Signicef 0.5% 5ml

Signicef instruction for use

You can buy Signicef here

Composition and form of release

Signicef ​​0.5% eye drops have the appearance of a clear solution with a light yellow color. The main substance in the composition that endows the drug with medicinal properties is levofloxacin in the form of a hemihydrate. Additionally, the solution includes:
    water for injections;
    benzalkonium chloride;
    hydrochloric water;
    sodium chloride;
    hypromellose;
    sodium chloride.
The ophthalmic agent is produced in 5 ml plastic dropper bottles.

Pharmacokinetics and pharmacodynamics

Drops in the eyes of Signicef ​​belong to antibacterial drugs of the fluoroquinolone group, which are used only locally. The active substance blocks the basic vital processes of the pathogens. It suppresses the activity of DNA gyrase, disrupts the process of transformation and replication of bacterial RNA. Levofloxacin has a more destructive effect on the flora, which is in the division phase.
The drug is active against many types of pathogenic and opportunistic bacteria, such as:
    proteas;
    salmonella;
    staphylococci;
    klebsiella;
    streptococci;
    campylobacter;
    chlamydia;
    Pseudomonas aeruginosa and Escherichia coli;
    shigella.
After instillation, levofloxacin accumulates in the tear film. Its level quickly reaches its maximum concentration, which is detrimental to pathogens of eye diseases and lasts for at least 5 hours. The average level of the active substance in the blood is observed after 1 hour, the maximum is 4 days after application for 2 days every 2 hours.

Indications and contraindications for use

Ophthalmic drops are prescribed for the following indications:
    treatment of diseases of the organs of vision in infectious and non-infectious processes;
    preventive use after surgical, laser operations in order to prevent complications of an inflammatory nature.
Also, drops are effective for blepharitis, conjunctivitis, keratitis. The drug Signicef ​​is prohibited to use when:
    pregnancy;
    hypersensitivity of the body to the components of the drug, including to other drugs from the quinolone group;
    breastfeeding;
    under 1 year of age.
The medication is used with caution in children and adolescents under 18 years of age.

Instructions for use

Before instillation, the bottle must be warmed in the hands, as cold drops can cause discomfort in the eyes. To drip the solution, you need to pull the lower eyelid with your finger and inject the required number of drops into the conjunctival sac, that is, under the lower eyelid. For an even distribution of drops, you need to blink quickly several times. If a person wears lenses, then they are removed before instillation and put on 20 minutes after.
Regardless of age (excluding children under 1 year old), during the first 2 days, 1 - 2 drops are instilled into the affected eye every 2 hours, a maximum of 8 times a day. From 3 to 5 days, 1 - 2 drops are also administered, but up to 4 times a day. The duration of treatment is about 5 days, the exact duration of treatment is determined by the ophthalmologist.

Side effects

Adverse reactions occur on average in 5% of people out of 100 who have used the drug. Most often, side effects appear in the form of:
    mucous cords;
    swelling of the eyelids;
    blepharitis;
    pain in the eye;
    mucous discharge;
    contact dermatitis;
    papillary growths on the conjunctiva;
    burning and itching in the eyes;
    redness of the conjunctiva;
    dry eye syndrome;
    photophobia;
    discomfort in the eyes;
    deterioration of vision.
Headache, rhinitis, allergic reactions are extremely rare.

Overdose

During the existence of this remedy, no cases of overdose have been identified. The total amount of the active substance that is in the solution is very small, therefore, a toxic effect on the body, even after accidental drinking of the drug, is unlikely.
Purely theoretically, with an excessive systematic excess of the number of drops per day or prolonged use, a local allergic reaction may occur. In case of accidental instillation of excess drops, rinse your eyes with warm water.

Special instructions, drug interactions

Signicef should not be injected into the anterior chamber of the eye and subconjunctivally. If during treatment it is necessary to use other ophthalmic agents, then the interval between their use should be at least 15 minutes. If, among the prescribed funds, there is an ointment, then it is laid last.
Signicef contain benzalkonium chloride, which can change the color of soft contact lenses. Also, this substance can accumulate on the surface of the lenses and have a negative effect on the shell of the eye. Therefore, it is advisable not to wear them during treatment.
During use Signicef, do not touch the eyelids, skin with the dispenser bottle, or touch it with your fingers to prevent contamination of the solution. The manufacturer does not indicate drugs with which the use of Signicef ​​drops cannot be combined.

Storage conditions

The drug must be stored away from small children and sunlight, at a temperature not exceeding 30 ° C. It is prohibited to freeze drops. Shelf life - 2 years from the date of release of the drug, which is indicated on the package. After opening the bottle, the drops can be used for 1 month.

Reviews

Marina, 32 years old
I was prescribed Signicef ​​after laser vision correction for myopia. After the operation, there were unpleasant sensations in the eyes, sometimes pain appeared. After the instillation, it immediately became easier. The pain disappeared in about 5 minutes. There were no complications after the correction, I can't say for sure whether the drug helped me or just the operation was successful.
Dmitry, 26 years old
My little son was prescribed drops for conjunctivitis. He got sand in his eyes in the kindergarten, and in the morning his eyes turned red and hurt. Drops were instilled for 4 days, 1 drop each. The conjunctivitis was gone, there were no side effects, as well as discomfort. Therefore, we were satisfied with the tool.
Ekaterina, 26 years old
Last year, my friends went to the lake. The next day, my eyes were very inflamed, either I scratched them with dirty hands or maybe the water was dirty, I don't even know what caused the inflammation. As soon as I arrived home I immediately went to the ophthalmologist, he prescribed Signicef ​​for me. The drops, of course, are effective, they helped quickly. But there is one drawback - personally, it was inconvenient for me to bury them every 2 hours, since I am a seller and sometimes there was no time to be distracted. Although it was necessary to use it only in the first 2 days, it was still inconvenient.
Nikita, 27 years old
I was prescribed Signicef ​​drops by the ophthalmologist when I had bacterial conjunctivitis. At first, the eyes just turned red, and after a day, they began to itch and hurt. In the morning it was hard to open my eyes, because they were stuck together with some kind of yellow liquid. I dripped the drug for 5 days, my eyes stopped hurting on the second day. I did not notice any side effects when the drops were dripping, there were no discomfort.

Terms of sell

You can buy Signicef without a prescription.