Hepatrombin cream 500me + 3mg + 4mg/gr 40gr

Hepatrombin cream instruction for use

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pharmachologic effect

The drug is an external drug used to treat vein diseases. The drug contains high therapeutic dosages of heparin, a direct acting anticoagulant.
Heparin has a local anti-edema, antithrombotic and anti-inflammatory effects, makes local blood flow better, stimulates regenerative processes. Heparin also improves the processes of granulation and epithelization of the skin and normalizes tissue trophism.
With local use, systemic absorption of heparin is negligible. The active ingredient of the drug normally penetrates the skin and accumulates in the upper layers of the skin.
Heparin is removed from the tissues slowly, the half-life reaches 1 hour.

Indications for use

The drug is used in the treatment and prevention regimens of phlebitis, thrombophlebitis, thrombosis and varicose veins (including in the schemes of postoperative therapy).
Hepatrombin cream is prescribed to patients with trophic lesions of the lower leg, which are associated with impaired local blood flow, including in patients with diabetes.
The drug may be prescribed for injuries (including sports), bursitis, tendovaginitis, mastitis, carbunculosis, furunculosis and lymphangitis.
Hepatrombin cream can be used to prevent the occurrence of postoperative scars.

Mode of application

Hepatrombin cream is used externally. In the treatment of acute pathological processes, the drug 50,000 IU is prescribed, Hepatrombin 30,000 IU is used as a maintenance therapy and for prevention.
The duration of therapy and dosage of heparin is determined by the doctor.
It is often prescribed to apply a cream with a thickness of 1 mm on the affected skin and adjacent skin. The cream is suggested to be used up to 3 times per day and gently rub it in when applied.
For diseases of the veins, the drug is suggested to be used in conjunction with a venous bandage.
For ulcers, hepatrombin cream should be applied around a trophic ulcer.
For phlebitis, rubbing cream into the skin is not appropriate; in such cases, Hepatrombin cream is applied with a layer thickness of 1-2 mm and bandages the affected area with an elastic bandage.
On furuncles and carbuncles, it is suggested to apply a gauze bandage with Hepatrombin cream up to 2 times a day.
The duration of therapy is individual.
It is necessary to avoid getting Hepatrombin cream in the eyes, otherwise it is necessary to wash the eyes with plenty of running clean water.

Side effects

The drug is generally well tolerated by patients. In some cases, when using the drug, the patients had a slight development of skin irritation and hyperemia, which took place independently.
In patients with hypersensitivity, allergic reactions are likely to occur when using Hepatrombin cream. For example, it is forbidden to exclude the risk of urticaria, burning, flushing, itching, skin rash, angioedema and hemorrhages.
In some cases, with the external use of Hepatrombin cream, patients developed a vesicular and pustular rash.
When using Hepatrombin Cream on large areas of the skin in patients there is a risk of developing systemic side effects of heparin.
In case of accidental oral administration of the cream, the development of vomiting is noted.

Contraindications

Hepatrombin cream is not used in the treatment of patients with personal intolerance to heparin and auxiliary components of the cream.
Hepatrombin cream should not be prescribed to patients with trophic bleeding leg ulcers and infected open wounds.
Hepatrombin cream is contraindicated in patients with bleeding disorders, including thrombocytopenia, hemophilia, hemorrhagic diathesis, purpura, and a tendency to develop bleeding.
You can not apply the cream Hepatrombin on moist wounds, mucous membranes and periorbital area.
Hepatrombin cream is not used in pediatrics.

Pregnancy

During breastfeeding and pregnancy, Hepatrombin cream can only be used as directed by the doctor and in cases where the possible benefits outweigh the potential risks to the child.

Interaction with other drugs

Hepatrombin cream is not used in conjunction with other external agents in one area of ​​the skin.
It is necessary to avoid the simultaneous administration of the cream Hepatrombin with topical medications containing tetracycline, salicylic acid, hydrocortisone and anticoagulants.

Overdose

Given the slight absorption of heparin in the local use, the risk of overdose when using cream Hepatrombin is negligible.
In case of accidental ingestion of cream inside, the development of vomiting is likely, in which case it is necessary to carry out a gastric lavage and, if indicated, to prescribe symptomatic therapy.

Release form

Cream Hepatrombin 40 g in tubes, in a pack of laminated cardboard - 1 tube.

Storage conditions

Cream Hepatrombin should be stored in places inaccessible to children, while maintaining a temperature of 15 to 25 degrees Celsius.
Shelf life - 3 years.

Composition

100 g of Hepatrombin 30000 cream contain:
Sodium Heparin - 30,000 IU;
Excipients, including dexpanthenol.
100 g of Hepatrombin 50,000 cream contain:
Sodium heparin - 50,000 IU;
Excipients, including dexpanthenol.

Terms of sell

You can buy Hepatrombin cream without a prescription.