Corneregel (Korneregel) eye gel 5% 10gr

Instruction for Corneregel

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Corneregel is a local remedy used in ophthalmology to stimulate regenerative processes.

Release form and composition

The drug is produced in the form of an eye gel 5%: easily flowing, slightly opalescent or transparent, colorless (in tubes of 5 or 10 g, 1 tube in a cardboard box).
The 1000 mg gel contains:
    Active ingredient: dexpanthenol - 50 mg;
    Auxiliary components: edetate disodium - 0.1 mg, cetrimide - 0.1 mg, sodium hydroxide - 1.01 mg, carbomer - 0.1 mg, water for injection - 945.79 mg.

Pharmacodynamics

Corneregel is a protector of the cornea and stimulates the processes of its regeneration.
Dexpanthenol - the active ingredient of Corneregel, is a precursor of pantothenic acid. Thus, the substance has biological properties similar to those of D-pantothenic acid, which, after being converted in the body into coenzyme A, takes part in many metabolic processes.
According to the data obtained as a result of studies on animals, the use of the drug helps to increase the proliferation of fibroblasts and has a regenerating effect. Dexpanthenol, when applied topically, can compensate for the increased need for pantothenic acid in damaged skin or mucous membranes.
The eye gel has a high viscosity, due to which prolonged contact of the surface of the mucous membrane of the eye with dexpanthenol develops.

Pharmacokinetics

Dexpanthenol is absorbed through the skin.
Carbomer, which is part of Corneregel, has a high molecular weight, as a result of which it is not absorbed into the systemic circulation and does not penetrate into the tissues of the eyeball. The presence of this component in the composition of the drug increases the duration of contact of an aqueous solution of dexpanthenol with the corneal epithelium.

Indications for use

    Non-inflammatory keratopathy, including recurrent erosion, corneal degeneration, corneal lesions associated with wearing contact lenses (treatment);
    Stimulation of the healing process of the conjunctiva and cornea in chemical and thermal burns and injuries (as an adjunct);
    Corneal infections of bacterial, fungal or viral origin (as an adjunct).

Contraindications

A contraindication to the use of Corneregel is hypersensitivity to the components of the drug.
Due to the lack of clinical data, pregnant and lactating women should use the drug with caution.
Instructions for use: method and dosage
Eye gel Corneregel is applied topically.
The drug is instilled into the lower conjunctival sac of the affected eye 4 times a day, and also at bedtime. Single dose - 1 drop.

Side effects

During the use of Corneregel, the following side effects may occur:
    Allergic reactions: very rarely - hypersensitivity in the form of itching, skin rashes;
    Local reactions: increased tearing, pain, itching, conjunctival edema, hyperemia, feeling of a foreign body in the eye, short-term "blurred" vision.

Special instructions

In the treatment of infectious corneal lesions of bacterial, fungal or viral origin, Corneregel should not be used as monotherapy.
The preservative cetrimide, which is part of the gel, with prolonged or too frequent use, can lead to the development of local irritation of the eyes, allergic reactions (in the form of redness, burning, sensation of a foreign body in the eye) and damage to the corneal epithelium.
Wearing contact lenses during the use of the drug is not recommended, which is due to the possible incompatibility of individual components of the drug with the material from which the lenses are made. However, in cases where their wearing is still indicated, the lenses must be removed before using the eye gel Corneregel. You can put them on again no earlier than 15 minutes after the end of the procedure.
The gel tube must be closed after each use. Do not touch the eye with the pipette tip of the tube.
If there is no improvement in the condition or the development of signs of eye irritation, it is necessary to cancel therapy and seek medical advice.

Influence on the ability to drive vehicles and complex mechanisms

After instillation of Corneregel, a thin film may form on the cornea, which can lead to a short-term "blurred" vision and, accordingly, a decrease in the reaction rate. Therefore, you can start driving vehicles only after full restoration of vision clarity.

Application during pregnancy and lactation

According to the instructions, Corneregel should be used under medical supervision during pregnancy / lactation.

Drug interactions

The incompatibility of Corneregel with other drugs has not been confirmed.
When carrying out additional local therapy with eye ointments or drops, a break between their use of at least 15 minutes must be observed. In this case, Corneregel is recommended to be used last, which is due to the fact that it can lengthen the residence time of other ophthalmic drugs in the eye and, accordingly, enhance their effect.

Terms and conditions of storage

Store in a dark place, out of reach of children, at temperatures up to 25 ° C.
Shelf life is 2 years.
After opening the tube, the drug must be used within 45 days.

Reviews

In most reviews of Corneregel, patients note that the drug is highly effective, it restores and moisturizes the mucous membrane of the eye, and promotes rapid healing of corneal injury. The gel is generally well tolerated without causing any discomfort or irritation to the eyes. The main disadvantages of the drug are considered its high cost and short shelf life after opening the tube.

Terms of sell

You can buy Corneregel without a prescription.