Chloropyramine tabs 25mg #20

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Chloropyramine user manual

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Composition and release form

Chloropyramine is available in two forms: as a solution for intramuscular and intravenous administration, as well as tablets.
Solution for intravenous and intramuscular administration is a clear liquid with a barely noticeable greenish or yellowish tinge with a characteristic odor. In each of the ampoules with a solution contains the active substance, the mass of which is 20 mg. There are packs of five or ten ampoules.
The content of the active substance in tablets Chloropyramine - 25 mg each. In the package - 20 pieces of tablets.

What does chloropyramine help?

    allergic conjunctivitis and rhinitis;
    hay fever and pollinosis;
    angioedema;
    allergic dermatosis;
    serum sickness;
    allergic reactions to insect bites;
    allergy to drugs.

Instructions for use

For acute allergic and anaphylactic reactions, chloropyramine is first administered intravenously with a gradual transition to intramuscular injections. Treatment of the child should take place under the supervision of a specialist, there is the likelihood of hypersensitivity.
At the initial stage of therapy, the duration of which is individual, it is unacceptable to engage in activities that require a reaction and concentration, including auto control. For the entire period of taking the pills, you should forget about the existence of alcoholic beverages. According to the instructions, the dosage of the drug is as follows:
    Dose for adults: not more than 150 mg per day. Take the pill should be 3-4 times a day with meals. Solution injections are made intramuscularly and intravenously, with no more than 2 ml of a two percent solution being injected.
    Dose for children. Babies from 1 to 12 months old can be given no more than 6.25 mg, up to 6 years old - 8.33 mg, from 7 to 14 - 12.5 mg. Take 3 times a day. It is better for small children to give a tablet pounded to a powder.

Pharmacological effects

Chloropyramine is a blocker of H1 receptors. Chemical structure refers to ethylenediamine derivatives. Chloropyramine selectively inhibits histamine H1 receptors and reduces capillary permeability. Prevents the development and facilitates the course of allergic reactions.
It has a sedative and pronounced antipruritic effect. It has moderate peripheral anticholinergic and antispasmodic activity and antiemetic effect.

Contraindications

Numerous reviews of Chloropyramine warn about the presence of a number of contraindications in which the use of the drug is not highly recommended. Their list is presented below:
    exacerbation of gastric ulcer;
    acute attacks of bronchial asthma;
    a combination of taking the drug with MAO inhibitors;
    prostatic hyperplasia;
    pregnancy and lactation;
    children less than 1 month old;
    hypersensitivity to the drug components, in particular, to ethylenediamine derivatives (including chloropyramine).

Side effects of Chloropyramine

    drowsiness, incoordination of movements, dizziness, slowed down psychomotor reactions, decreased concentration of attention;
    dry mouth, throat, nose;
    nausea, diarrhea, loss of appetite or its increase, gastralgia;
    lowering blood pressure, arrhythmias and tachycardia.

Drug interactions

Analogs and the drug itself enhance the effectiveness of hypnotics, m-anticholinergics, local anesthetics, opioid analgesics, sedative drugs, tranquilizers and general anesthesia drugs.
MAO inhibitors and tricyclic antidepressants increase the inhibitory and m-holinoblokiruyuschee effect of chloropiramine on the central nervous system, and phenamine and caffeine, on the contrary, reduce it.
Treatment with the drug against the use of ethanol increases the risk of severe depression of the central nervous system.


Special conditions

It is forbidden to take the drug at the same time with alcohol. Due to the possibility of increasing the symptoms of reflux esophagitis, the drug is not recommended for use at bedtime.
Prolonged use of Chloropyramine can cause disorders of hematopoiesis, resulting in an unreasonable increase in temperature, pale skin, laryngitis, the appearance of hematomas, difficult to stop and unusual bleeding, ulcers on the oral mucosa. In the presence of these symptoms there is a need for immediate treatment to the doctor.
Analogs, like the drug itself, sometimes give a distorted picture in the case of allergy tests. To avoid this, the instructions for Chloropyramide recommends that you stop taking the drug a few days before the intended test.
The combined use of ototoxic drugs and Chloropyramine masks the manifestations of ototoxicity.
The use of the drug may adversely affect concentration. Therefore, at the time of drug therapy should refrain from activities that require this quality.

Terms of sell

You don't need a prescription to buy Chloropyramine.