Magnelis B6 Forte user manual
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Magnesium is a vital element that is necessary for the normal functioning of cells, is involved in most metabolic reactions. Participates in the regulation of the transmission of nerve impulses and in the contraction of muscles.
The body gets magnesium with food. Lack of magnesium in the body can be observed in violation of the diet (diet) or with an increase in the need for magnesium.
Pyridoxine (vitamin B6) is involved in many metabolic processes, improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.
A serum magnesium content between 12 and 17 mg / l (1-1.4 mEq / l or 0.5-0.7 mmol / l) indicates moderate magnesium deficiency; below 12 mg / l (1 mEq / l or 0.5 mmol / l) - indicates a severe magnesium deficiency.
Magnelis B6 forte and Magnelis B6 - what's the difference?
Both drugs perform one function - they normalize the amount of magnesium in the body. But between them there is a significant difference - the dosage.
The tablet of Magnelis B6 Forte has a double dosage of active ingredients - it can replace 2 tablets of Magnelis B6.
A slight change affected the composition. In the Forte version of the drug, magnesium lactate was replaced with magnesium citrate. It implies a magnesium salt of citric acid, and is used as an osmotic laxative.
Indications for use
What helps Magnelis B6 forte? According to the instructions, the drug is prescribed with an established magnesium deficiency, isolated or associated with other deficient conditions, accompanied by the following symptoms:
irritability,
minor sleep disturbances
gastrointestinal cramps,
cardiopalmus,
increased fatigue
muscle aches and cramps
tingling sensation in muscles.
Instructions for use Magnelis B6 forte, dosage
Tablets should be taken with food entirely, without chewing and drinking fresh water.
Standard dosages of Magnelis B6 forte according to the instructions for use:
Adults - from 3 to 4 tablets per day, divided into 2-3 doses.
Children over 6 years old (weighing about 20 kg) - dosage 10-30 mg / kg / day (0.4-1.2 mmol / kg / day), i.e. 2-4 tablets per day, divided into 2- 3 doses, with meals.
The course duration is 30 days, if the symptoms do not disappear, the further use of the drug is impractical.
Side effects
The instruction warns about the possibility of the development of the following side effects when Magnelis B6 is appointed forte:
On the part of the immune system: very rarely (<0.01%) - allergic reactions, including skin reactions.
On the part of the gastrointestinal tract: the frequency is unknown (according to the available data it is not possible to estimate the frequency of occurrence) - diarrhea, abdominal pain, nausea, vomiting, flatulence.
Contraindications
It is contraindicated to appoint Magnelis B6 forte in the following cases:
hypersensitivity to any of the components of the drug;
severe renal insufficiency (CC <30 ml / min);
phenylketonuria;
age up to 12 years (efficacy and safety not established);
hereditary galactosemia, malabsorption of glucose and galactose, or lactase deficiency (due to the presence of lactose in the formulation); about
simultaneous reception of levodopa.
Carefully:
moderate renal failure (risk of hypermagneemia).
Use during pregnancy only if necessary, on the recommendation of a doctor.
The simultaneous use of drugs containing phosphates or calcium salts, may worsen the absorption of magnesium in the intestine.
When prescribing inside tetracyclines, it is necessary to observe an interval of not less than 3 hours between ingestion of tetracycline and Magnelis B6 forte, since magnesium preparations reduce the absorption of tetracyclines.
Overdose
In normal kidney function, an overdose of magnesium when administered orally does not usually lead to toxic reactions. However, in the case of kidney failure, the development of magnesium poisoning is possible. The severity of symptoms depends on the concentration of magnesium in the blood.
Overdose symptoms include a decrease in blood pressure, nausea, vomiting, CNS depression, decreased reflexes, ECG changes, respiratory depression, coma, cardiac arrest, and respiratory paralysis, anuric syndrome.
Recommended rehydration and forced diuresis. In renal insufficiency, hemodialysis or peritoneal dialysis is necessary.
special instructions
Designed for adults and children over 12 years old.
Magnelis B6 forte contains lactose monohydrate, so its use is not recommended for patients with hereditary galactosemia, glucose malabsorption and galactose syndrome, or lactase deficiency.
In moderate renal insufficiency, the drug should be taken with caution because of the risk of developing hyairmagnies.
If calcium and magnesium are deficient at the same time, magnesium deficiency should be replenished before starting calcium supplements or calcium-containing dietary supplements.
When using pyridoxine in high doses (more than 200 mg per day) for a long time (for several months or in some cases - years), sensory axonal neuropathy may develop, which is accompanied by symptoms such as numbness and impaired proprioceptive sensitivity, distal tremor limbs and gradually developing sensory ataxia (impaired coordination of movements).
These disorders are usually reversible and disappear after stopping the drug.
Storage conditions
Store at temperatures up to 25 degrees in a dry, dark place out of reach of children. Shelf life - 2 years.
Terms of sell
You can buy Magnelis B6 Forte without a prescription.