Lomflox tabs 400mg #5

Instruction for Lomflox

You can buy Lomflox on this page

Composition and release form

Medical drug Lomflox has a single dosage form - light brown film-coated tablets. On the blister is distributed on 4 or 5 pieces. The carton pack contains 1, 4 or 5 blisters, instructions for use. Features of the chemical composition:

active ingredient

lomefloxacin hydrochloride (400 mg).

auxiliary components

sodium lauryl sulfate, starch, sodium starch glycolate, propylene glycol, magnesium stearate, purified talc, colloidal silicon dioxide, crospovidone, lactose, polyvinylpyrrolidone.

shell composition

hydroxypropylmethylcellulose, methylene chloride, isopropanol, titanium dioxide.

pharmachologic effect

Lomflox is a synthetic antimicrobial agent for the fluoroquinolone group with a pronounced bactericidal action. The active component of the antibiotic blocks the DNA gyrase of the bacterium by forming a complex with its tetramer. The drug disrupts DNA replication, thereby reducing the activity of pathogenic flora, promotes the death of a microbial cell.
The antibiotic Lomflox is active against a number of pathogenic microorganisms - gram-positive and gram-negative aerobes, chlamydia, mycoplasmas, ureaplasmas, and legionella die from it. The drug has a destructive effect on microbes that are insensitive to aminoglycosides, penicillins and cephalosporins. Lomflox has a pronounced post-antibiotic effect. Streptococci (pneumoniae, groups A, B, D, G), anaerobes, Pseudomonascepacia, Ureaplasmaurealyticum, Mycoplasmahominis are resistant to lomefloxacin.
The drug is rapidly absorbed from the digestive tract. The maximum plasma concentration reaches 1–1.5 hours after oral administration of a single dose. The half-life lasts 7 hours (slow elimination from the blood occurs). The metabolites of the active substances are excreted by the kidneys. In chronic renal failure, the daily dose of Lomflox is adjusted individually.

Lomflox is an antibiotic or not?

The drug is a representative of systemic antibiotics - fluoroquinolones with antimicrobial and bactericidal action in the body. The active component of the synthetic origin of lomefloxacin hydrochloride is difluoroquinolone group, has the ability to accumulate in the tissues, reduces activity in an acidic medium.

Indications for use

Antibiotic Lomflox is characterized by a systemic effect in the body. Instructions for use contains a complete list of medical indications:
    urinary tract infections: urethritis, prostatitis, cystitis, pyelonephritis;
    infection of the upper respiratory tract: otitis media, bronchitis, pneumonia, pneumonia;
    purulent infections of soft tissues and skin;
    infection of bones and joints, for example, chronic osteomyelitis;
    pulmonary tuberculosis;
    salmonellosis, dysentery, typhoid fever, cholera;
    sexually transmitted diseases: gonorrhea, chlamydia;
    enterocolitis, cholecystitis;
    burns;
    prevention of urinary and respiratory infections;
    conjunctivitis, blepharoconjunctivitis, blepharitis (eye drops);

Dosing and Administration

Detailed instructions for using Lomflox describes the duration of drug therapy, depending on the nature of the pathological process. The medicine needs to be swallowed whole, do not chew beforehand, drink plenty of liquid. The standard dose is Lomflox 400 mg, which corresponds to 1 tablet. The number of receptions - 1 time per day. According to the instructions, the course of treatment depends on the disease:
    skin lesions - 10–14 days;
    acute chlamydia - 14 days;
    urinary tract infections - 3-14 days;
    recurrent bronchitis - 7–10 days;
    acute chlamydia, complicated gonorrhea - 14 days;
    tuberculosis - 28 days;
    recurrent chlamydia - 14-21 days.
The specified antibiotic is used to prevent infections of the genitourinary system and upper respiratory tract, before the diagnosis, planned surgery. According to the instructions for use, the patient is prescribed orally on a table. 2–6 hours before the operation or before the clinical examination. Self-medication is contraindicated.

Drug interactions

Preparations Ciprofloxacin, Pefloxacin, Ofloxacin and Lomefloxacin inhibit the growth of Mycobacterium tuberculosis when used alone (quickly absorbed into the bloodstream). While Lomflox prescribed in the scheme of complex treatment. According to the instructions, drug interaction of some pharmacological groups is not excluded:
    Antacids, sucralfat, vitamins, aluminum, iron or magnesium preparations slow down the absorption of lomefloxacin.
    In the treatment of tuberculosis, the combination of Lomflox with Rifampicin is prohibited, otherwise the risk of intoxication of the organism increases.
    Simultaneous use with Streptomycin, Isoniazid, Pyrazinamide is not prohibited.
    Cross-resistance with cephalosporins, penicillins, aminoglycosides, Metronidazole and Co-trimoxazole is absent.
    Medications that block tubular secretion, as well as Probenecid, slow down the elimination of lomefloxacin.
    The specified drug enhances the therapeutic effect of anticoagulants, increases the toxicity of NSAIDs.
    Prohibited the simultaneous use of antibiotic with alcohol.

Side effects

The drug Lomflox causes side effects that affect healthy internal organs and systems, worsen the patient's well-being. The instructions for use provide a complete list of patient complaints:
    digestive tract: nausea, vomiting, dyspepsia, dry mouth, diarrhea, constipation, change in the color of the tongue;
    nervous system: tremor of limbs, asthenia, headache, agitation, increased nervousness, asthenia, dizziness, convulsions, paresthesias;
    cardiovascular system: bradycardia, hypotension, tachycardia, extrasystole, cerebrovascular disorders, angina pectoris;
    musculoskeletal system: myalgia, calf muscle cramps, arthralgia, pain in the lower back;
    urinary system: frequent urging to the toilet, difficulty urinating, polyuria, dysuria and other disorders of the kidneys;
    skin: hyperemia of the epidermis, pruritus, swelling, photosensitization, urticaria;
    other: hot flashes to the face, increased sweating, thirst and dryness of the oral mucosa, bronchospasm, cough, impaired sputum, hypersalivation (violation of the secretion of the salivary glands).

Overdose

With the systematic excess of daily doses of Lomflox, visual hallucinations develop, limb tremor, breathing is disturbed, and convulsions occur. The patient is worried about nausea, prolonged vomiting is observed. With such symptoms, it is necessary to wash the stomach, take sorbents orally, carry out symptomatic therapy, rehydration. Hemodialysis is characterized by low efficiency. Further treatment is symptomatic.

Contraindications

Not all patients are allowed to use Lomflox. The instruction contains a list of contraindications that are not recommended to break:
    epilepsy;
    predisposition to seizures;
    gestation period, lactation;
    age up to 15 years;
    cerebral atherosclerosis;
    cirrhosis of the liver;
    hypersensitivity of the body to the active ingredients of the drug.

Storage conditions

According to the instructions for use, you need to store the medicine in a dry, dark place at temperatures up to 25 degrees. Shelf life - 3 years.

Reviews

Andrew
    Lomflox tablets with prostate, I drank a two-week course. The medicine helps a lot, it acts quickly and without side effects. Since I have chronic kidney disease, the doctor adjusted the dosage individually. It was possible to restore urination, get rid of pain and discomfort.
Anna
    She took the antibiotic Lomflox for acute cystitis. The main advantage of the drug: you need to drink a pill 1 time per day. For more I do not have enough time, and I always forget to be treated. There are no such problems with this medicine. The pain during urination passed on the third day, I still took a week course on the recommendation of the attending physician.
Sergei
    Medical drug Lomflox causes indigestion. I was prescribed for prostate, so I only suffered after starting the course. The medicine is not expensive, but I cannot judge the effectiveness. It was necessary to select an analogue as a matter of urgency, as the condition worsened on the background of attacks of diarrhea, abdominal pain and flatulence.

Terms of sell

You can buy Lomflox without a prescription.