Ornidazole tabs 500mg #10

Instruction for Ornidazole

You can buy Ornidazole on this page

Of the simplest to Ornidazole are Giardia, Trichomonas, Gardnerella, pincers, ureaplasma, dysenteric amoeba. The drug has a detrimental effect on fuzobakterii, bacteroids, Clostridium, anaerobic cocci, Helicobacter.
Ornidazole, acting on bacteria, changes their DNA, which subsequently prevents microorganisms from multiplying, the drug also has a toxic effect on microbes, disrupts their respiratory processes, causing death.

Release form and composition

Tablets, film coated, round, biconvex, white or almost white color, blister of aluminum foil / PVC, cardboard packaging.
    The drug contains the active ingredient: ornidazole.
    Additional ingredients: corn starch, povidone, MCC, sodium carboxymethyl starch, magnesium stearate, titanium dioxide, hydroxypropyl methyl cellulose, talc and others.

Pharmacological effect

Ornidazole, a derivative of 5-nitroimidazole, is an antiprotozoal and antimicrobial agent. The mechanism of its action consists in the biochemical reduction of the 5-nitro group by the intracellular transport proteins of the simplest and anaerobic microorganisms. The recovered 5-nitro group interacts with the microorganism DNA cells, inhibits the synthesis of their nucleic acids, as a result of which bacterial death occurs.
The drug is active against the following microorganisms:
    anaerobic cocci: Peptococcus spp., Peptostreptococcus spp .;
    obligate anaerobes: Clostridium spp., Fusobacterium spp., Bacteroides spp. (including Bacteroides vulgatus, Bacteroides thetaiotaomicron, Bacteroides ovatus, Bacteroides distasonis, Bacteroides fragilis);
    Entamoeba histolytica, Giardia lamblia (Giardia intestinalis), Trichomonas vaginalis.
Aerobic microorganisms are not sensitive to ornidazole.

Indications for use

Only a parasitologist is competent to prescribe the treatment of a parasite with a drug like Ornidazole. And the main indications for this method of treatment are infectious diseases that are provoked by pathogens and bacteria, namely:
    amebiasis;
    Giardia;
    trichomoniasis;
    demodicosis;
    bacterial vaginitis;
    ureaplasmosis
In addition, Ornidazole is an excellent prophylactic during operations on the large intestine and internal organs in the field of gynecology. The bactericidal effect of the drug component is appropriate in the treatment of gastric and duodenal ulcers.

Contraindications

Before you begin a course of drug treatment, it is useful to look at the instructions to get acquainted with the list of contraindications to its use.
So, Ornidazole can not be treated:
    Children under the age of three;
    Women during the first three months of pregnancy and lactation;
    People suffering from multiple sclerosis, epilepsy and other diseases of the central nervous system;
    People who have an individual intolerance to one of the components of the drug.
With caution and under strict medical supervision, Ornidazole can treat people:
Old age;
    Alcohol addiction;
    With diseases of the liver and blood-forming organs;
    Working with dangerous machinery and mechanisms.

Use during pregnancy and lactation

Ornidazole is contraindicated in the first three months of carrying a child, it is also undesirable at a later time, but a drug may be prescribed to a pregnant woman if the expected effect is many times greater than the risk for the baby.
If there is a need to prescribe a drug during the breastfeeding period, breastfeeding is suspended and resumed only after 48 hours.

Dosage and method of use

The instructions for use indicate that Ornidazole tablets are taken orally, after meals, with water (a small amount).
With the frequency of the reception twice a day, take the pills in the morning and evening, with the frequency of the reception once a day - in the evening.
Recommended dosing regimen:
    Intestinal amebiasis: adults and children weighing> 35 kg - once 3 pieces. in a day; weighing> 60 kg - once 4 pcs. per day at a time; the dose for children aged 3 years and weighing from 20 to 35 kg is set on the basis of the calculation - 0.04 g per 1 kg of body weight per day at a time. Duration of treatment - 3 days;
    Trichomoniasis: adults and children weighing> 35 kg - 1 pc. 2 times a day. In order to eliminate re-infection the same course of therapy must be given to the sexual partner; the dose for children weighing from 20 to 35 kg is determined on the basis of a calculation of 0.025 g per 1 kg of body weight per day. The duration of treatment is 5 days;
    Giardiasis: adults and children weighing> 35 kg - once 3 pieces. in a day; the dose for children aged 3 years and weighing from 20 to 35 kg is set on the basis of the calculation - 0.04 g per 1 kg of body weight 1 time per day. The duration of treatment is 1–2 days;
    Extraintestinal amebiasis: adults and children from 12 years old - 1 pc. 2 times a day; the dose for children aged 3 years and weighing from 20 to 35 kg is determined on the basis of the calculation - 0.04 g per 1 kg of body weight 1 time per day. The duration of treatment varies from 5 to 10 days;
    Prevention of anaerobic infection during operations: 1–2 pcs. 1–2 hours before surgery and 1 pc. 2 times a day for 3-5 days after it.

Side effects

Possible disorders of the digestive tract:
    The appearance of pain in the head and the epigastric region;
    Feeling of dryness;
    Nausea and vomiting;
    Constipation and diarrhea;
    Taste of metal in the mouth;
    Disturbance of taste.
Possible disorders of the nervous system:
    Dizziness;
    Change of coordination;
    Trembling limbs;
    Convulsive reactions;
    Fatigue and sleepiness;
    Tension of the occipital muscles;
    Confused consciousness.
Possible changes in blood formation:
    Leukopenia;
    Neutropenia.
Possible allergic reactions:
    Itchy skin, urticaria;
    The occurrence of angioedema.
Dry mouth is a very unpleasant feeling, to get rid of it, read the article: dry mouth - causes and treatment.

Overdose

In cases of overdose, undesirable symptoms may appear in the form of epileptiform seizures, depression and peripheral neuritis.
This is carried out symptomatic treatment.

special instructions

Care must be taken in patients with diseases of the central nervous system (epilepsy, multiple sclerosis). There is a certain risk in patients with diseases of the liver, brain, alcohol abuse, pregnant and nursing mothers and children, especially when the dose is exceeded.
Research on the effect of the drug on the ability to drive and work with complex mechanisms was not carried out, but taking into account the possible development of side effects from the nervous system (including dizziness, impaired coordination of movements) during the period of drug treatment should refrain from driving and from occupations by other types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

Drug interactions

Unlike other nitroimidazole derivatives, ornidazole does not inhibit aldehyde dehydrogenase and therefore is not incompatible with alcohol. Ornidazole enhances the action of coumarin oral oral anticoagulants, which requires an appropriate correction of their dose.
Ornidazole lengthens the muscle relaxant effect of vecuronium bromide.

Reviews

We picked up some reviews of people using the drug Ornidazole:
Irina
    Taked Ornidazole 5 days to 2 tab. After the end of taking the pills, the third day is dizziness, especially in the mornings, dull eyes, nausea, sour taste in the mouth in the mornings and a slight plaque on the tongue. The state is disgusting. I hope it will end soon :)
Alina
    The drug was prescribed to me by the doctor after I had giardiasis. I had to take two days for 1.5 g of medicine at a time after eating for the night. Saw three pills at once. A few days later I passed the analysis, then another. The result was very surprised and pleased at the same time - lamblia was not found in me anymore. Thanks to my doctor and of course Ornidazole!
Regina
    A doctor prescribed Tiberal to treat giardiasis in a child, but I did not want to overpay for the brand, so I decided to buy Ornidazole. There is no difference between them: the active component is the same as the composition. They drank a pill for the night, repeated after 2 weeks. The test results are excellent, there are no parasites, and side reactions too.

Terms of sell

You don't need a prescription to buy Ornidazole.