Bravadin tabs 5mg #56

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Bravadin instruction

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The active ingredient belongs to the class of if-channel inhibitors. Bravadin was discovered in 1980 in Servier. Scientific trials on twenty thousand patients have shown that the active ingredient is effective in the treatment of heart failure and cardiac ischemia. It is easily tolerated by the body and is characterized by safety and quality indicators.

Pharmacological properties

Bravadin is a drug that slows down the heart rate, at which time the if-channels are inhibited. By suppressing the if current, the heart rate decreases, the workload on the heart decreases. Myocardial perfusion is normalized. The medicine has no toxic effect on the body. In the course of the therapy, the effectiveness in the treatment of heart diseases has been soaked. After oral administration, Bravadin is well absorbed in the gastrointestinal tract. The maximum concentration occurs sixty minutes after taking on an empty stomach. Bioavailability is forty percent, it is obtained by primary passage through the hepatic system. Food increases the time to obtain the bioavailability of the drug. When taken with food, availability is thirty percent in sixty minutes. The active ingredient binds to plasma proteins up to seventy percent. The main metabolic processes occur in the hepatic system and in the intestines under the influence of oxidative processes. The period of elimination from the body begins after two hours and is seventy percent in relation to the concentration and time in plasma. Excretion of decay products occurs equally through the excretory and digestive systems. Complete elimination from the body occurs in eleven hours. Only four percent is displayed unchanged. In patients of retirement age, the bioavailability of Bravadin does not differ from patients of younger age. Individuals with impaired liver or kidney function have twenty percent more metabolites than healthy patients. It is worth paying attention to the fact that the drug is not effective for arrhythmias. During drug therapy, it is necessary to monitor blood and heart parameters. The drug affects the activity of the retina, but this effect appears if the patient has been using the drug for a long time (more than twelve months). One of the components of the drug is lactose, therefore, the drug is not recommended for people with intolerance to this component. In the course of medical observations, it was found that while taking the medicine, you can drive a car. But in persons who have used the drug for a long time, visual acuity changed and the ability to drive a machine changed. The active ingredient can temporarily change the perception of light (this aspect is important for patients who drive vehicles at night).

Composition and form of release

The medicine is available in the form of tablets for oral administration. The composition of Bravadin includes the active components ivabradine hydrobromide and auxiliary components. The dose of ivabradine is 5 or 7.5 milligrams. The medicine is available in fourteen or fifteen tablets along with instructions for use.

Indications for use

Indications Bravadin - treatment of pain in the chest due to myocardial ischemia (angina pectoris), chronic heart failure, with sinus rhythm and heart rate below seventy beats per minute.

Side effects

Side effects of Bravadin: impaired visual acuity, hearing loss, disruption of the heart and blood vessels, headache, dizziness, fainting, shortness of breath, shortness of breath, urticaria, Quincke's edema, rash, itching or burning, decreased performance, changes in blood counts (decrease creatinine). If you suspect a side condition, you must cancel the appointment and seek help from a qualified medical professional for symptomatic therapy.

Contraindications

Contraindications Bravadin: increased sensitization to the constituent components, children under eighteen years of age, pregnancy and breastfeeding. It is not recommended to take with a decreased heart rate, after a heart attack, with severe low blood pressure. It is not prescribed for persons with hepatic and renal pathology, with heart failure, with blockages, with lactase deficiency.


Application during pregnancy

While waiting for the baby and lactation, the medicine is contraindicated. Bravadin causes toxicity in a pregnant woman's body and is unsafe to take. During lactation, the active ingredient penetrates into breast milk, if a woman needs drug therapy, then she needs to consult a gynecologist about stopping lactation.

Method and features of application

The drug is taken orally. The dosage of the drug is individual, depending on the type of pathology of the heart and blood vessels. It is taken twice a day. The interval should be twelve hours, so it is best to consume in the morning and evening with breakfast and dinner. The dosage during therapy is adjusted by the physician. The medicine was created for admission in patients from the age of eighteen; in children, the effectiveness has not been tested. In patients with impaired liver and kidney function, a minimum dosage is prescribed, which is adjusted during therapy. In patients over sixty-five years of age, therapy begins with a minimum dosage. After one calendar month, the treatment is corrected. Electrocardiogram monitoring should be performed in all patients.

Alcohol compatibility

The active ingredient cannot be combined with alcohol. Alcohol changes the heart rate, leads to side effects, worsens the course of diseases.

Interaction with other medications

It is not recommended to combine the medicine with drugs that lengthen the time interval of depolarization of the ventricles of the heart. Do not combine with antiarrhythmic drugs, they lead to changes in the work of the heart. Thiazide or loop diuretics interfere with the pharmacological properties of the drug. Do not combine reception with isoenzyme inhibitors (antifungal azoles, macrolide antibiotics, HIV inhibitors). During therapy, it is required to inform the doctor about all drugs that are already used to treat patients. It is not advisable to use the medicine together with grapefruit juice, the juice significantly increases the plasma concentration of the active substance (it can cause an overdose).

Overdose

If Bravadin's instruction is changed during admission, an overdose may develop. It can be in the form of heart rhythm disturbances. If you suspect an overdose, consult a doctor immediately. The doctor will carry out symptomatic treatment, which is required in a hospital setting.

Storage conditions

The medicine is stored at a temperature not exceeding twenty-five degrees, without access to sunlight. Have limited accessibility for toddlers. The shelf life is thirty six months.

Terms of sell

You don't need a prescription to buy Bravadin.