Quamatel tabs 20mg #28

Quamatel instruction

You can buy Quamatel here

Quamatel tablets 20 mg or 40 mg are used for:
    Treatment of erosive gastroduodenitis (inflammation of the stomach and duodenum, accompanied by damage to the mucosa), reflux esophagitis (inflammation of the lower esophagus caused by throwing the contents of the stomach into its cavity), Zollinger-Ellison syndrome (a tumor of the pancreas leading to gastric ulcer leading to ulcerative tract);
    Treatment and prevention of gastric ulcer and / or duodenal ulcer;
    Prevention of the occurrence of symptomatic ulcers associated with the use of NSAIDs or nerve stress, as well as for the prevention of bleeding from the upper gastrointestinal tract and the occurrence of Mendelssohn syndrome (ingestion of gastric contents into the respiratory tract during general anesthesia).

Proper use

The official instruction for use of tablets Quamatel recommends using it in a dose of 20 or 40 mg 1-2 times a day. The dosage, as a rule, is the same for all clinical cases (with rare exceptions), only the duration of its use differs.
Unfortunately, the composition of Quamatel for use by children has not yet been developed, which would not bring significant harm to the growing body, which implies that it is strictly contraindicated to use it in childhood.
Also in contraindications to the drug Quamatel the following categories of patients are indicated:
    Pregnant women and nursing mothers;
    Persons prone to allergic reactions to similar drugs or who have an increased sensitivity to Quamatel.
Relative contraindications (it is possible to use it under the strict supervision of a doctor in a hospital) apply only to people with liver problems (liver failure, cirrhosis, etc.).

Positive traits

If you look from the perspective of a potential buyer, the main advantages are the detailed instruction of Quamatel tablets and the price that allows you to buy it even for people experiencing financial difficulties. True, for this, you still have to visit the appropriate specialist at least once: the drug is dispensed according to the prescription and requires an individual treatment correction.
If we turn to the objective data of medical research, then the price of Quamatel is relegated to the background, and its high efficiency is compared to similar means: the success of treatment when using Quamatel exceeds analogues by almost 35%. In addition, the frequency of reported cases of side effects from its use hardly amounts to 10%, which allows us to fully consider it as the drug of choice.
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Pharmachologic effect

The active substance famoditin is one of the most powerful competitive inhibitors of H-2 histamine receptors. The main clinically significant effect of famotidine is the inhibition of gastric secretion.
    Famotidine actively reduces the production of gastric juice and the concentration of hydrochloric acid, and changes the synthesis of peptin in proportion to the volume of gastric juice.
    It does not change the transport function of the stomach, does not affect the hepatic circulation, does not affect the secretory function of the pancreas, does not affect the concentration of gastrin secreted after meals and on an empty stomach, does not affect the portal blood flow.
    After oral administration, the drug is well absorbed from the digestive tract, the maximum concentration of a substance in the plasma is observed after 1-3 hours. It is metabolized in the liver, the elimination half-life is 3-3.5 hours, it is mainly excreted unchanged by the kidneys, only an insignificant part is excreted in the form of inactive metabolites.
    In patients with severe renal failure, the half-life of the drug may be more than 20 hours.

Dosage regimen

In relapses of peptic ulcer, 20 mg 2 r / day or 40 mg are taken orally in the evening before bedtime. If indicated, the daily dosage may be increased to 160 mg. The duration of the course therapy is determined by the gastroenterologist, taking into account the severity of the symptoms and dynamics of the process. Usually it is from 4 to 8 weeks.
With reflux of gastric contents into the esophagus, drink 20 mg 2 r / day. If necessary, increase the dose by 2 times.
To prevent exacerbations of ulcerative b-ni, it is recommended to take 20 mg at bedtime.
Treatment for Zollinger-Ellison syndrome involves the use of high doses; at the initial stage of therapy, they take 20-40 mg 4 times a day, withstanding 6-hour time intervals. The maximum daily dose can be up to 480 mg.
Patients undergoing surgery under anesthesia are given 40 mg in the evening on the eve of surgery and 2.5 hours before general anesthesia in order to prevent aspiration of gastric juice. The dose for iv administration is half as much.
Parenteral Quamatel is prescribed only when it is not possible to take per os. For iv / drop or drop injection, the lyophilisate is diluted in 5-10 ml of solvent (1-2 ampoules) immediately before injection or infusion. The finished product can be stored at room temperature for no more than 24 hours; then it loses stability. Inkjet solution is administered for ≥ 2 minutes, and drip - 15-30 minutes.
The usual single dose is 20 mg, and the frequency of administration is 2 r / day with 12-hour intervals. With the diagnosed Zollinger-Ellison syndrome, injections are made 4 r / day.

Positive traits

Quamatel is a fairly new drug (by pharmacological standards), which has established itself, first of all, with high efficiency and faster, in comparison with its analogues, achievement of positive treatment results. Multiple clinical studies conducted with the consent of thousands of patients have revealed the following advantages, on the basis of which the drug can be considered the best option:
    The dose required to achieve a therapeutic effect is almost 8 times less than that of "traditional" drugs, which are used today in most clinics;
    The duration of the drug is 2-4 hours longer than its counterparts;
    Confirmed safety of long-term use: less than 1% of cases of side effects have been recorded over the entire life of Quamatel;
    The absence of violations of the liver, increased action of alcohol and alcohol-containing drugs;
    The almost complete absence of negative interaction with other drugs;
    The presence of a dosage form for parenteral use.

Side effect

From the hemopoietic system: very rarely - agranulocytosis, pancytopenia, leukopenia, thrombocytopenia, bone marrow hypo- or aplasia.
Allergic reactions: urticaria, skin rash, itching, bronchospasm, angioedema, anaphylactic shock.
From the side of the central nervous system: headache, dizziness, drowsiness, hallucinations, confusion, increased fatigue, depression, agitation, anxiety.
From the sensory organs: decreased visual acuity, tinnitus.
Dermatological reactions: alopecia, acne vulgaris, dry skin, toxic epidermal necrolysis.
Other: fever.

Indications for use

It is recommended to prescribe for the treatment of diseases of the digestive tract, the cause of which is increased secretion of gastric juice:
    Duodenal ulcers.
    Peptic ulcer of the stomach.
    Reflux gastroesophagic disease.
The use is indicated for the prevention of aspiration of gastric acid contents against the background of general anesthesia during surgical interventions and for the prevention of the development of a postprandial hyperacid state.
Also, the drug is used in the treatment of pancreatitis. The drug is acceptable for the treatment of gastralgia and heartburn, the occurrence of which is associated with increased acidity of the secretion of the stomach.

Special instructions

The purpose of the drug Quamatel in injections is an occasion to be especially careful, because in some cases it is able to hide the symptoms of stomach cancer. In this regard, before proceeding with famotidine therapy, one must make sure that there is no malignant process in the body. The appearance of withdrawal syndrome is possible in the case of a sharp withdrawal of this drug. It is necessary to slowly reduce the dosage before discontinuing the drug.
If the drug was prescribed for the treatment of a particularly weakened patient, as well as if it was indicated to a patient undergoing a stressful situation, then stomach problems of a bacterial nature and the further development of the infection are not excluded.
This drug suppresses the body's response to an irritant (histamine), which leads to false negative results. Therefore, if any diagnostic skin tests are performed, then taking Quamatel should be temporarily suspended.
During the entire treatment with Quamatel it is necessary to monitor the diet and exclude from it foods, drinks and other medications that irritate the gastric mucosa
Patients whose daily activities are related to driving a car or have a potential danger, need to be careful

Terms of sell

You can buy Quamatel without a prescription.