Loratadine tabs 10mg #30

Loratadine instruction for use

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H1-histamine receptor blocker (long-acting). Suppresses the release of histamine and leukotriene C4 from mast cells. Prevents the development and facilitates the course of allergic reactions.
It has anti-allergic, antipruritic, anti-exudative action. Reduces capillary permeability, prevents the development of tissue edema, relieves spasms of smooth muscles.
After taking Loratadine, the antiallergic effect develops after 30 minutes, reaches a maximum after 8-12 hours and lasts 24 hours. It does not affect the central nervous system and does not cause addiction (does not penetrate through the BBB).
The maximum serum concentration is fixed after 1.5-2.5 hours (food intake slows down this process by about 1 hour). The level of conjugation with blood proteins reaches 97%. The process of biotransformation occurs in the liver. The average half-life of an unchanged substance is from 3 to 20 hours, and the active metabolite, descarboethoxyloratadine, is from 9 to 92 hours.
During the period of use of the drug, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and psychomotor speed.

Indications for use

What helps Loratadine? According to the instructions, the drug is prescribed in the following cases:
    allergic rhinitis;
    conjunctivitis;
    pollinosis (seasonal allergy to grass and tree pollen);
    hives;
    angioedema (angioedema);
    pruritic dermatosis;
    pseudo-allergic reactions;
    allergic reactions caused by insect bites;
    in the treatment of diseases involving allergic manifestations;
    food allergies.

Instructions for use Loratadine dosage

Regardless of the form taken by mouth before meals.
According to the instructions, adults and children from 12 years old are prescribed 1 tablet of Loratadine (10 mg) or 2 tsp. syrup a day.
The duration of the course is usually 10-15 days. In some cases, the duration of therapy is set individually, and may take from 1 to 28 days.
Children aged 3-12 years, it is customary to appoint 1/2 tablet of loratadine or one teaspoonful of syrup per day.
Children whose weight exceeds 30 kg, the drug is prescribed 1 tablet or 2 tsp. syrup a day.
Efficacy and safety of use in children under 1 year of age have not been reported.

Side effects of Loratadine

The instruction warns about the possibility of the development of the following side effects when prescribing Loratadine:
    In adults: headache, fatigue, dry mouth, drowsiness, nausea, gastritis, allergic reactions (rash), anaphylaxis, alopecia, abnormal liver function.
    In children: headache, increased nervous irritability, sedation.
Unwanted side effects were approximately the same frequency as with placebo.

Contraindications

It is contraindicated to prescribe Loratadine in the following cases:
    hypersensitivity to the active substance or other components of the drug,
    During pregnancy and breastfeeding,
    children's age up to 1 year.
In severe diseases of the kidneys and liver, take under the supervision of a physician. Patients with severe hepatic impairment need to lower the dose of the drug through a possible reduction in clearance (an initial dose of 5 mg per day or 10 mg every other day is recommended).

Overdose

With a significant excess of the recommended dose in patients appears cephalgia, drowsiness and tachycardia. In case of overdose, you should immediately seek qualified medical assistance.
It is necessary to wash the stomach, provoking vomiting (for this you can use ipecac syrup). Additionally enterosorbents are assigned (for example, plain or white activated carbon).

What do the reviews say?

According to reviews of doctors, Loratadine is one of the most popular antiallergic drugs of the 2nd generation. Compared with some analogues, it is cheap and is characterized by a significantly higher antihistamine activity, which is due to the higher strength of binding to peripheral receptors related to H1-type.
Experts say that the drug does not show a sedative effect, does not have a cardiotoxic effect, does not enhance the effect of ethyl alcohol, practically does not interact with other drugs and does not cause addiction.
Many adults after using Loratadine consider it an effective and affordable drug with a mild and prolonged action. It is also very convenient to use in both adults and children.

Terms of sell

You can buy Loratadine without a prescription.