Voltaren injections 25mg/ml 3ml #5

Instruction for Voltaren injections

You can buy Voltaren injections here

The active ingredient - Diclofenac - has anti-inflammatory, antipyretic and analgesic effects, which are due to the ability to reduce the synthesis of prostaglandins, which are mediators of inflammation, pain and fever.
A decrease in the number of prostaglandins in the outbreak, inflammation causes the analgesic effect of the drug, and a decrease in prostaglandins in the hypothalamus causes an antipyretic effect.
Voltaren injections in the treatment of primary dysmenorrhea not only eliminates pain, but also significantly reduces blood loss.
After intramuscular injection of 75 mg of diclofenac sodium, it begins to be absorbed immediately. The average value of its maximum plasma concentration is about 2.5 μg / ml (8 μmol / l) and is reached in approximately 20 minutes. With intravenous administration, therapeutic blood concentrations are reached immediately. There is a linear dependence of the amount of the absorbed active component on the dosage of the Voltaren prick.

Indications for use

What helps Voltaren injections? According to the instructions, the drug is prescribed in the following cases:
    ankylosing spondylitis;
    osteoarthritis;
    spondyloarthritis;
    spinal pain;
    diseases of extra-articular soft tissue of rheumatic nature;
    pain syndrome, as well as swelling and inflammation of soft tissues and joints, resulting from injuries;
    primary dysmenorrhea and other gynecological diseases that are accompanied by inflammation and / or pain.
The solution for intramuscular or intravenous injection can also be used for any kind of pain that is a result of the inflammatory process.
The drug has only an anesthetic effect, it does not affect the progression of the disease.

Instructions for use injections Voltaren

Solution for injection is intended for intramuscular and intravenous administration. The injection is often done intramuscularly, after the appointment of a doctor. Intravenous administration is allowed in case of severe pain intensity.
It is not recommended to use injections for more than 2 days in a row. A long course of treatment is not recommended, since it increases the risk of side effects. The maximum duration of the drug is 5 days.
If necessary, Voltaren injections can be combined with other medicinal forms of the drug, but it is not recommended to exceed the daily dose of 150 mg.
The drug is injected deep into the muscle, into the upper outer buttock square. The standard dosage of Voltaren injections according to the instructions is 75 mg (1 ampoule) once a day.
With attacks of migraine, 75 mg (1 ampoule) is prescribed. The best effect is achieved if Voltaren is given an injection as early as possible after the onset of an attack. If required, suppositories should be used on the same day at a dose of up to 100 mg. The total daily dosage should not exceed 175 mg.
In the case of a severe pain syndrome, you can assign 2 shots with an interval of several hours, in which case a second injection is made into the opposite buttock.

Side effects

The instruction warns about the possibility of the development of the following side effects when prescribing injections Voltaren stabs:
    The digestive system - nausea, vomiting, abdominal pain, bloating (flatulence), loss of appetite up to anorexia (no desire to take food), stomatitis (inflammation of the oral mucosa), intestinal membrane strictures. Sometimes pancreatitis (inflammation of the pancreas) can develop. In rare cases, gastritis (inflammation of the gastric mucosa) and gastrointestinal bleeding may develop.
    Liver and biliary tract - increase in blood levels of liver enzymes (AST, ALT), which indicates damage to hepatocytes, drug toxic hepatitis, a violation of bile excretion with the development of cholestatic jaundice.
    Nervous system - depression (pronounced and prolonged decrease in mood), disorientation in time and space, sleep disturbances, headache, tinnitus, aseptic meningitis (non-infectious inflammation of the meninges), confusion, hallucinations, impaired skin sensitivity. Less likely to develop seizures
    Eyes - blurred vision, diplopia (double vision), optic neuritis.
    Cardiovascular system - palpitations, tachycardia (increased heart rate), development of heart failure, vasculitis (vascular inflammation), reduction in systemic arterial pressure (hypotension).
    Respiratory - asthma (spasm of the bronchi with their constriction and impaired passage of air), pneumonitis (inflammation of the alveoli of the lungs).
    Skin and subcutaneous tissue - Stevens-Johnson syndrome (the appearance of multiple blisters on the skin filled with fluid), toxic epidermal necrolysis, erythema (redness of the skin), alopecia (hair loss).
    Urogenital system - acute renal failure, interstitial nephritis (inflammation of the kidneys), papillary necrosis (cell death of the papillae of the kidneys), in men very rarely can develop impotence.
    The blood system and the red bone marrow are thrombocytopenia (a decrease in the number of platelets in the blood), leukopenia (decrease in leukocytes) and anemia (anemia).
    Allergic reactions - a rash on the skin, itching and hives often develop (a characteristic rash and swelling of the skin resembling a stinging nettle). Less commonly, a severe allergic reaction in the form of angioedema of the Quincke (pronounced swelling of the skin and subcutaneous tissue in the face or genital organs) or anaphylactic shock (severe general condition with a critical reduction in systemic blood pressure and multiple organ failure) develops less frequently.
    Reactions in the area of ​​the injection in the form of infiltration (compaction of the skin or subcutaneous tissue), redness and pain. In case of infection of the injection site, the development of a subcutaneous abscess (the formation of a confined cavity filled with pus) is possible.

Contraindications

It is contraindicated to appoint Voltaren injections in the following cases:
    Peptic ulcer and duodenal ulcer in the acute phase (internal bleeding, perforation);
    Crohn's disease, ulcerative colitis and other inflammatory inflammatory bowel disease in the acute phase;
    Severe renal, hepatic, heart failure;
    Active liver disease;
    Coronary artery bypass surgery;
    Hyperkalemia (diagnosed);
    Gestation period;
    Children and adolescents up to 18 years;
    Conditions involving the risk of bleeding.
Caution should be given to patients with bronchial asthma, cardiovascular diseases or high risk of their development, seasonal allergic rhinitis, chronic infectious pathologies of the respiratory system, swelling of the nasal mucosa (including polyps), diabetes mellitus, arterial hypertension, dyslipidemia or hyperlipidemia, impaired hemostasis, alcohol and / or tobacco addiction.
With extreme caution used in the treatment of elderly patients.

Overdose

Overdose symptoms are tinnitus, dizziness, seizures, gastrointestinal bleeding, vomiting. When used in very high doses, severe liver damage and the development of acute renal failure may occur.
Conducted general detoxification and symptomatic therapy.

What do the reviews say?

People who used the drug, leave positive reviews about Voltaren injections - there is a rather strong and prolonged anti-inflammatory and analgesic effect of the injection and tablet form of the drug, as well as the rare occurrence of negative side effects, compared with similar drugs of domestic production.

special instructions

Before starting a course of treatment with Voltaren injection solution, it is first necessary to test for sensitivity and the presence of allergies, which is the first dose of the minimum dose.
It is not recommended to administer the drug for anesthesia without determining the cause of the inflammatory process, as this may lead to masking of the symptoms and impede the diagnosis of pathology.
During drug treatment, it is necessary to monitor the condition of the digestive system, in case of the first symptoms indicating possible bleeding, the use of injection solution must be stopped.
In the case of a concomitant pathology of the gastrointestinal tract, the question of the necessary parallel use of drugs that reduce the acidity of the gastric juice and enveloping its mucous membrane is solved.
It is desirable during treatment with the Voltaren injection solution to conduct periodic laboratory monitoring of the functional activity of the liver, kidneys and blood system.
In the first and second trimester of pregnancy, prescribing is possible only if the expected benefit to the mother outweighs the potential risk to the fetus. The use of solution for injection Voltaren in the third trimester of pregnancy and during breastfeeding is not recommended.

Drug interactions

Simultaneous use of the drug with inhibitors of CYP2C9 increases the concentration of diclofenac in the blood.
Voltaren injections can increase the content of digoxin and lithium in the blood plasma.
The drug reduces the effect of antihypertensives and diuretics.
The combination of diclofenac with anticoagulants, antiplatelet agents, serotonin reuptake inhibitors increases the risk of bleeding in patients.
Simultaneous use with other non-steroidal anti-inflammatory drugs (NSAIDs) increases the risk of side effects.
Voltaren injections is recommended to be taken with caution no later than 24 hours before and not earlier than 24 hours after taking methotrexate.
Combined use with hypoglycemic agents is allowed with regular monitoring of glucose concentration in the blood.
Simultaneous intake with potassium-sparing diuretics may cause an increase in the level of potassium in the blood.
It is not recommended to use the drug with quinolone derivatives.
Voltaren injections increases cyclosporine nephrotoxicity and systemic exposure to phenytoin.

Terms of sell

You don't need a prescription to buy Voltaren injections.