Suprastin tabs 25mg #20

Instruction for Suprastin

You can buy Suprastin here

Suprastin is widely used for the treatment of allergic conditions and the treatment of inflammatory diseases of the respiratory tract in adults and children. The drug has a pronounced anti-allergic effect. Available in the form of a solution intended for intramuscular or intravenous administration. Suprastin is used to treat diseases that are allergic in nature.
The drug is prescribed to patients suffering from urticaria, conjunctivitis, dermatitis, serum sickness, eczema in acute or chronic form.

Composition and release form

Suprastin tablets have a white color, a round shape and a flat cylindrical surface. The main active component of the drug is chloropyramine, its content in one tablet is 25 mg. It also includes auxiliary substances, which include:
    Carboxymethyl starch sodium.
    Gelatin.
    Potato starch.
    Stearic acid.
    Lactose monohydrate.
    Talc.
The tablets are packaged in a blister of 10 pieces. The carton pack contains 2 blisters with pills, as well as instructions for use of the drug.

pharmachologic effect

Chloropyramine blocks specific H1 receptors. The drug is characterized by antihistamine and m-anticholinergic blocking effect, as well as moderate antispasmodic activity.
When taken per os absorption Suprastin in the digestive tract occurs quickly and in full. The action begins after 15-30 minutes, and the maximum effect is fixed after 1 hour and lasts from 3 to 6 hours.
The substance is evenly distributed in body tissues and biological fluids. It freely passes the hematoencephalic and hematoplacental barriers. Biotransformation of the active substance takes place in the liver, and it is excreted through the kidneys. Excretion of the drug in children is much more intense.

Indications for use

What helps? The indications include:
    allergy to drugs and food;
    allergic rhinitis (runny nose) and conjunctivitis;
    serum sickness;
    allergic skin rashes;
    hypersensitivity reaction with non-toxic insect bites;
    pruritus;
    atopic dermatitis;
    contact dermatitis;
    eczema.
With such a severe hypersensitivity reaction, as angioedema, the drug is administered as an injection (tablets are used as an aid).

Contraindications

The drug is contraindicated in children in the case of:
    hypersensitivity to the individual components of the drug;
    lactase deficiency and lactose intolerance;
    with acute manifestations of bronchial asthma.
The drug in the form of tablets or injections with caution is prescribed to children with eye disease, pathology of the kidneys and liver, in case of urinary retention, heart defects.

Appointment during pregnancy and lactation

During pregnancy, Suprastin is not allowed in the first trimester and in the last month. As for the rest of the period, it is a relative contraindication. In this case, the treatment is carried out strictly on medical appointments and under the supervision of a specialist.
The active ingredient of the drug easily penetrates the placental barrier, its action may adversely affect the development of the unborn child during the laying of the main organs and systems. Chloropyramine easily penetrates into breast milk, so if during lactation it becomes necessary to use the drug, breastfeeding is temporarily stopped.

Dosage and method of use

As indicated in the instructions for use, Suprastin tablets are taken orally at the same time as a meal, not chewed and washed down with a sufficient amount of water.
Dosing regimen:
    children aged 3–6 years: ½ pc. (12.5 mg) 2 times a day;
    children aged 6–14 years: ½ pc. (12.5 mg) 2-3 times a day;
    children over 14 years old and adult patients: 1 pc. (25 mg) 3-4 times a day; daily dose is 75–100 mg.
If the patient has no side effects, the dose can be gradually increased, but the maximum daily dose should not exceed 2 mg / kg body weight.
The course of therapy depends on the symptoms of the disease, its duration and clinical course.

Side effect

Most often suprastin causes the development of side effects from the central nervous system and the digestive tract. Less common are disorders of the cardiovascular system and the blood-forming system. In most cases, side effects disappear 4 to 6 hours after discontinuation of the drug. For further treatment, you should contact your doctor to replace suprastin with a more suitable drug.
The following side effects of suprastin on the part of the central nervous system are distinguished: decreased concentration of attention;
    headache;
    euphoria;
    psychomotor agitation;
    convulsions;
    tremor (tremor);
    athetozopodobnye movement (twisting limbs);
    lack of coordination of movements;
    general weakness;
    drowsiness;
    depression;
    fever;
    anxiety;
    hallucinations and others.
There are the following side effects of suprastin with the gastrointestinal tract:
    dry mouth;
    diarrhea;
    constipation;
    nausea;
    vomiting;
    pain in the supra umbilical region of the abdomen;
    disturbance of appetite, etc.
On the part of the cardiovascular system and the blood-forming system, the following side effects are distinguished:
    the occurrence of arrhythmias;
    agranulocytosis (reduction in the number of neutrophils, eosinophils and basophils circulating in the blood);
    lower blood pressure;
    paradoxical increase in blood pressure;
    increase in heart rate;
    leukopenia (decrease in the number of leukocytes circulating in the blood).
Among other side effects, an increase in intraocular pressure is sometimes encountered, especially dangerous if a patient has angle-closure glaucoma. Such a condition may eventually lead to optic atrophy and irreversible blindness. Also, suprastin in rare cases may aggravate urinary retention in patients with prostate adenoma.

Overdose

In case of Suprastin overdose, serious adverse reactions can occur from the nervous system. In adults, there is a violation of motor coordination, anxiety, ataxia, fever. The period of short arousal ends with convulsions, post-convulsive depression or falling into a coma.
In children with an overdose, dilated pupils, agitated state, anxiety, facial flushing, urinary retention, signs of tachycardia are observed. In the absence of timely assistance, the child may fall into a coma. In such conditions, patients are given gastric lavage, sorbents are prescribed, symptomatic therapy is performed, or rehabilitation measures are carried out.

special instructions

Before starting treatment, read the special instructions:
    Taking the drug at night may increase the symptoms of reflux esophagitis.
    When combined with ototoxic drugs Suprastin may mask early signs of ototoxicity.
    Suprastin can enhance the effect of ethanol on the central nervous system, and therefore, while taking the drug Suprastin, alcohol should be avoided.
    Diseases of the liver and kidneys may require a change (decrease) in the dose of the drug, and therefore the patient must inform the doctor about his liver or kidney disease.
Prolonged use of antihistamines can lead to disorders of the hematopoietic system (leukopenia, agranulocytosis, thrombocytopenia, hemolytic anemia). If during prolonged use there is an unexplained increase in body temperature, laryngitis, pale skin, jaundice, ulceration in the mouth, hematomas, unusual and long-lasting bleeding, it is necessary to perform a blood test to determine the number of formed elements. If the results of the analysis indicate a change in the blood formula, the drug is discontinued.

Interaction with other drugs

When prescribing the drug, it is necessary to take into account the interaction with other drugs:
    The drug enhances the action of barbiturates, M-anticholinergics, opioid analgesics.
    MAO inhibitors can enhance and prolong the anticholinergic effect of chloropyramine.
    When combined with ototoxic drugs Suprastin may mask signs of ototoxicity.
    Antihistamines can distort the results of skin allergy tests, therefore, a few days before the planned test, the use of drugs in this group should be stopped.

Reviews

We offer you to read the reviews of people who used the drug Suprastin:
Catherine
    And I have allergic swelling. I bought different drugs, both cheap and expensive, suprastin helps best (in general, the only thing that helps). True, two pills at a time. And after taking it “cuts”, you need to sleep 30-40 minutes. But everything passes.
Veronica
    I can not say anything bad about this drug, because my daughters always prescribed suprastin for allergies and he helped in specific cases. Of course there was some drowsiness, but antiallergic drugs always almost cause it, this is normal. If you choose the right dosage and carefully handle the medicine, which means you are careful with your health, then there will be no global problems.
Maria
    I have been allergic since childhood, allergic to foods, and it is not always possible to understand that I ate one that caused the rash. Suprastin is no substitute for me. It quickly relieves the symptoms of allergies, a rash and itching in a couple of days. The only downside is that the pills are bitter. Well worth Suprastin not cheap.

Shelf life and storage conditions

Suprastin in the form of tablets or solution for injection should be stored in a dry place at a temperature of 15 to 25 degrees. Keep out of the reach of children. The shelf life of the drug is 5 years from the date of issue.

Terms of sell

You can buy Suprastin without a prescription.