Artrosilene injections 80mg/ml 2ml #6

Artrosilene injections user manual

You can buy Artrosilene injections here

Its active ingredient, ketoprofen, is a derivative of propionic acid and is on the list of essential medicines for humans.
The use of the drug allows to reduce the severity of the inflammatory process, eliminates pain and reduces body temperature. Artrosilene injections has contraindications and can lead to systemic side effects. To avoid the negative effects of the drug on the body, it should be used on the advice of a doctor.

Dosage form

Injections Artrosilene produced in Italy by the pharmaceutical company Dompe Pharmacheutichi S.p.A. The drug is available in the form of a clear, colorless or light yellow sterile solution intended for intramuscular or intravenous administration. Therapeutic fluid is poured into 2 ml ampoules of dark glass. The vials are packaged in 6 pieces in plastic pallets. Inside each brand package is 1 pallet with ampoules and instructions for use for the drug solution.

Components and action

Pharmacological action Artrosilene injections provides ketoprofen, presented in it in the form of lysine salt. Its concentration in 1 ml of solution is 80 mg. Additionally, the product includes sodium hydroxide, citric acid and sterile water.
Ketoprofena lysine salt when administered intramuscularly or intravenously, exhibits a pronounced anesthetic, anti-inflammatory and antipyretic activity, reduces swelling of the joints and increases their mobility. The action of the main component is due to its negative effect on cyclooxygenase-1 and cyclooxygenase-2 and inhibition of prostaglandin biosynthesis. Artrosilene has an anti-bradykinin effect, stabilizes the lysosome membranes and inhibits the release of enzymes from them that provoke inflammation and destruction of connective tissue.
The drug has virtually no effect on the condition of the mucous membrane of the digestive tract and does not provoke a catabolic effect on articular cartilage.

When using the drug

Artrosilene in ampoules is used to eliminate acute pain in the joints and muscles. It is shown for use in:
    rheumatism;
    arthritis (rheumatoid, psoriatic, reactive, etc.);
    arthrosis of different localization;
    gout;
    ankylosing spondylitis;
    bursitis;
    osteochondrosis of the spine;
    synovite;
    tendosynovite;
    enthesopathies;
    myalgia;
    conditions after injuries and surgical interventions.

Mode of application

Drug solution Artrosilene intended for administration intravenously or intramuscularly. Treatment with the drug should be carried out in stationary conditions under the supervision of a physician.
The daily dosage of the agent and the duration of its use depend on the clinical picture and are determined by a specialist. The maximum duration of drug treatment should not exceed 3 days in a row. The contents of the ampoule must be used immediately after opening.
    Remaining after the injection of the drug can not be stored. It should be disposed of with a printed ampoule.

Cautions to treatment

The Artrosilene medicinal solution has contraindications, the list of which the patient must be familiar with before starting to use it. Drug is forbidden to be used at:
    hypersensitivity to substances in its composition;
    individual intolerance to NSAIDs;
    renal failure;
    gastric and duodenal ulcer;
    granulomatous enteritis;
    colon diverticulosis;
    aspirin bronchial asthma;
    bleeding disorders;
    pregnancy;
    breastfeeding.
Artrosilene injectable solution is not used in the treatment of children and adolescents. It can be prescribed for patients over 18 years old.
The drug should be used with caution in the treatment of elderly patients and those suffering from chronic heart failure, bronchial asthma, severe liver disease, alcoholism, hypertension, peripheral edema, anemia and sepsis.
Artrosilene injections adversely affects the speed of psychomotor reactions and concentration of attention, so during its use a person must refrain from driving a vehicle or working on potentially dangerous objects.

Adverse symptoms

Artrosilene solution for injection can lead to the development of undesirable reactions in a patient from various organs and systems. The most common side effects of the drug include:
    abdominal pain;
    ulceration of the gastrointestinal mucosa;
    nausea;
    constipation or diarrhea;
    dizziness;
    nervousness;
    cystitis;
    swelling;
    changes in blood pressure (hypertension or hypotension);
    increased heart rate;
    allergic manifestations (rash and itching on the skin, angioedema);
    increased sweating;
    violation of the menstrual cycle.
In addition to the listed reactions, side effects of the drug may manifest as reduced visual acuity, hallucinations, an increase in the size of the liver and spleen, liver failure, changes in the chemical composition of the blood, bronchospasm, laryngism, Stevens-Johnson syndrome.
    If the described effects occur, the patient should consult a doctor about the possibility of continuing treatment.

Drug combination and overdose

During the period of use of injections Artrosilene, patients should use drugs with caution with which it can enter into drug interactions.
It is undesirable to combine the injection solution with antacids, glucocorticoids, NSAIDs, methotrexate, Kolestiramine, verapamil, cefamandol, ticlopidine, heparin, spironolactone, probenecid, tramadol, peripheral vasodilators, antithrombotic preparations.
It is also not recommended to use Artrosilene injections simultaneously with oral hypoglycemic agents, lithium and ethanol-containing drugs, valproic acid and vitamin K antagonists.
Data overdose drug solution Artrosilene missing. Experts assume that exceeding the daily dose of the drug can provoke an increase in the patient's adverse reactions.

Feedback and storage conditions

The effectiveness of Artrosilene injections indicate numerous reviews of patients. People who use the medicinal solution to relieve severe pain, note its rapid analgesic ability and prolonged action (up to 12 hours).
Ampoules with medicinal liquid should be stored in a place protected from direct sunlight at an air temperature not higher than 25 ° C.

Terms of sell

You can buy Artrosilene injections without a prescription.