Sorbifer Durules tabs #50

Instruction for Sorbifer Durules

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Sorbifer (international name - Iron Sulfate + Ascorbic Acid) belongs to the group of antianemic drugs that make up the lack of iron. The drug is highly effective and safe, due to which it is prescribed during pregnancy and breastfeeding.
In this article, we will consider why doctors prescribe Sorbifer durules, including instructions for use, analogues and prices of this drug in pharmacies. REAL REVIEWS of people who have already taken advantage of Sorbifer durules can be read in the comments.

Composition and form of release

The drug Sorbifer Durules is available in oral dosage form. They have a round shape, a biconvex surface, yellow color. The composition of the drug includes several main active ingredients.
    One tablet consists of: 320 mg of iron sulfate (including 100 mg of iron) and 60 mg of ascorbic acid.
    Excipients: hypromellose, titanium dioxide, magnesium stearate, carbomer 934P, yellow iron oxide, paraffin, polyethylene powder, macroscope 6000 and povidone.
Clinical and pharmacological group: antianemic drug.

What is Sorbifer durules used for?

Sorbifer Durules is used in the presence of iron deficiency anemia, when the amount obtained with iron products is too small, or there is a need for regular replenishment with prolonged bleeding. And also as preventive measures during pregnancy and lactation, with heavy menstruation and blood donors. Also, the drug is prescribed if there is a need for an increased amount of iron - for children and the elderly.

Pharmacodynamics and pharmacokinetics

The therapeutic properties of the drug are due to the presence of iron in its composition in combination with ascorbic acid. Iron, in itself, is an integral part of the human body, its important functional unit. It is part of hemoglobin, takes part in oxidative reactions in tissues. Ascorbic acid improves quality and affects the body's absorption of iron.
    Durules is a special technology for the preparation of the drug, which allows iron ions to be uniformly and gradually released in the intestine not under the influence of digestive juices, but as a result of peristalsis (wave-like movements of the intestinal walls). Such a gradual (over 6 hours) release of iron ions prevents the creation of an increased amount of them in the digestive organs and does not allow the irritating effect of iron ions on the mucosa of the digestive tract.
The absorption of the drug in the small intestine, thanks to this technology, is high, 30% higher than that of other iron preparations. It is ascorbic acid that increases its absorption.

Instructions for use

According to the instructions for use, I take Sorbifer durules inside. Coated tablets can not be divided or chewed. The tablet should be swallowed whole and drink no less than half a glass of liquid. The duration of therapy is determined individually depending on the concentration of iron in the blood plasma. The average duration of treatment is 3-6 months.
    The standard dose is 1 tablet 2 times / day (morning / evening) 30 minutes before meals. The tablet should be swallowed whole, washed down with water (200 ml). With the development of adverse reactions, the dose should be reduced by 50% (one tablet / day).
    During the first 6 months of pregnancy, the recommended dose is 1 tablet / day, in the last trimester of pregnancy, during lactation - 1 tablet 2 times / day.
After normalizing the level of hemoglobin, the administration of the drug Sorbifer Durules should be continued until the iron reserves are completely restored (about 2 months).

Overdose

If the dose of the pharmaceutical agent required for treatment is exceeded, severe pain in the epigastric zone is noted, blood pressure significantly decreases, a distinct heartbeat, low pulse, body temperature decreases, and sensitivity is impaired.
In severe overdose, clotting disorders, fever, severe liver and kidney disorders, convulsions and coma, which develop in the period of 6-12 hours, are noted.
Overdose therapy is carried out in a hospital. Assign gastric lavage. A raw egg and milk are used to bind iron ions in the stomach and intestines. Perform symptom therapy.

Contraindications

Do not use the drug in such cases:
    Children under 12 years of age (due to lack of clinical data).
    Violation of iron utilization (lead anemia, sideroblastic anemia, hemolytic anemia).
    Hypersensitivity to the components of the drug.
    Esophageal stenosis and / or obstructive changes in the digestive tract.
    Increased iron content in the body (hemosiderosis, hemochromatosis).
With caution: peptic ulcer of the stomach and duodenum, inflammatory bowel disease (enteritis, diverticulitis, ulcerative colitis, Crohn's disease).

Side effects

Against the background of taking Sorbifer Durules tablets, a number of pathological negative reactions from various organs and systems are possible:
    Allergic reactions - a rash on the skin, its itching, specific pathological changes in the form of swelling and a rash, resembling a nettle burn.
    Nervous system - dizziness, periodic headache.
    The digestive system - nausea, periodic vomiting, pain in the abdomen, impaired stool (constipation or diarrhea).
    Rarely, ulcerative lesions of the walls of the stomach, duodenum, as well as narrowing (stenosis) of the esophagus can develop.
    Other: rarely - general weakness, hyperthermia of the skin.
When taking an excessive dose of the drug are possible: vomiting, abdominal pain, diarrhea with an admixture of blood, pallor of the skin, weakness or fatigue, paresthesia, cold clammy sweat, hyperthermia, acidosis, decreased blood pressure, weak pulse, rapid heartbeat; in severe cases - hypoglycemia, coagulopathy, signs of peripheral circulatory collapse, hyperthermia, renal failure, liver damage, muscle cramps and coma may appear after 6-12 hours.

Reviews

Ulyana
In general, I was very far from all pharmaceuticals, and I didn’t drink any drugs, until I became pregnant. I also met Sorbifer during pregnancy, a therapist prescribed it to me, somewhere around 16 weeks hemoglobin in the analyzes turned out to be low - 104.
The drug fulfilled its main task, took it 1 tablet 2 times a day, a month later the hemoglobin was normal in the tests - 123, but the doctor said that the drug should be taken further for prophylaxis so that iron deficiency no longer occurs.
Nina
The drug was first prescribed by a hematologist 7 years ago, then I found out about my chronic iron deficiency anemia. Frequent dizziness, weakness, loss of consciousness, bad nails, hair falling out - with these symptoms I lived, not suspecting that the problem was hemoglobin. As soon as I begin to feel unwell, I drink “Sorbifer” for a month. For a month of application, my Hb rises by 10-15 units, which is palpable for me. The problem of replenishing iron during pregnancy and lactation was especially acute. From the second trimester I constantly drank “Sorbifer Durules”. After childbirth, hemoglobin in the blood was 88, with the help of the drug it was possible to level the figure.

Terms of sell

You can buy Sorbifer Durules without a prescription.