TheraFlu powder #14

Instruction for TheraFlu

You can buy TheraFlu here

Release form and composition

Dosage form - powder for oral solution: granules (soft lumps may be present) pinkish, yellowish, gray-violet and white, with the taste of wild berries (11.5 g in six-layer sachets, in a cardboard bundle 1-8, 10, 12 or 25 packets).
When the powder is dissolved in 225 ml of water heated to a temperature of 75 ± 5 ° C, a pink-violet solution is formed, opaque, with a berry odor.
Active substances in 1 sachet:
    phenylephrine hydrochloride - 0.01 g;
    pheniramine maleate - 0.02 g;
    paracetamol - 0.325 g.
Auxiliary components of TheraFlu: calcium phosphate, sodium citrate dihydrate, magnesium stearate, sucrose, acesulfame potassium, silicon dioxide, maltodextrin M100, citric acid, dye blue diamond E133 (FD&C blue No. 1), dye red charming E129 (FD&C red No. 40 ), natural cranberry flavor Durarome (861149 TD2590), natural raspberry flavor WONF Durarome (860385 TD0994).

Pharmacological properties

When using TheraFlu, anesthetic, antihistamine, bronchodilating, antitussive, antipyretic, vasoconstrictive and sedative effects are observed.

Pharmacodynamics

Phenylephrine hydrochloride helps to reduce swelling, reduce local exudative manifestations, eliminate hyperemia of the mucous membranes of the nasopharynx, sinuses, nasal cavity, and narrowing of the lumen of blood vessels.
Pheniramine maleate is characterized by a weak anticholinergic, antihistamine, sedative and antiserotonin effect, representing a blocker of H1-histamine receptors. This causes the suppression of rhinorrhea, itching of the eyes and nose, sneezing, the elimination of hyperemia of the mucous membranes and swelling, a decrease in the severity of allergic reactions, and narrowing of the lumen of the vessels.
Paracetamol is a non-narcotic analgesic and has an analgesic, antipyretic and mild anti-inflammatory effect.

Pharmacokinetics

The action of TheraFlu appears 20 minutes after oral administration and lasts for about 4.5 hours.

Indications for use

According to the instructions, TheraFlu is used for symptomatic treatment of infectious and inflammatory diseases accompanied by chills, fever, headache, pain in muscles and joints, sneezing, stuffy nose and runny nose.

Contraindications

    diabetes;
    sucrose / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption;
    alcoholism;
    portal hypertension;
    concomitant use of beta-blockers, tricyclic antidepressants or monoamine oxidase inhibitors (MAOs);
    age up to 12 years;
    period of pregnancy and breastfeeding;
    hypersensitivity to any component of the drug.

Carefully

    arterial hypertension;
    angle-closure glaucoma;
    severe atherosclerosis of the coronary arteries;
    congenital hyperbilirubinemia (Gilbert, Dubin-Johnson, Rotor syndromes);
    pheochromocytoma;
    blood diseases;
    bronchial asthma;
    glucose-6-phosphate dehydrogenase deficiency;
    severe liver or kidney disease;
    hyperthyroidism;
    prostatic hyperplasia.

Instructions for use TheraFlu: method and dosage

TheraFlu is taken orally by dissolving the contents of the sachet in a glass of hot boiled water. If desired, sugar can be added to the drink.
1 sachet = 1 dose.
Within 24 hours, no more than 3 doses are allowed. The interval between doses should be at least 4 hours.
You can take the drug at any time of the day, but the best effect is noted with evening reception (at night).
If no improvement occurs within 3 days, consult a doctor.

Side effects

    allergic reactions: urticaria, itching, skin rash, angioedema;
    nervous system: decrease in the rate of psychomotor reactions, sleep disturbance, drowsiness, increased irritability, dizziness;
    digestive system: dry mouth, stomach pain, nausea, vomiting;
    cardiovascular system: increased blood pressure (blood pressure), palpitations;
    others: urinary retention, increased intraocular pressure, paresis of accommodation.
With prolonged use of TheraFlu in large doses, there are disturbances in the blood picture (thrombocytopenia, anemia, agranulocytosis), nephro- and hepatotoxicity.

Overdose

Symptoms of an overdose are due to the presence of paracetamol in TheraFlu and are manifested when ingested more than 10-15 g of this substance. These include: loss of appetite, pain in the epigastric region, nausea, vomiting, in severe cases - hepatonecrosis, increased activity of hepatic transaminases, liver failure, encephalopathy, an increase in prothrombin time and coma.
As a treatment, it is recommended that a gastric lavage be carried out within the first 6 hours after administration, 8–9 hours after an overdose, the precursors of glutathione-methionine synthesis and SH group donors should be administered to the patient, and acetylcysteine ​​after 12 hours. Medical care is vital.

special instructions

During drug therapy, it is recommended to abandon the use of alcoholic beverages (due to an increased risk of developing a hepatotoxic effect) and refrain from performing potentially dangerous activities, including driving a car.
Do not take the drug from damaged bags.

Drug interaction

    ethanol, sedatives, MAO inhibitors: their effect is enhanced;
    barbiturates, rifampicin, carbamazepine, phenytoin, zidovudine and other inducers of microsomal liver enzymes: the likelihood of hepatotoxic effects of paracetamol increases;
    glucocorticosteroids: increased likelihood of increased intraocular pressure;
    uricosuric preparations: their effectiveness decreases;
    indirect anticoagulants: their effect is enhanced;
    tricyclic antidepressants: increased sympathomimetic effect;
    halotane: increased risk of ventricular arrhythmias;
    guanethidine: its hypotensive effect decreases, alpha-adrenostimulating activity of phenylephrine increases;
    antiparkinsonian drugs, antidepressants, antipsychotics, phenothiazine derivatives: the risk of side effects such as urinary retention, dry mouth, and constipation increases.

Terms and conditions of storage

Keep out of reach of children at temperatures up to 25 ° C.
Shelf life is 2 years.

Reviews about TheraFlu

According to reviews, TheraFlu effectively copes with the symptoms of influenza and SARS, but does not affect the causative agents themselves. Also, some patients and doctors note its negative effect on the liver. However, in situations where it was necessary to urgently improve the condition against a cold, TheraFlu proved to be good.

Terms of sell

You can buy TheraFlu without a prescription.