Deplatt tabs 75mg #28

User manual for Deplatt 75

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Release form, composition and packaging

Deplatt 75 is available in tablet form. As indicated in the instructions for use for Deplatt 75, the preparation is pink, round and smooth in structure, contains an active ingredient called Clopidogrel hydrogensulfate. Milk sugar, MCC, mannitolum, hydroxypropyl cellulose, macrogolum, hydrogenated Castor Oil, E572, silicii dioxydum colloidale are used as additional ingredients. The shell of the film contains hypromellosum, E172, E171, macrogolum.

pharmachologic effect

An antiplatelet drug, like its analogs, has the following properties: • reduces the binding of a nucleotide consisting of adenine, ribose, and two phosphoric acid residues to receptors; • violates the union of platelets; • does not affect the activity of phosphodiesterase. The slowdown in aggregation is manifested already 120 minutes after taking the minimum dosage of the drug in the amount of four hundred milligrams. To achieve the maximum effect, you need to use the product from four to seven days. In Moscow, Deplatt 75 will be sold with home delivery.

Indications

The drug is prescribed to patients to prevent the development of thrombotic complications caused by one of the diseases: • damage to the heart muscle, provoked by an acute disturbance of its blood supply due to thrombosis of one of the arteries of the heart by an atherosclerotic plaque; • acute disturbance of cerebral circulation; • blocking of blood flow of peripheral arteries. As indicated in the official description, the drug is also prescribed in combination with acetylsalicylic acid. This pharmacological combination helps prevent thrombotic complications caused by ST segment elevation, as well as during surgery with stent placement. Deplatt 75 helps to avoid complications (thrombotic and thromboembolic) that can provoke AF or acute cerebrovascular accident with the subsequent development of severe neurological symptoms. You can take the medication only according to the testimony of a specialist.

Contraindications

The drug is not prescribed to patients in the following cases: • with diagnosed hypersensitivity to one of the constituent components; • when detecting violations of one or more functions of the liver, resulting from damage to its parenchyma; • contraindications also include acute bleeding; • persons under the age of majority; • with GGM syndrome. The agent is used with caution in case of an increased tendency to bleeding, moderate liver failure, impaired function of the CYP2C19 isoenzyme caused by a hereditary factor.

Method of administration and dosage

Deplatt 75 is intended for oral use. Typically, for myocardial infarction, ischemic stroke or blockage of the blood flow of peripheral arteries, seventy-five milligrams of the active ingredient is prescribed, this amount should be taken once a day. With myocardial infarction, the course of treatment can be carried out from the first to the thirty-fifth day. After ischemic stroke, the drug is prescribed from the seventh day. The maximum treatment period in this case will be six months. When clinical signs or symptoms appear that indicate unstable angina pectoris or acute myocardial infarction with or without elevation of the ST segment, the drug is recommended to be taken once in an amount of three hundred milligrams, after which the dosage is reduced to 75 milligrams. The effect of the treatment appears after ninety days, but to consolidate the result, it is necessary to take the medication for about a year.

Pregnancy and lactation

During the period of gestation and breastfeeding, taking the drug is contraindicated.

Side effects

Deplatt 75 can provoke the development of various undesirable reactions from the following body systems: 1. The hematopoietic organs can respond with a decrease in the number of platelets, leukocytes, an increase in the eosinophil count, anemia. 2. Cases of anaphylaxis and serum sickness have been reported. 3. The nervous system reacts with dizziness, sensory disturbances, hallucinations. 4. Hemorrhage into the organ of vision can provoke treatment with an antiplatelet agent. 5. Violations of the cardiovascular system are manifested by a decrease in blood pressure, severe bleeding. 6. The respiratory system reacts with pulmonary or nosebleeds, narrowing of the bronchi, provoked by muscle contraction, hemoptysis. 7. The gastrointestinal tract often responds with epigastric pain, diarrhea, bleeding, gastritis, increased gas production, urge to vomit, hepatitis. 8. On the skin, a rash is often formed, edema, itching, eczema, lichen (red flat) appear. 9. Among other reactions, bleeding at the injection site, a painful condition accompanied by fever and chills, is also distinguished.

Overdose

Failure to follow the doctor's recommendations can lead to problems with stopping bleeding, as well as other hemorrhagic disorders. In this case, the treatment is symptomatic.

Drug interactions

Reviews to Deplatt 75 confirm that the active substance, in combination with non-steroidal anti-inflammatory drugs, can provoke bleeding in the digestive organ. Acidum acetylsalicylicum enhances the action of the drug, aimed at preventing thrombus formation.

Special instructions

The drug is prescribed with caution to patients with a history of liver dysfunctions, especially in the presence of the likelihood of developing diathesis in a hemorrhagic form. Clinical studies have not confirmed its genotoxic and carcinogenic properties. Clopidogrel hydrogen sulfate does not affect the ability to drive complex mechanisms or vehicles.

Storage conditions and periods

The drug should be stored in a room protected from direct sunlight and a temperature not exceeding 30 degrees. The shelf life, if all conditions are met, is 36 months.

Terms of sell

You can buy Deplatt 75 without a prescription from a doctor.