Omez D caps #30

Omez D instruction

You can buy Omez D here

Release form, composition and packaging

The medication is in the form of white-pink capsules. On the case you can see the omez engraving. The contents are clearly visible under the shell: white round solid granules. The composition of the tool includes the following components:
    domperidone;
    omeprazole;
    MCC;
    magnesium stearic acid;
    polysorb;
    sodium starch glycolate;
    sodium dodecyl sulfate;
    talc.
Tablets are packed individually in a honeycomb pack. The kit includes instructions for use Omez D.

Pharmachologic effect

The medication is a central blocker of dopamine receptors and a proton pump, which is effective in gastroesophageal reflux disease. The medication is used to treat peptic ulcer of the stomach or duodenum.

Pharmacodynamic action of domperidone

The component prolongs the contractility of the stomach in the output section. It helps to normalize the stool when it hardens or is absent, while the tone of the gastroesophageal sphincter increases. The substance removes lactogenic hormone from the pituitary gland. The medication blocks the gag reflex and urges. The medicine has a beneficial effect on the gastric mucosa. The substance does not cause adverse reactions, therefore Omez D is approved for use by various categories of patients without restrictions.

Pharmacodynamic action of omeprazole

The substance is an inhibitor of the proton pump in parietal glandulocyte, blocking the conversion of hydrochloric acid. At the same time, gastric secretion decreases. The medication begins a positive effect on the stomach within an hour after administration. The prolonged action lasts a day. The maximum effect is after two hours. Complete cleansing of the body of the substance occurs in four to five days.

Pharmacokinetic properties of domperidone

The substance promotes the rapid release of the stomach from feces and increases the tone of the cardiac sphincter. The component is well absorbed into the walls of the stomach after ingestion, while it is characterized by a relatively low bioavailability due to the reduced acidity of the stomach, which reduces its absorption. An hour after administration, the maximum content of the component in the blood serum is reached. After it enters the stomach, the substance is redistributed to tissues and organs through the circulatory system, while the effect on the brain tissue remains low. Metabolism occurs in the liver and intestines. The remains of the substance come out mainly with feces, about 30% is excreted through the kidneys with urine. The elimination half-life ranges from seven to nine hours. In patients with impaired renal function, the elimination half-life increases.

Pharmacokinetic properties of omeprazole

The component inhibits the effect of hydrochloric acid. After it enters the stomach, the component is rapidly redistributed through the blood to tissues and organs. The maximum content in the blood is reached one and a half hours after administration. The component has an average bioavailability at high concentrations in the circulatory system. Metabolism occurs in the liver. The elimination half-life averages about an hour. The component is excreted through the kidneys with urine. Kidney disease significantly reduces the half-life, which must be considered when prescribing the dosage and duration of the course. The elimination time of the component is also reduced in elderly patients, as well as in patients with liver failure.

Indications

Omez D is recommended for use by patients with:
    violation of the normal functioning of the upper digestive system: esophagus, stomach, part of the small intestine;
    throwing the contents of the stomach into the esophagus (gastroesophageal reflux disease).
Omez D is prescribed by the attending physician after a thorough, complete examination, determination of the clinical picture of the disease, if monotherapy does not bring positive results.

Contraindications

The drug can not be taken with:
    hypersensitivity to components;
    bleeding of the gastrointestinal tract;
    difficult bowel movements, complete blockage of the intestinal tract;
    perforated peptic ulcer;
    pituitary adenoma;
    breastfeeding.
In addition, Omez D should not be prescribed to children. With caution and under the supervision of the attending physician, the drug is prescribed to patients with kidney or liver diseases, as well as during the period of gestation.

Dosage

The product is intended for oral use. Tablets are taken daily for the time determined by the attending physician after the examination. You can not crush, break, dissolve the contents of the capsule. Omez D is swallowed whole with plenty of drinking water. The daily dosage is 2 capsules per day, unless otherwise prescribed by a doctor. Tablets are divided into two doses, taking them 20 minutes before a meal.

Side effects

Admission Omez D can cause the manifestation of adverse reactions of the body from the work of various systems of the body:
    digestive system: cramping pain in the abdomen, loose stools, difficulty defecating, vomiting, bloating, dry mouth, upset taste buds, inflammation of the epithelium of the mouth, increased levels of hepatic aminotransferase, hepatitis (with severe liver disease) , liver failure;
    nervous system: impaired motor activity, headache, vestibular disturbances, agitated state, sleep disturbances, skin sensitivity disorders, numbness of the extremities, depression, imaginary visions, brain damage;
    musculoskeletal system: weakening, muscle pain, joint pain;
    hematopoietic system: a decrease in the number and level of white blood cells, a decrease in the number of platelets, a decrease in the number of all blood cells;
    skin: rashes, itching, hypersensitivity to light, MEE, baldness;
    allergy symptoms: Quincke's edema, nettle fever, narrowing of the bronchi, immuno-inflammatory damage to the kidneys, anaphylaxis;
    other symptoms: an increase in the level of the hormone prolactin in the blood, spontaneous outflow of milk from the mammary glands, an increase in the mammary gland in men, visual impairment, swelling, hyperhidrosis, the formation of a benign gastric cyst.

Overdose

In case of an overdose, the patient exhibits characteristic symptomatic signs. Symptoms of an overdose of Domperidone:
    drowsiness, lethargy;
    vertigo, disorientation;
    motor disorders.
With the manifestation of such reactions of the body, it is necessary to do a gastric lavage, drink activated charcoal, and conduct local symptomatic treatment, which the doctor will prescribe. You may need to take antihistamines. Symptoms of an overdose of omeprazole:
    visual impairment;
    sleeping condition;
    nervous overexcitation;
    blurred consciousness;
    headaches;
    hyperhidrosis;
    dry mouth
    gagging;
    heart rhythm disturbance.
If there are symptomatic signs of an overdose, it is necessary to consult your doctor, conduct gastric lavage and local treatment.

Pregnancy

The remedy can not be prescribed to women during the period of breastfeeding, as well as when carrying a child.

Application for children

Do not take Omez D for children.

Special instructions

Before the course of taking Omez D, you need to undergo a full examination in a medical institution in order to exclude the risk of oncology, since the drug is able to block symptoms and may confuse a diagnostic analysis. Elderly patients should take Omez D with great care under the supervision of a physician, since in the elderly, the half-life is significantly reduced. In case of liver or kidney failure, the attending physician will tell you how to take Omez D. It is necessary to monitor the performance of the internal organs throughout the course of administration. According to reviews, Omez D can cause drowsiness, blurred vision, weakness, so you should refrain from driving, performing work that requires concentration.

Drug interaction

Omez D can not be taken simultaneously with a number of other drugs:
    antacids;
    anti-secretory drugs;
    anticholinergics;
    antimycotics;
    antibiotic agents;
    macrolides;
    HIV HIV;
    semi-synthetic antibiotic Ampicillin;
    iron preparations;
    Introcanazole;
    Ketokenazole;
    Diazepam tranquilizer;
    indirect anticoagulants;
    antiepileptic drug phenytoin.
When taking other medicines, it is necessary to inform the attending physician before prescribing Omez D.

Terms and conditions of storage

It is necessary to store the product in a place isolated from the reach of children at a temperature not exceeding 25 degrees. It is necessary to exclude hit of moisture or light. Shelf life in sealed form is two years from the date of manufacture.

Terms of sell

You don't need a prescription to buy Omez D.