Tempalgin user manual
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Given the variety of pathogenetic mechanisms of development of headaches, when stopping them use a wide Arsenal of drugs, including drugs, NSAIDs, psychotropic drugs, drugs that improve the blood supply to the nervous tissue.
The duration of continuous daily intake of the drug is limited to five days. If you need to increase the duration of the drug course, you should consult a doctor.
Composition and release form
Tempalgin is available in the form of coated tablets: biconvex, round, green (10 pieces in blisters, in a cardboard bundle of 2 or 10 blisters).
Ingredients 1 tablet:
active ingredients: metamizole sodium - 500 mg and tempidone (triacetonamine 4-toluenesulfonate) - 20 mg;
auxiliary components: MCC (microcrystalline cellulose), crospovidone (Povidone K25), talc, wheat starch, magnesium stearate;
film cover: Opadry II green 85 F 21526 (talc, macrogol 3350, partially hydrolyzed polyvinyl alcohol, quinoline yellow (E104) aluminum varnish, diamond blue (E133) FCF aluminum varnish, titanium dioxide (E171).
Tempalgin tablets are a clinico-pharmacological group of combined medicinal products with a pronounced analgesic and anti-inflammatory effect. The active components of the drug - metamizole and tempidone in the complex allow you to quickly cope with pain, reduce fever, eliminate inflammation.
The mechanism of action of the drug due to its composition. Metamizone belongs to analgesics, inhibits the synthesis of prostaglandins, which take part in the inflammatory response. Also, this tool inhibits the formation of pyrogens, normalizes cell membranes. The tempidone in the composition of the tablets affects the central cholinergic receptors, relieves tension, a sense of fear, negative emotions. The presence of this component in the composition of the drug enhances the effect of the analgesic, thereby ensuring a high effect after taking the medicine.
After taking the Tempalgin tablet, the active components are rapidly absorbed by the gastrointestinal tract, penetrate the blood flow, and are evenly distributed in the tissues, affecting the inflammatory process and pain syndrome. The drug is metabolized in the liver, excreted in the urine.
Indications for use
The use of Tempalgin tablets is indicated for pathological conditions in which it is necessary to achieve the therapeutic effects of this drug:
Pain in patients with increased excitability of the nervous system (migraine, pain during menstruation, toothache, headache, neuritis, neuralgia, pain in the joints and muscles, pain in injuries, wounds, burns, etc.);
Renal, hepatic or intestinal colic (in combination with antispasmodic agents);
Anesthesia before dental procedures;
Pain in the postoperative period;
Pain after invasive diagnostic procedures;
Increased body temperature in viral and infectious-inflammatory diseases.
children's age up to 14 years;
chronic heart failure;
severe renal and / or liver failure;
inhibition of hemopoiesis (leukopenia, granulocytopenia, infectious or cytostatic neutropenia, agranulocytosis);
aspirin bronchial asthma;
low blood pressure (systolic pressure less than 100 mm Hg. Art.);
deficiency of the enzyme glucose-6-phosphate dehydrogenase;
hypersensitivity to metamizole sodium, tempidone, auxiliary components of the drug or other derivatives of pyrazolone.
Relative (Tempalgin used with caution):
kidney disease (glomerulonephritis, pyelonephritis, including a history);
predisposition to arterial hypotension;
moderate renal and / or liver failure;
prolonged alcohol abuse.
Appointment during pregnancy and lactation
Tempalgin during pregnancy prescribed with caution. During the I and III trimester, the drug is contraindicated, because The tranquilizing component (triacetomine), which is part of it, can easily penetrate through the placental barrier into the blood and fetal brain. This substance can cause irreparable harm to the brain of the future baby.
It is not recommended to take Tempalgin and for the treatment of pain in nursing mothers.
Dosage and method of use
As indicated in the instructions for use Tempalgin tablets are taken orally, without chewing, with a sufficient amount of liquid, during or after a meal.
Adults appoint 1 tab. 1-3 times / day, with insufficient efficiency, you can take another 1 tab. The maximum single dose is 2 tab., The maximum daily - 6 tab. Reception duration - no more than 5 days.
Increasing the daily dose or increasing the duration of treatment is possible only under medical supervision.
Adverse reactions of the body after taking the drug are extremely rare, but in single cases the following symptoms may occur:
discomfort, abdominal pain;
heart rhythm disorder;
decrease in blood pressure;
cyanosis of the skin.
The appearance of such symptoms is the reason for the abolition of the drug. Many doctors claim that the risk of side effects increases, if in the process of taking the medicine a person does not comply with the permissible doses or takes pills with a history of contraindications.
With an overdose, the likelihood of side effects increases dramatically. Additionally, nausea and vomiting, ataxia and impaired consciousness, respiratory muscle paralysis and hemorrhagic syndrome may occur. The treatment uses gastric lavage, the use of laxatives and activated charcoal, symptomatic therapy is required.
Before you start using the drug, read the specific instructions:
Alcohol should not be taken while taking the drug.
Use of the drug in patients receiving cytostatics should be carried out only under medical supervision.
With prolonged (more than 7 days) taking the drug, it is necessary to control the blood picture and the functional state of the liver.
Tempalgin should not be used to relieve acute abdominal pain (until the cause is clarified).
Radiocontrast drugs, colloid blood substitutes and penicillin should not be prescribed with Metamizole sodium.
With the use of metamizole sodium, the development of agranulocytosis is possible, and therefore the detection of an unclear genesis of fever, chills, sore throat, difficulty swallowing, stomatitis, as well as the development of symptoms of vaginitis or proctitis is necessary to cancel the drug.
In connection with the anxiolytic effect of the drug during the period of taking Tempalgin, one should refrain from practicing potentially hazardous activities that require increased attention and quickness of psychomotor reactions.
Interaction with other drugs
When using the drug, you must consider the interaction with other drugs:
Tempalgin enhances the effects of ethanol.
Sedatives and tranquilizers enhance the analgesic effect of the drug.
With simultaneous use of tiamazol and cytostatics increase the risk of leukopenia.
With simultaneous use of metamizole sodium with cyclosporine, the concentration of the latter in plasma is reduced.
The simultaneous use of Tempalgin with chlorpromazine or other phenothiazine derivatives may lead to the development of severe hyperthermia.
With the simultaneous use of barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the action of metamizole sodium.
The simultaneous use of metamizole sodium with other non-opioid analgesics, tricyclic antidepressants, oral contraceptives, allopurinol can lead to mutual enhancement of toxic effects.
Metamizole sodium, displacing oral hypoglycemic drugs, indirect anticoagulants, GCS and indomethacin from the connection with protein, increases their effect.
Codeine, histamine H2 receptor blockers and propranolol slow down the excretion of metamizole and strengthen its action.
We offer you to read the reviews of people who used Tempalgin tablets:
I took uncontrollably tempalgin, with headaches, with menstrual pains. Approximately 10-20 tablets per month. In the end, I developed thrombocytopenia. The level of platelets in the blood dropped to 30 at a rate of 150-450. Bruises began to appear on the body. First, we looked for the cause, gave all kinds of blood tests for viruses (hiv, hepatitis), a full examination of the body. In the end, you just need to eat less pills. Although they helped well.
Tempalgin should not be used for those who are allergic to analgin. I trusted the pharmacist, who said that there was no analgin with the composition of the drug, although I doubted. Has accepted and there was an allergy, as well as on analginum. Observed symptoms of allergy: severe itching starting from the palms, then all over the body, redness, temperature.
Pretty budget, as for me, anesthetic drug. And most importantly, very effective. I apply mainly during the period of critical days - one pill for 12 hours is enough. When there are severe cramps on these days, I can take a few pills within an hour and everything goes away. Side effects with this application did not notice. Once again, a bad tooth ache. Saw tempalgin paired with potent drugs in order to reduce the load on the body from these drugs. And, too, did not notice any side effects from such use, but only received quick help.
Store the drug should be in a dry place at a temperature not higher than 25 ° C. Shelf life - 4 years.
Terms of sell
You don't need a prescription to buy Tempalgin.