Nemozole tabs 400mg #5

Nemozole user manual

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Release form and composition

Anthelmintic agent is available in the form of tablets and suspensions for oral administration.
There are 2 types of Nemozole tablets:
    Chewable tablets. Each contains 400 mg of albendazole, potato starch, sodium lauryl sulfate, talc, crospovidone, anhydrous silica, citric acid, pineapple flavor, magnesium stearate. Tablets are packaged in blisters of 1 pc. or cardboard boxes of 1000 pcs.
    The tablets covered with a soluble film. Each contains 400 mg of albendazole, potato starch, starch glycolate, dehydrated silica, titanium dioxide, isopropanol, talc, gelatin, propyl paraben, cellulose powder. Tablets are packed in contour cells of 1 pc. Cardboard box includes 1 blister and instructions.

Pharmacological properties

Nemozole has the following effects on worms:
    inhibits beta tubulin polymerization, reduces the activity of the cytoplasmic system of intestinal cells of parasitic worms;
    violates the course of metabolic processes (prevents the absorption of glucose);
    blocks the transport of secretory elements and other components in the muscle cells of the worms, which leads to the death of parasites.
The most sensitive to albendazole are the larval forms of the echinococcus, the pork tapeworm, the acne intestinal.
    The active substance is slowly absorbed by the intestinal walls, not detected in the blood unchanged.
In the liver, albendazole is converted to a pharmacologically active metabolite - albendazole sulfoxide. The greatest amount of this compound in the blood is detected after 5 hours. It penetrates certain tissues and fluids of the human body. In high concentrations, the drug accumulates in the worms cysts.
Albendazole leaves the body in the form of metabolites in the urine. The half-life takes 12 hours.

Indications for Nemozole

The drug is used to treat:
    parasitic lesions caused by pig larvae;
    Echinococcosis of the liver, lungs and abdominal wall caused by the larvae of canine parasites;
    nematodoses (ascariasis, hookworm, enterobiosis, trichocephalosis, opisthorchiasis, strongyloidosis)
    parasitic invasions caused by simple organisms (giardiasis, microsporidiosis);
    mixed worm infestations;
    Echinococcus cysts (before and after surgery to remove formations).

Contraindications for Nemozole

The drug does not apply to:
    individual intolerance to albendazole or other benzimidazole derivatives;
    children age (up to 6 years).
With care Nemozole is accepted at:
    violation of the functions of the blood;
    liver failure;
    cirrhosis of the liver;
    cysticercosis, accompanied by lesions of the retina.

What caused the effectiveness of the drug Nemozole

Nemozole contributes to the death and elimination from the body of both mature worms and larvae, with which it is associated with its high efficiency.

How to apply Nemozole

Suspension taken with food. All family members should be treated at the same time. Tablets are taken after meals with water. Compliance with special diets and taking laxatives is not required.

How to give children

The dosage of Nemozole depends on the type of worm infestation:
    Neurocysticercosis and echinococcosis. A single dose is set at the rate of 8 mg / kg. The drug is given to the child 2 times a day. Treated for 28-30 days. If necessary, treatment is carried out again.
    Giardiasis. The child is given 10 mg / kg of albendazole per day. The treatment lasts a week.
    Toksokaroz. The recommended daily intake is 20 mg / kg. It is divided into 2 applications. The duration of the therapeutic course is 1-2 weeks.
    Enterobiasis, ascariasis, hookworm. Daily dose - 0.2 g. The course of treatment lasts 3 days; if necessary, repeat it after 21 days.

Use by adults

Dose for adults is calculated depending on the type of disease:
    Neurocysticercosis and echinococcosis. 400 mg of albendazole taken 2 times a day. The daily dose should not exceed 800 mg. With a body weight less than 60 kg, a single dose is 200 mg.
    Toksokaroz. Nemozole is taken in the 200-400 mg 2 times a day.
    Enterobiasis, ascariasis, hookworm. 200 mg Nemozole take one time. In the absence of effectiveness, after 21 days, the procedure is repeated.
    Strongyloidosis. The recommended daily dose is 400 mg. Tablets are drunk for 3 days; therapeutic cycle is repeated after 21 days.
    Giardiasis. Daily dose - 0.4 g. Impressed for 3 days.

Side effects

The following undesirable consequences may occur when taking Nemozole:
    signs of damage to the digestive system (liver dysfunction with increased liver enzymes, nausea, vomiting, pain and feeling of heaviness in the epigastric region, loose stools);
    dysfunction of the hematopoietic system (decrease in the number of leukocytes, granulocytes and platelets, anemia);
    neurological disorders (dizziness, pain in the occipital and temporal areas, sleep problems, changes in taste perception);
    skin reactions (temporary baldness, urticaria-like skin rash, pruritus);
    other side effects (fever, hypertension, renal dysfunction, allergic reactions).

Overdose Nemozole

The use of high doses of albendazole leads to increased side effects from the digestive system. First aid involves the cleansing of the stomach and the introduction of enterosorbents.

special instructions

With parasitic lesions of the nervous system, the therapeutic scheme is supplemented with glucocorticosteroids and anticonvulsants. This helps to avoid high blood pressure in the first weeks of treatment.

Use during pregnancy and lactation

Nemozole can have a negative impact on the development of the fetus, so it is not prescribed to pregnant women.
If necessary, treatment during lactation breastfeeding stopped.

Use in old age

When treating patients older than 65 years old, the possibility of liver and kidney diseases requiring dose adjustment should be considered.

Drug interactions

Taking it simultaneously with Dexamethasone and Zimetidine results in an increase in the amount of albendazole sulfoxide in the body.

Terms and conditions of storage

Tablets and suspension stored in a cool place, preventing exposure to moisture and direct sunlight.

Reviews of parasitologists and patients

Sergey Petrovich, 49 years old, Moscow, infectious diseases doctor
“Patients come to the reception with complaints of problems with digestion and poor health. Worm invasions are found in most applicants.
With the help of standard analyzes, all types of parasitic worms cannot be identified, therefore, I prescribe a wide range of efficacy to patients. These include Nemozole. It is active against most of the most common types of worms. With proper use of the drug does not adversely affect the body. The advantage of Nemozole is the ability to destroy not only adult individuals, but also the larvae of worms. ”
Oksana, 30 years old, Krasnodar
“Nemozole used to treat ascariasis in a two-year-old son. Suspension gave the child 4 times 5 ml. For the prevention of myself and my husband, I bought Nemozole tablets. We didn’t have any side effects. The child had diarrhea in the evening. Another disadvantage is the unpleasant bitter taste of the suspension, which can cause problems in the treatment of children. The analyzes made after the treatment showed the absence of helminths, therefore, the drug was satisfied. "

Terms of sell

You don't need a prescription to buy Nemozole.