Terbinafine tabs 250mg #30

Terbinafine user manual

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The drug is well accumulated and retained in the nail, so its effect lasts for months, respectively, the therapeutic effect lasts a long time.

Composition

Terbinafine tablets contain the active substance terbinafine hydrochloride, as well as additional components: MCC, lactose monohydrate, potato starch, talc, primelloza, aerosil, magnesium stearate.
Clinico-pharmacological group: antifungal drug.

What helps Terbinafine?

Terbinafine tablets are used for diseases such as:
    Onychomycosis (fungal infection of the nails);
    Candidiasis of the skin and mucous membranes;
    Epidermofitiya different skin areas;
    Trichophytosis.

pharmachologic effect

According to the instructions, Terbinafine can have a therapeutic effect on a wide range of fungal infections that cause diseases of hair, nails, skin, including dermatophytes (T.rubrum, T.tonsurans, T.mentagrophytes, T.violaceum, T.verrucosum, Microsporum) as well as yeast-like fungi Candida (for example, Pityrosporum, Candida albicans) and pathogens of multi-colored lichen.
    When taking terbinafine, the substance is almost completely (99%) bound to blood proteins, which transport the drug to organs and tissues. Eating does not affect the absorption and effect of the drug. Terbinafine is absorbed by half from the administered dose after 45 minutes, and comes to the skin and nails after 4 hours and 30 minutes.
Due to the high affinity of terbinafine with the structures of the skin, hair and nails, the drug accumulates in them, and has an antifungal effect. The slowest concentration of the drug accumulates in the nails.

Instructions for use

For those who use Terbinafine, the instructions for use indicate that the duration of the course of treatment and the dosing regimen are set individually and depend on the localization process and the severity of the disease.
The average dosage for tablets for adults:
Usual dose: 250 mg once a day.
    Fungal infections of the skin: the duration of treatment for interdigital, plantar or sock-like localization of the infection is 2-6 weeks; with mycoses of other body parts: legs - 2-4 weeks, torso - 2-4 weeks; for mycosis caused by Candida fungi - 2-4 weeks; with mycoses of the scalp caused by fungi of the genus Microsporum - more than 4 weeks.
    Onychomycosis: the duration of therapy is on average 6-12 weeks. If the nails of the fingers and toes are damaged (except for the big toe), or when the patient is young, the duration of treatment may be less than 12 weeks. With an infection of the big toe, a 3-month course of treatment is usually sufficient.
As a rule, a decrease in the severity of clinical manifestations is observed in the first days of treatment. With the occasional use or premature discontinuation of therapy, there is a risk of renewed infection. If improvement does not occur after 1-2 weeks of treatment, it is necessary to verify the diagnosis.

Contraindications

Absolute contraindications for tablets:
    chronic renal failure (creatinine clearance <50 ml / min);
    acute or chronic liver disease;
    breastfeeding period;
    children's age up to 3 years (body weight up to 20 kg);
    lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
    hypersensitivity to the main or auxiliary components of the drug.

Side effects of Terbinafine

Tablets have certain side effects:
    On the part of the digestive system: nausea, vomiting, diarrhea, loss of taste, indigestion, heaviness in the stomach. Severe abnormal liver function is also possible;
    Skin: urticaria, itching, peeling;
    From the side of blood-forming organs: thrombocytopenia, agranulocytosis;
    Of the nervous system: headache, dizziness, in rare cases of depression;
    Reproductive system disorders: menstrual disorders, erectile dysfunction.

Reviews

Irina
My husband had nail fungus from the army (over 20 years), the nails were terrible. But her husband does not like pills and was afraid to drink them, treatment with folk remedies did not help.
He found Terbinafine according to reviews on the Internet and drank it, but not more than a month, he quit. What was his surprise when good nails began to grow!
Albert
Recently struggled with such a scourge, like a fungus on his legs. It was not an easy struggle! Used several drugs. Local preparations helped, but the restoration of the nail went slowly. The nail is still sick and exfoliated. Then he began to drink pills Terbinafine Israeli production. He was prescribed to me by a dermatologist. Drink should be 2-3 months. Therefore, it was important for me that the price of treatment was affordable. But I also wanted to buy high-quality medicine. Terbinafine was such a medicine. Value for money here perfect! For six weeks the nail plate has recovered. The treatment was relatively inexpensive. Good pills, but I hope I don’t need them anymore.

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