Instruction for Adenoprosin
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Release form, composition and packaging
Rectal suppositories from yellow to brown, cylindrical conical shape; inhomogeneity of color in the form of inclusions of a darker color is allowed.
Active complex Adenoprosin * - 150 mg, in terms of total protein - 29 mg.
* biomass obtained from the larvae of the gypsy moth (Lymantria dispar) insect.
Excipients: solid fat - Suppositor AM - a sufficient amount to obtain a suppository weighing 2000 mg.
5 pieces. - contour cell packaging (2) - cardboard packs.
Pharmachologic effect
The active ingredient in Adenoprosin is a biomass obtained from the larvae of the gypsy moth (Lymantria dispar) insect, which has anti-inflammatory and antioxidant effects.
The action of the drug Adenoprosin is manifested due to pathogenetic and nonspecific mechanisms. Biologically active components of the drug reduce the formation of A2-phospholipase and the release of arachidonic acid with a decrease in the synthesis of prostaglandins and leukotrienes (inhibit 5-lipoxygenase). The drug reduces capillary permeability, reduces edema and improves microcirculation in the tissues of the prostate gland.
The drug Adenoprosin already in the first days after the start of use improves urodynamic parameters (increases the value of the maximum volumetric urine flow rate, decreases urination time, reduces the amount of residual urine) and the general condition of patients with BPH and chronic prostatitis (decreases the index of chronic prostatitis, decreases the content of leukocytes in secretion of the prostate gland, improves the homogeneity of its echostructure). The drug regulates the tone and peristalsis of the lower segments of the urinary tract, reducing the frequency of urination, incl. at night, and reducing dysuric symptoms, a feeling of incomplete emptying of the bladder and tension during urination.
The antioxidant effect of the drug is expressed by inhibition of lipid peroxidation due to the antioxidant water-soluble compounds of the drug.
Pharmacokinetics
The effect of the drug is the combined effect of biologically active components of the biomass obtained from the larvae of insects of the species Lymantria dispar, therefore, pharmacokinetic studies are currently not possible.
Indications
benign prostatic hyperplasia;
chronic prostatitis (as part of combination therapy).
Dosage regimen
Rectally, 1 supp. 1 time / day (preferably at night at the same time).
The duration of treatment is from 1 to 3 months, depending on the intensity of inflammatory processes in the prostate gland and the severity of BPH symptoms, as well as their combination. If necessary, the course of treatment can be repeated.
Side effect
From the digestive system: rarely - diarrhea or frequent stools; itching in the anal area.
Others: possible allergic reactions, general weakness.
Contraindications for use
hypersensitivity to drug components;
acute urinary retention;
age under 18;
malignant neoplasms of the prostate gland.
Application during pregnancy and lactation
The drug is not used in women.
Application in children
Contraindicated under the age of 18.
Special instructions
The drug should be used after a bowel movement or enema. After administration of the drug, it is recommended that the patient stay in the supine position for 30-40 minutes.
Influence on the ability to drive vehicles and control mechanisms
The drug has no effect on the ability to drive vehicles and control mechanisms.
Overdose
To date, no cases of overdose have been reported.
Drug interactions
To date, no cases of clinically significant drug interactions of Adenoprosin with other drugs have been reported.
Use in the elderly
Rectal suppositories Adenoprosin are not contraindicated in the elderly and can be used as part of the complex therapy of chronic prostatitis in patients over 18 years of age.
Reviews about Adenoprosin
Reviews about the drug Adenoprosin are positive. Patients note the high efficiency of the drug in the complex treatment of chronic prostatitis. The result of treatment is a decrease in the symptoms of the disease, a decrease in painful sensations and the frequency of false urge to urinate, as well as good tolerance and no side effects.
Storage conditions and periods
The drug should be stored out of the reach of children, protected from moisture and light, at a temperature not exceeding 25 ° C. Shelf life is 2 years. Do not use after the expiration date.
Terms of sell
You can buy Adenoprosin without a prescription.