Ascoril syrup 100ml

Ascoril syrup instruction

You can buy Ascoril syrup here

Cough is the main sign of respiratory diseases of various origins. Especially often it manifests itself with the onset of the cold season, which is characterized by chilly and damp weather. Many people think that coughing is a dangerous bronchial reflex, but its task is to save the body and restore airway patency, the lumen of which is filled with a viscous and viscous secret.
Sputum formation occurs not only in patients. According to medical research, it is also found in the bronchi and trachea of ​​healthy people. A viscous substance serves as a respiratory tract cleanser, which removes pathogenic microbes and foreign microparticles from the bronchopulmonary apparatus that get inside when a person inhals. Active exposure to viral infections leads to inflammation in the respiratory system and an increase in sputum volume, which becomes more viscous and difficult to separate and is a harbinger of unproductive cough.
Especially susceptible to dry cough are preschool children, in whom colds develop several times faster than in adults. Since the cough reflex is poorly developed in children under 6 years of age, they physiologically cannot contribute to the independent excretion of sputum from the bronchi. To do this, there are special expectorant drugs that stimulate airway motility.

Release form and composition

Ascoril syrup goes on sale in the form of a transparent sticky syrup having a specific aroma and a bright orange tint. It is contained in a brown plastic bottle, hermetically sealed with an aluminum screw cap, which is equipped with a mechanism for controlling the first opening.
Ascoril syrup includes a number of active and inactive substances. Its basis is guaifenesin, bromhexine hydrochloride and salbutamol. Additional components are presented:
    sorbitol;
    citric and sorbic acid;
    sucrose;
    purified glycerin;
    menthol;
    food supplement sodium benzoate;
    propylene glycol;
    flavorings;
    food coloring yellow.
The syrup is produced in volumes of 100 and 200 ml, attaching a measured cap of white plastic and an annotation to the bottle with syrup.

Pharmacodynamics

Ascoril expectorant syrup is a multicomponent cough medicine with an expectorant, mucolytic and anti-inflammatory effect.
Its main functional substance is guaifenesin, whose task is to reduce the surface tension of the structures of the respiratory system. It is also considered a highly productive mucolytic agent that affects the secretory cells of the bronchial mucosa, which in turn take part in the production of neutral polysaccharides. The main task of guaifenesin is to reduce the viscosity of sputum by depolymerization of acid mucopolysaccharides. Getting into the organs of the bronchopulmonary apparatus, the substance has an effect on the secretion that is difficult to separate, facilitates its passage and helps in converting into a productive cough.
Bromhexine is the active substance of the drug, endowed with mucolytic properties, which improve the expectorant effect and activate the discharge of bronchial secretions.
Another functional element of Ascoril syrup is salbutamol, which is considered a stimulant of beta-adrenergic receptors of the myometrium, blood vessels and bronchi. The function of a bronchodilator is to prevent and eliminate bronchospasm, increase the vital capacity of the lungs, and also reduce airway resistance. In this case, salbutamol does not have a negative effect on blood pressure.

Pharmacokinetics

The process of absorption of guaifenesin occurs instantly from the gastrointestinal tract. The substance is distributed into the blood and soft tissues, which contain acid mucopolysaccharides. Metabolism of more than 60% of the elements of the drug passes in the liver. The half-life of guaifenesin is about 60 minutes. Metabolites and a substance that remains unchanged are excreted from the body with sputum and urine.
Bromhexine is absorbed from the digestive system quickly and almost completely. In addition, it has low biological activity and has the ability to penetrate the placental barrier. The metabolic process occurs in the liver by demethylation and oxidation, forming a pharmacologically active ambroxol. The half-life of bromhexine varies between 14-15 hours. The substance is excreted from the human body with urine.
After oral administration, salbutamol is rapidly absorbed. It can penetrate the blood-brain barrier and 10% bind to plasma proteins. In the liver and intestinal wall, the substance undergoes a biotransformation process. The half-life of it is from 4 to 6 hours. The main part of the metabolites is excreted by the kidneys and only 4% with bile.

Indications for Ascoril exectorant syrup

Mucolytic syrup is used in the complex treatment of infectious and inflammatory diseases of the acute and chronic forms of the respiratory system. Its effective pharmacological properties allow you to fight the following ailments:
    obstructive bronchitis;
    prolonged lung diseases;
    bronchial asthma;
    pneumonia
    inflammation of the mucous membrane of the trachea, bronchi and bronchioles;
    whooping cough;
    tuberculosis
    emphysema.

Instructions for use

Ascoril syrup with bronchodilation action is intended for oral administration for children and adults. It shows a positive result in the treatment of dry cough in preschool children.
There are several dosage forms of the drug, each of which is appropriate for use in a specific age category. Most often, Ascoril cough syrup is prescribed for children under 6 years of age. Guaifenesin-based tablets are not recommended for babies to avoid the risk of exceeding the dosage. The daily rate and duration of the drug is determined by the pediatrician after an examination and diagnosis.
The standard dosage for the treatment of respiratory diseases is:
    for children under 6 years of age - 5 ml no more than 3 times a day;
    for children from 6 to 12 years old - 5-10 ml three times a day;
    for adults and children over 12 years old - 10 ml 3 times a day.
It is forbidden to take medicine on an empty stomach. It is recommended to use syrup 30 minutes after a meal. The suspension can be washed down with purified or boiled water in small quantities. However, do not use milk with soda or mineral water containing bicarbonate for these purposes. The duration of the course of treatment can vary from 5 to 7 days.

Contraindications

Ascoril expectorant syrup is prohibited for those who have a high risk of developing clinical symptoms of the following pathologies:
    hypersensitivity to drug substances;
    diabetes mellitus;
    high blood pressure;
    gastric and duodenal ulcers;
    glaucoma
    thyrotocycosis;
    heart disease;
    tachyarrhythmias;
    liver failure;
    impaired renal function.
In addition, a mucolytic agent, which includes guaifenesin, should be avoided in the treatment of bronchopulmonary diseases for pregnant and breast-feeding women.

Side effects

In most patients, treatment with a secretory drug is good. However, it is extremely rare to develop side effects, accompanied by:
    headache and dizziness;
    deterioration in well-being;
    increased excitability;
    nausea and vomiting
    diarrhea
    bronchospasm;
    tachycardia;
    allergies: skin rash, itching and urticaria.

Overdose

The main causes of overdose may be prolonged medication or the use of an increased daily dose. A patient who has violated a doctor’s prescription may feel unwell with the following clinical symptoms:
    digestive system disorder;
    arterial hypotension;
    increased heart rate;
    confusion of consciousness.
To eliminate the signs of an overdose of Ascoril syrup expectorant should interrupt the course of treatment. In addition, measures to detoxify the body should be taken and maintenance therapy prescribed, which involves taking enterosorbents.

Interaction with other medicines

To avoid the development of side effects, the simultaneous administration of a mucolytic, the active substance of which is salbutamol, with theophylline or MAO inhibitors should be excluded. It is also worth considering that bromhexine increases the absorption of antibiotics, in particular oxytetracycline, cephalexin and erythromycin into the soft tissues of the lungs.
Ascoril syrup expectorant is forbidden to use with drugs that weaken the cough reflex and medications based on codeine, which make it difficult to discharge bronchial secretions. The hypokalemic result of salbutamol can be enhanced by the combined use of an expectorant syrup with oral diuretics and glucocorticoids.

special instructions

During treatment with syrup Ascoril expectorant should take into account that the active substance guaifenesin is able to stain urine in a light pink color. Clinical studies have also shown that alkali helps to weaken the therapeutic effect of the drug, so it is not recommended to drink it with mineral or highly carbonated water.
There are no data on the negative effects of secretolytic on the fetus when taken during pregnancy. Therefore, the appointment of a medication is possible only if the expected effect for the woman exceeds the potential risk for the baby.
Ascoril syrup contains sucrose, so patients with diabetes should take mucolytic with caution, monitoring blood glucose levels. In addition, it is absolutely contraindicated for persons with hepatic or renal failure.

Terms and conditions of storage

Bronchodilating agent belongs to the category “B” medication category. Therefore, it is recommended to keep it out of the reach of children at a temperature of +8 to +25 ° C. Avoid direct sunlight on the bottle with syrup, as well as the effects of heating devices. Violation of storage rules can lead to the fact that the drug will lose its therapeutic properties and acquire dangerous qualities.
Shelf life of the drug is 2 years from the date of manufacture indicated on the cardboard packaging. It should be disposed of after the expiration date.

Reviews about the drug

In recent years, Ascoril expectorant syrup is a fairly popular secretory drug in pediatric practice. Doctors describe it as a potent and highly effective medicine that can quickly release the upper and lower respiratory tract from sputum. Syrup from a productive cough, following the doctor's prescription, is well tolerated by children. In rare cases, the development of side effects is possible, the cause of which may be individual intolerance to the components of the mucolytic.
Parents who leave comments on the forums are most concerned about the colors and flavors that make up the drug. Many people think that these substances are harmful and can have a negative effect on the child's body. Experts are in a hurry to reassure adults with the assertion that the above components are well absorbed and do not have dangerous properties.

Terms of sell

You can buy Ascoril syrup without a prescription.