Vizallergol user manual
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The drug has a high safety profile, therefore approved for use in children from the age of three.
Dosage Form
The drug is available in the form of eye drops in a plastic bottle, which is closed with a special stopper-dropper. The concentration of the active substance in the eye drops is 0.2%. The drug liquid itself can be from transparent to light yellow. Pharmacological effects are due to the only active ingredient, but in addition to it, several auxiliary substances are also present in the composition of the drug.
Description and composition
The main active ingredient is olopatadin. In 1 ml of its medicinal solution contains 2 mg. This substance is capable of selectively blocking histamine receptors, due to which its main pharmacological properties are manifested.
The strength of the drug is quite high, as it involves several mechanisms. Olopatadin inhibits the release of histamine, which is the main mediator of an allergic reaction and inflammation. In addition, the main active ingredient prevents the production of cytokines in the conjunctiva of the eye, which also reduces the pathogenetic development of inflammation or allergies.
The drug interacts with special cells in the conjunctiva of the eye, as a result of which the release of inflammatory mediators is inhibited. After insaling into Vizallergol’s eye, positive clinical effects were also observed in the nasal cavity, in particular, a decrease in rhinitis, edema and other symptoms that are observed in parallel with allergic conjunctivitis.
When applied topically, the drug does not affect the diameter of the pupil. A big advantage of Vizallergol is that during clinical trials no toxicity of the drug was detected for an adult, a child, as well as a carcinogenic effect on healthy cells.
In clinical trials, it was found that when taken orally, olopadadine passes into breast milk and may cause growth retardation in animals. However, when applied topically in the form of eye drops, systemic absorption is minimal, and clinically significant concentration in the blood is practically not detected.
Thus, the drug has a pronounced anti-inflammatory, antiallergic, anti-edema effect, while not affecting the adrenergic receptors, serotonin and dopamine receptors. Thanks to the selective action of Vizallergol, the course of therapy is well tolerated, and the number of side effects is minimized. After local application, the duration of action is not very high - the half-life of the drug is only 3 hours.
Indications for use
for adults
According to the official instructions for use Vizallergol has only one indication - allergic conjunctivitis. The drug can be used for both therapeutic and prophylactic purposes, when a person knows that the problem occurs seasonally in a certain period of time.
for kids
The indications for use in pediatric patients is the same as in adults — allergic conjunctivitis, including seasonal.
for pregnant women and during lactation
According to the official instructions for use, the use of the drug during pregnancy and breastfeeding is possible only if the potential benefit to the mother outweighs the possible risk to the baby. With systemic use of olopatadin, its toxicity to the reproductive function of a woman was detected, however, with the correct local application, this effect is leveled, since the main active ingredient practically does not enter the systemic circulation.
According to other studies, olopatadin was detected in breast milk, but studies were also carried out with oral administration of the drug. The risk of toxic effects, especially on newborns, cannot be ruled out, therefore, before using the drug, this category of patients must consult a doctor.
Contraindications
As a contraindication to the use of Vizallergol, in the official instructions only individual hypersensitivity to the active substance or to any auxiliary component is indicated.
Uses and doses
for adults
Vizallergol drops are intended only for local use in ophthalmology. Drug liquid should be instilled into the conjunctival sac of the affected eye, more often in both.
As a single dose, one drop of the drug is used. The frequency of use can be from 1 to 2 times per day, at the discretion of the doctor. The duration of treatment is set individually, depending on the dynamics of clinical improvements and the patient's condition. The course of therapy can be up to 4 months.
For elderly patients, the treatment regimen and dosage of Vizallergol is not required. When using the drug in pediatrics in patients older than 3 years, the dosage of drops is also not adjusted. If the liver and kidneys do not work, patients do not change the treatment regimen, since the systemic absorption of the drug with local use of Vizallergol drops is minimal.
Plastic bottle contains a special protective ring, which is the control of the first opening. If there is no ring in the package or it is damaged, no drops should be used.
When instillation of the drug in the eye is necessary with one hand to pull the lower eyelid, and the second click on the bottle and squeeze a drop of Vizallergol in the conjunctival sac. This should be done carefully to prevent contamination of the dropper tip and infection in the drug solution. To do this, it is necessary to bury the drug so that the vial does not touch the mucous membrane or skin. After each use, the dropper bottle must be tightly closed.
for kids
Vizallergol can be used by patients from the age of three, the dosage is not adjusted. The safety and efficacy of the drug for patients younger than 3 years has not been established and there is not enough data for this age group.
Thus, Vizallergol drops for children and adolescents should be applied one drop to each affected eye once or twice a day. The duration of therapy in this case is determined, depending on the severity of the patient's condition.
for pregnant women and during lactation
If the doctor has authorized the use of the drug during pregnancy or lactation, dosage adjustment is not required. Women in this category need to bury the medicine one drop in each affected eye once or twice a day, and it is not recommended to exceed the prescribed dose, as this increases the degree of systemic absorption and the toxic effect of the active ingredient on the child.
Side effects
Of the side effects of the official instruction warns of the possible development of local and systemic reactions. Local undesirable manifestations are possible in the form of blurred vision, burning or pain in the eyes, conjunctival hyperemia, eyelid swelling, keratitis, foreign body sensation in the eye, local discomfort, tearing. Of the systemic reactions with a significant excess of dosage, weakness, dizziness, nausea, headache, inflammatory processes in the region of the sinuses or larynx may occur.
In most cases, patients tolerate Vizallergol therapy well and do not notice undesirable manifestations. If any unexpected reactions, especially strongly pronounced, occur, it is necessary to report them to your doctor or any medical professional.
Interaction with other drugs
The study of the drug on the interaction with other drugs was not conducted. There is evidence that olopatadin does not alter metabolic processes when used simultaneously with some other ophthalmologic and means. In any case, it is recommended to observe the 15-minute interval between the application of different drugs in the area of the conjunctival sac.
special instructions
Immediately after application of the drug in the conjunctival sac, a person may have slightly decreased visual acuity. Because of this, it is recommended to refrain from driving and working with potentially dangerous machinery. After the restoration of visual clarity in the absence of adverse reactions from the nervous system, the patient can continue their activities.
Despite local use of the drug, systemic absorption cannot be completely excluded from attention. If any unforeseen reaction occurs on the background of starting treatment with Vizallergol, it is necessary to stop therapy and report them to your doctor immediately.
As an auxiliary substance, Vizallergol eye drops contain benzalkonium chloride, which often causes irritation and inflammation in the eye with increased sensitivity to this component. There are cases when benzalkonium chloride caused keratopathy. Especially attentive in this regard should be patients who use Vizallergol for a long time.
The drug may discolor contact lenses, so you should avoid the interaction of drug fluids and lenses. Prevent unwanted effects can be subject to the 15-minute interval between the instillation of the eye and putting on contact lenses.
If local use of several ophthalmic agents is necessary, it is recommended not to mix them, but to observe an interval of at least 5 minutes. At the same time, eye ointments are applied last.
Overdose
There is not enough data on overdose if the drug is accidentally swallowed. It is known that oral administration of olopatadin will exhibit high toxicity. Accidentally swallowing the whole vial will result in maximum systemic action and adverse reactions. When applied topically, overdose is unlikely.
A significant dose excess is reflected by an increase in the QT interval on the cardiogram and an increase in adverse reactions. In case of overdose, it is recommended to carry out symptomatic therapy, as well as to take drugs of the group of sorbents.
Storage conditions
The drug is stored under standard conditions. Permissible temperature range from 2 to 25 degrees. After opening the bottle, treatment can only be carried out for 28 days.
Terms of sell
You can buy Vizallergol without a prescription.
Reviews
Yuliya
I wish you all good health! But only those who suffer from allergies will understand me. Many of my reviews contain the phrase: "does not cause allergies." But for each person it is individual. But the aggravation of allergies in most people begins in the spring. After many years of observation, I realized that my exacerbation begins at the time of melting snow. And this spring everything was especially "acute" ... So much so that I had to go to an oculist. And so I was prescribed 2 medicines. One of them is Vizallergol. The description and instruction of the drug is on the Internet. I was prescribed to dig in 2 times a day for 2 weeks. And on the fifth day, I felt relieved. But the treatment was carried out as prescribed. The term of using the solution is very limited - only 28 days after opening the bottle!