Maalox susp mini 4.3ml #6

Instruction for Maalox

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Indications for use of the drug Maalox

Peptic ulcer of the stomach and duodenum in the acute phase;
acute gastroduodenitis, chronic gastroduodenitis with normal or increased secretory function in the acute phase;
hiatal hernia, reflux esophagitis;
dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching after errors in diet, excessive consumption of ethanol, coffee, nicotine, etc.
dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching (and their prevention), resulting from the use of certain drugs (NSAIDs, corticosteroids, etc.).

Pharmacodynamics

The drug neutralizes free hydrochloric acid without causing secondary hypersecretion of hydrochloric acid. Due to the increase in pH when it is taken, the peptic activity of gastric juice decreases. It also has an adsorbing and enveloping effect, due to which the effect of damaging factors on the mucous membrane is reduced.

Pharmacokinetics

Magnesium and aluminum hydroxides are considered topical antacids that are practically not absorbed when taken at recommended doses and, therefore, do not have systemic effects.

Use of the drug Maalox during pregnancy

In animals, there is no clear indication of the teratogenic effect in aluminum hydroxide and magnesium hydroxide. To date, no specific teratogenic effects have been identified with the use of the drug Maalox during pregnancy, however, due to the lack of clinical experience, its use during pregnancy is possible only if the potential benefit of its use for the mother justifies the potential risk to the fetus.
Avoid prescribing the drug during pregnancy in large doses and for a long time.
While taking Maalox, discontinuation of breastfeeding is not required.

Contraindications

Hypersensitivity, severe renal impairment, Alzheimer's disease, neonatal period, pregnancy.

Side effects

Nausea, vomiting, change in taste, constipation. With prolonged use in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis, impaired renal function. In patients with concomitant renal failure - thirst, decreased blood pressure, hyporeflexia.

Dosage and administration

The contents of 1-2 mini-packets are taken orally 1-1.5 hours after a meal or when heartburn occurs. If necessary, you can take an additional dose of the drug 2 hours after the previous dose. The maximum daily dose is 12 mini-packets. The course of treatment is no more than 2-3 months.
With occasional use, for example, with discomfort after errors in the diet, take 1-2 mini-packets once.
In renal failure of mild severity, the maximum daily dose is 8 mini-packets. In moderate renal failure, the maximum daily dose is 6 mini-packets.
Before opening the mini-package, gently mix its contents, carefully kneading the package between your fingers. Squeeze the contents of the package into a spoon or mouth (take the suspension without preliminary dilution).

Overdose

There is no information about an overdose of Maalox mini. The drug is practically not absorbed from the digestive tract and does not have a systemic effect, so an overdose is unlikely.
Symptoms: it is assumed that due to an overdose, an increase in known side effects is possible.
Treatment: with an overdose of magnesium preparations, infusion of fluid and forced diuresis are recommended. In case of renal failure in case of an overdose, hemodialysis or peritoneal dialysis is necessary.

Interaction with other drugs

With quinidine. With simultaneous use with quinidine, an increase in serum concentrations of quinidine and the development of an overdose of quinidine are possible.
With H2-histamine receptor blockers, propranolol, atenolol, metoprolol, chloroquine, prostacyclins, diflunisal, digoxin, bisphosphonates, ethambutol, isoniazid, fluoroquinolones, sodium fluoride, GCS (described for prednisolone and dexamethiazolone azole, indole polonazolone, indone polonazole, indone, lignonazole, indole, sodium indone, azole, azole, azole, azole, azole, acetone, indone, phenothiazine antipsychotics, penicillamine, iron salts, tetracyclines, acetylsalicylic acid (and other salicylates), phosphorus-containing food additives, fexofenadine, lansoprazole, le otiroksinom. With simultaneous administration with Maalox tablets, the absorption of the above drugs in the gastrointestinal tract decreases. In the case of a 2-hour interval between taking these drugs and Maalox tablets and a 4-hour interval between taking fluoroquinolones and Maalox tablets, in most cases this undesirable interaction can be avoided.
With salicylates. With the simultaneous administration of salicylates and the drug Maalox, the excretion of salicylates with urine increases as a result of alkalization of urine under the influence of the drug Maalox.
With citrates. The combination of aluminum hydroxide with citrates may increase plasma concentrations of aluminum, especially in patients with renal failure.

Precautions while taking Maalox

With long-term administration, a sufficient intake of phosphorus salts with food should be ensured. For an adequate selection of a single dose, it is advisable to conduct an acute pharmacological test: after the suspension is introduced through a gastric tube and then washed with 10 ml of water, the pH of the gastric juice is assessed after 1 h; if the pH is below 3.5, a dose increase is necessary.

Special instructions when taking the drug Maalox mini

If during treatment symptoms from the gastrointestinal tract persist for more than 10 days or a worsening condition is observed, then the diagnosis should be clarified and treatment should be adjusted.
The 2-hour interval between the use of the drug Maalox  and other drugs and the 4-hour interval between the use of the drug Maalox mini and fluoroquinolones should be observed.
Avoid prolonged administration of the drug Maalox  in case of impaired renal function. When prescribing Maalox mini, patients with mild to moderate renal insufficiency should carefully monitor the plasma concentrations of aluminum and magnesium, and if they increase, the drug should be stopped immediately.
Algeldrate with a low phosphate content in food can lead to the development of phosphorus deficiency in the body. Therefore, when it is used, especially for a long time, a sufficient intake of phosphates from food should be ensured.
One mini-packet of the drug contains 3.15 g of sucrose and 0.2 g of sorbitol, respectively, the maximum daily dose contains 37.80 g of sucrose and 2.4 g of sorbitol.
Despite the fact that the drug is dispensed without a prescription, it is recommended to consult a doctor before using the drug during pregnancy and lactation (breastfeeding), as well as in adolescents over 15 years of age and in patients with mild and moderate renal failure.

Influence on the ability to drive vehicles and control mechanisms

The drug does not affect the ability to drive vehicles and work with mechanisms.

Storage conditions

At a temperature not exceeding 25 ° C.
Shelf life - 36 months.

Terms of sell

You don't need a prescription to buy Maalox.