Salbutamol aerosol 100mcg/dose 200doses

Salbutamol belongs to the group of drugs of synthetic origin. According to the clinical and pharmacological action, it is classified as an anti-inflammatory group, beta2-adrenergic agonists and mucolytics with bronchodilator effect.
The drug is used to eliminate and prevent suffocating attacks in bronchial asthma. Refers to medications for emergency medical care.
The drug is in the form of an aerosol for inhalation. Salbutamol in the form of an aerosol is a white or almost white suspension, which is under pressure in an aluminum cylinder with a metering valve, equipped with an inhaler nozzle with a protective cap; the drug is sprayed in the form of an aerosol jet when exiting the container.
The can is packed in a cardboard box, which also contains instructions for use.
The medicine is released only on prescription by the attending physician. Salbutamol for inhalation must be stored in a place protected from sunlight at a temperature not exceeding 30 degrees. Shelf life is 2 years.

Composition and pharmacological action of salbutamol

Salbutamol is used as an active compound in the composition of the drug. In addition to the main component, additional substances are present in the preparation.
Auxiliary compounds are:
    Cetyl oleate;
    Fluorotrichloromethane;
    difluorodichloromethane.
Salbutamol is a selective beta2-adrenergic receptor agonist. In therapeutic doses, the drug acts on beta2-adrenergic receptors of the smooth muscles of the bronchi. It may also have a minor effect on beta1-adrenergic receptors of the heart muscle.
The active compound of Salbutamol in accordance with the instructions for use has a pronounced bronchodilating effect. The use of the drug can prevent and stop the development of bronchospasm and reduce resistance in the airways, and the drug also makes it possible to increase the vital capacity of the lungs.
If the use of salbutamol aerosol is carried out in accordance with the recommendations of the instructions for use, then the medication does not adversely affect the cardiovascular system. Under the influence of Salbutamol, the coronary arteries are able to expand.
A drug can exhibit metabolic effects such as lipolytic and hyperglycemic. The medication can affect the synthesis of insulin and glycogenolysis, under the influence of the drug, a decrease in the plasma content of potassium can be observed.
Salbutamol begins to act within 5 minutes after inhalation, the maximum effect is achieved after 30–90 minutes, and its duration is from 4 to 6 hours.
After inhalation of the drug, approximately 10–20% of the dose taken reaches the lower respiratory tract. The remaining amount of the drug remains in the inhaler or enters the surface of the mucous membrane of the oropharynx and is swallowed. The part of the drug that settles on the mucous membrane of the respiratory tract enters the blood and lung tissues, but in them it is not metabolized.
Salbutamol is approximately 10% bound to plasma proteins. Its metabolism occurs in the liver, and the drug is excreted mainly with urine in the form of phenolic sulfate and unchanged.
The elimination half-life makes 4-6 hours. Salbutamol conjugate and unchanged salbutamol are excreted mainly in the urine. An insignificant part of the drug (about 4%) is excreted with bile, and some more - with feces.

Pros

    The drug is highly effective.
    Using a medication allows you to get a quick therapeutic result.
    It has one of the lowest prices among similar products.
    It does not affect the speed of psychomotor reactions, which allows the patient not to limit himself in activity

Cons

    Prescription drug
    The medication is prohibited for use during pregnancy and breastfeeding.
    The presence of side effects that are rare, but can develop during therapy
    Some manufacturers have inconvenient inhaler designs
    Forbidden to use in patients of children under 2 years of age.

Instructions for use of the drug

The drug should be used strictly as prescribed by the attending physician in accordance with its recommendations and the requirements of the instructions for use.

Indications for use

Salbutamol in the form of an aerosol is recommended for use for relief and prevention of bronchospasm.
The main indications are:
    the presence of chronic bronchitis;
    chronic obstructive pulmonary disease;
    emphysema.
The drug has established itself well as a remedy for the relief of attacks of bronchial asthma, including in severe cases of pathology. The drug can be used to prevent attacks of bronchospasm that occurs as a result of exposure to allergens or provoked by increased physical exertion.
The medication can be used both for monotherapy and as part of complex therapy during maintenance treatment for bronchial asthma.

Method of use

Aerosol for inhalation Salbutamol is intended for inhalation use. The use of aerosol requires compliance with certain recommendations.
The recommendations are as follows:
    Before each procedure, shake the bottle thoroughly, put on a spray bottle on it, and remove the cap from the spray bottle.
    The cylinder is turned upside down, a deep exhalation is made, the mouthpiece is clasped by the lips and, with a strong inspiration, the bottom of the cylinder is pressed.
    After a strong injection of the drug, you should hold your breath for several seconds.
    The mouthpiece is pulled out of the mouth and a slow exhale is made.
After each use of the drug, the mouthpiece must be closed with a lid. For young children and patients who are not able to correctly perform a breathing maneuver, you can use a spacer that smoothes out the inaccuracies of asynchronous inspiration and increases tidal volume.
Recommended dosages are:
    relief of asthma attacks - 1-2 doses, and in the absence of a sufficient therapeutic effect, the procedure can be repeated after 5 minutes, reuse is allowed only after 120 minutes;
    mild to moderate asthma - 1-2 doses up to 4 times a day, it is additionally recommended to use anti-asthma drugs;
    for the prevention of physical effort asthma, use 1-2 doses 20-30 minutes before exerting physical activity on the body.
For the prevention of bronchial asthma attacks and treatment of attacks in children aged 2 to 12 years, it is recommended to use 1-2 doses. The maximum allowable dosage is 12 inhalations per day - 1.2 mg.

Contraindications

When using the drug, the possible presence of contraindications to the use of salbutamol in the patient should be considered.
Such contraindications are:
    Cardiac ischemia.
    Heart rhythm disturbances.
    Myocarditis.
    Aortic stenosis.
    Heart defects.
    Severe heart failure.
    Uncompensated diabetes.
    Epileptic seizures.
    Glaucoma.
    Renal and liver failure.
    Pyloroduodenal narrowing.
    Period of pregnancy.
    The simultaneous use of non-selective β-blockers, including propranolol.
    The patient's age is up to two years.
    The presence of hypersensitivity to the components of the drug.
Caution is required when prescribing the drug during breastfeeding, in the presence of hyperthyroidism and arterial hypertension.

Side effects

In the process of conducting therapy and prophylaxis with the use of Salbutamol, the patient may develop side effects and undesirable reactions from various organs and their systems.
The most common are:
    cough;
    nasal congestion, urticaria, erythema, bronchospasm, angioedema and other hypersensitivity reactions;
    hypokalemia, reversible metabolic disorders;
    increased blood pressure, a slight increase in heart rate, arterial hypotension, arrhythmia, collapse, hyperemia of the skin of the face;
    headache, tremor, dizziness, sleep disturbance, fatigue, irritability, insomnia, anxiety;
    muscle cramps;
    violation of taste sensations, nausea, vomiting, irritation or dryness of the oral mucosa, pharyngitis.
If these signs appear, you should contact your doctor for advice and adjustments to drug therapy.
In case of an overdose of Salbutamol, the patient may experience nausea, urge to vomit, decreased blood pressure, muscle tremor, tachycardia, headache, agitation, lack of oxygen in the blood, hyperglycemia, tachyarrhythmia, peripheral vasodilation, convulsions, hallucinations.
    The best antidote is cardioselective beta-blockers, but they should be used carefully, since there is a risk of bronchospasm.

Drug Interactions and Special Instructions

The simultaneous administration of Salbutamol with drugs whose action is aimed at treating angina pectoris leads to a possible mutual suppression. Such drugs are non-cardioselective beta-blockers.
The use of salbutamol in combination with theophylline increases the likelihood of arrhythmias and tachycardia. Complex administration with diuretics and glucocorticosteroids can provoke a decrease in the amount of potassium in the blood plasma.
Tricyclic antidepressants, monoamine oxidase inhibitors - enhance the action of Salbutamol and a sharp decrease in blood pressure. Combination with anticholinergics can increase intraocular pressure. The use of drugs containing thyroid hormones with the simultaneous use of salbutamol provokes an increase in side effects on the heart.
Salbutamol enhances the action of drugs that stimulate the central nervous system. The use of the drug also increases the risk of glycoside intoxication.
Given the ability of the drug to exert an exciting effect on the sympathetic nervous system, patients with diseases of the cardiovascular system, with epilepsy, glaucoma and hyperthyroidism should use Salbutamol with caution. If the use of the recommended therapeutic dose gives a negative result and does not bring proper relief, or the duration of the therapeutic effect is less than three hours, you should consult your doctor.
Salbutamol is contraindicated in children under two years of age. During pregnancy and lactation, Salbutamol is used with caution and only if the expected benefit to the mother outweighs the possible risk to the fetus or child.
    The use of the drug does not affect the speed of psychomotor reactions, therefore, there are no restrictions on driving vehicles, as well as complex and potentially life-threatening mechanisms.

Reviews

Most patients report salbutamol as an effective drug. For a large number of patients suffering from bronchial asthma, the use of this drug is a real salvation. Using the medication can quickly improve the patient's condition, even in the event of severe bronchospasm.
In their reviews, patients indicate that the drug quickly helps with asthma attacks, as well as when treating obstructive bronchitis. Most often, the relief of the condition gives the use of a single therapeutic dose.
The advantage of the drug, many users call it a low cost compared to most imported analogues. Patients indicate the convenience of using an inhaler.
Also, a rare development of side effects is indicated in the reviews as a merit of the drug.

Terms of sell

You don't need a prescription to buy Salbutamol.