Tantum Verde spray 0.255mg/dose 30ml

Tantum Verde spray instruction

You can buy Tantum Verde spray here

Structure

Per 100 ml of topical spray, dosed 0.255 mg / dose
Active ingredient: benzidamine hydrochloride - 0.15 g
Excipients: ethanol 96% 10.0 ml, glycerol 5.00 g, methyl parahydroxybenzoate 0.100 g, menthol flavoring (flavoring) 0.030 g, saccharin 0.024 g, sodium bicarbonate 0.011 g, polysorbate 20 0.005 g, purified water q.s. up to 100 ml.

Pharmacodynamics

Benzidamine is a non-steroidal anti-inflammatory drug, belongs to the group of indazoles. It has an anti-inflammatory and local anesthetic effect, has an antiseptic effect against a wide range of microorganisms. The mechanism of action of Tantum Verde spray is associated with stabilization of cell membranes and inhibition of prostaglandin synthesis.
Benzidamine has an antibacterial and specific antimicrobial effect due to the rapid penetration of microorganisms through the membranes, followed by damage to cell structures, metabolic processes and cell lysosomes.
It has an antifungal effect against Candida albicans. It causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzidamine in inflammatory processes in the oral cavity, including infectious etiology.

Pharmacokinetics

When applied topically, Tantum Verde spray is well absorbed through the mucous membranes and penetrates into the inflamed tissues; it is found in the blood plasma in an amount insufficient to produce systemic effects.
Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products.

Indications for use

Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies):
Gingivitis, glossitis, stomatitis (including after radiation and chemotherapy);
-pharyngitis, laryngitis, tonsillitis;
- candidiasis of the oral mucosa (as part of combination therapy);
-calculous inflammation of the salivary glands;
-after surgical interventions and injuries (tonsillectomy, jaw fractures)
-after treatment and tooth extraction;
periodontal disease;
For infectious and inflammatory diseases that require systemic treatment, the use of Tantum Verde spray as part of combination therapy is necessary.

Contraindications

- Increased sensitivity to benzidamine or other components of Tantum Verde spray;
-children under 3 years old

Carefully

Hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including history).

Use during pregnancy and during breastfeeding

The drug Tantum Verde spray should not be used during pregnancy and during breastfeeding.

Dosage and administration

Topical spray dosed 0.255 mg / dose:
Locally, after eating. One dose (one injection) corresponds to 0.255 mg of benzidamine. Adults (including elderly patients) and children over 12 years of age with 4-8 injections 2-6 times a day. Children from 6 to 12 years old - 4 injections 2-6 times a day. For children from 3 to 6 years, 1 injection for every 4 kg of body weight, but not more than 4 injections (maximum single dose) 2-6 times a day. Do not exceed recommended dose.
1. Turn the cannula (white tube) to the “vertical to vial” position.
2. Insert the cannula into the mouth and direct it to the sore spots in the mouth or throat.
3. Press the dosing pump on the top of the bottle as many times as the doses prescribed. One click corresponds to one dose. Hold your breath while injecting.
The duration of treatment should not exceed 7 days. If after treatment within 7 days there is no improvement or new symptoms appear, it is necessary to consult a doctor. Use Tantum ® Verde spray only according to the method of application and in the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.

Side effects

Classification of the incidence of side effects of the World Health Organization (WHO):
very often - ≥1 / 10;
often - from ≥ 1/100 to <1/10;
infrequently - from ≥1 / 1000 to <1/100;
rarely - from ≥1 / 10000 to <1/1000;
very rarely - <1/10000;
frequency unknown - cannot be estimated based on available data.
In each group, unwanted effects are presented in decreasing order of severity.
Local reactions: rarely - dry mouth, burning in the mouth; frequency unknown - a feeling of numbness in the oral cavity.
Allergic reactions: infrequently - photosensitivity; rarely - hypersensitivity reactions. skin rash, itchy skin; very rarely - angioedema, laryngospasm; frequency unknown - anaphylactic reactions.
If any of the side effects specified in the instructions are aggravated, or any other side effects not listed in the instructions are noted, you should immediately inform your doctor.

Overdose

Currently, cases of overdose of the drug Tantum Verde spray have not been reported. Symptoms: when using the drug in accordance with the instructions for use, an overdose is unlikely. If the drug is accidentally swallowed, the following symptoms are possible: vomiting, abdominal cramps, anxiety, fear, hallucinations, cramps, ataxia, fever, tachycardia, respiratory depression.
Treatment: symptomatic; empty the stomach by inducing vomiting or rinse the stomach using a stomach tube (under the supervision of a doctor); provide medical supervision, supportive care, and adequate hydration. The antidote is not known.

Interaction with other drugs

No studies of interactions with other drugs have been conducted.

special instructions

When using the drug Tantum Verde spray, hypersensitivity reactions may develop. In this case, it is recommended to discontinue treatment and consult a doctor to prescribe appropriate therapy.
In a limited number of patients, the presence of ulcers in the throat and oral cavity may indicate the presence of a more serious pathology. If symptoms persist for more than 3 days, consult a doctor.
The use of the drug Tantum Verde spray is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
The drug Tantum Verde spray should be used with caution in patients with a history of asthma due to the possibility of developing bronchospasm in patients taking the drug.
Tantum Verde spray contains parahydroxybenzoates, which can cause allergic reactions.
Influence on the ability to drive vehicles, mechanisms
It does not affect the ability to drive vehicles and work with mechanisms.

Release form

Topical spray dosed 0.255mg / dose:
- 30 ml (176 doses) of the solution in a bottle of white polyethylene, equipped with a pump and pressure device with a folding cannula.
- 1 bottle along with instructions for use are placed in a cardboard box.

Storage conditions

At a temperature not exceeding 25 ° C, in a dark place.
Keep out of the reach of children!

Shelf life - 4 years.
Do not use after expiration date.

Terms of sell

You don't need a prescription to buy Tantum Verde spray.