suppositories: from white to white with a yellow, gray or cream tint, have a torpedo shape with a possible marbling of the surface (5 pcs in a blister pack, a carton pack of 1 or 2 packs).
The active substance is ketoconazole, in 1 suppository - 400 mg.
Auxiliary components: base for suppositories (macrogol 1500, macrogol 400), butylhydroxyanisole.

Pharmacodynamics and pharmacokinetics

The active substance of the drug - ketoconazole - is an antimycotic from the group of imidazoledioxolane. It has a fungistatic and fungicidal action, expressed in the suppression of the biosynthesis of ergosterol. This causes a change in the lipid composition in the membranes of fungi.
The drug is active against dermatophytes (Microsporum spp., Epidermophyton floccosum, Trichophyton spp.), yeast (Pityrosporum spp., Candida spp.), streptococci, staphylococci and some other microorganisms.
With intravaginal use, systemic absorption of ketoconazole is negligible.

Indications for use

According to the instructions, Livarol is indicated for the treatment of recurrent chronic and acute vaginal candidiasis.
The drug is prescribed for the prevention of fungal vaginal infections while reducing the body's resistance, taking antibacterial agents and other drugs that violate the natural microflora of the vagina.

Contraindications

    I trimester of pregnancy;
    Hypersensitivity to the components of the drug.
With caution, it is recommended to prescribe the drug to patients under the age of 12 years, in the II-III trimesters of pregnancy, during breastfeeding.

Instructions for use Livarol: method and dosage

Suppositories are intended for deep vaginal administration.
For the procedure, the patient must take a supine position.
The drug is prescribed by a doctor on the basis of clinical indications.
The recommended dosage involves the introduction of 1 suppository 1 time per day. The course of treatment depends on the severity of the disease and can be from 3 to 5 days, with chronic candidiasis - 10 days.
Side effects
    Allergic reactions: urticaria, skin rash;
    Local reactions: vaginal itching, irritation and hyperemia of the vaginal mucosa.

Special instructions

Sexual contacts during the period of treatment can cause the development of allergic reactions in the sexual partner in the form of hyperemia of the penis.
It is advisable to conduct simultaneous treatment of the sexual partner, to prevent a possible recurrence of the disease.

Use during pregnancy and lactation

The drug is contraindicated in the first trimester of pregnancy.
The use of Livarol during pregnancy in the II and III trimesters, as well as during lactation, is possible after assessing the benefit-risk ratio.

Combination with alcohol

During treatment, you must stop drinking alcohol.

Drug interaction

The low resorption of ketoconazole contributes to the absence of a clinically significant interaction of Livarol with simultaneous use with other drugs.

Terms and conditions of storage

Store in a dark, dry place at temperatures up to 25 °C. Keep away from children.
Shelf life - 2 years.

Reviews about Livarol

According to reviews, Livarol is effective in the treatment of thrush. Patients describe various forms and stages of this disease, arguing that therapy has always been effective. The duration of the average course of treatment until the symptoms disappear completely is 5-10 days. Patients note that it is better to put Livarol suppositories at night, because after their dissolution, copious secretions may appear. To stop them, the use of a hygienic swab is allowed.
During pregnancy, Livarol is permissible to use only as directed by a doctor. During this period, drug therapy in most cases leads to positive results, confirmed by laboratory indications.
Some patients are interested in the possibility of using suppositories during menstruation, but practical experience suggests that it is better to interrupt therapy during this period.
After treatment with the drug, relapses of thrush are possible, therefore, after the end of the course, periodic monitoring of the state of the vaginal microflora is necessary. It is recommended to use the drug in order to avoid the recurrence of symptoms of the disease simultaneously to both sexual partners.
In addition to efficiency, many note the high cost of the drug.

Terms of sell

You can buy Livarol without a prescription from a doctor.