Ketonal Duo caps 150mg #30

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Ketonal Duo instruction

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Every day, millions of people suffer from headache, dental, joint or other pain. Of course, to get rid of it, you must first consult a doctor and identify the cause of this unpleasant symptom. But it is not always possible to quickly get an appointment with the necessary specialist. Often people have to endure pain for several days, and sometimes more, which is sometimes quite difficult. Therefore, patients take painkillers. In the pharmaceutical market, you can see dozens of different medicines, but how to choose the right one?
Quite popular is the nonsteroidal anti-inflammatory drug "Ketonal DUO". Instructions for use of this tool, its indications and contraindications, as well as patient reviews will be discussed in detail in this article.

Indications for use of the drug

NSAIDs are used to quickly eliminate severe pain. They also have an anti-inflammatory effect, reduce body temperature. In addition, often these drugs are inexpensive, so they are widely distributed among doctors and their patients. However, each drug has its own specifics, principle of action and contraindications. That is why it is best to entrust the selection of such funds to your doctor.
Instructions for use "Ketonal DUO" indicates that the drug should be used for symptomatic therapy. Thus, he is not able to cure patients of illnesses that cause pain and inflammation. But on the other hand, for the time being, the medicine can relieve you of unpleasant symptoms, thereby facilitating your well-being.
What helps "Ketonal DUO"? As a rule, doctors prescribe it if patients have the following pathologies:
    Inflammatory and degenerative processes affecting the musculoskeletal system. The drug is prescribed for rheumatoid arthritis, osteoarthrosis, gout, chondrocalcinosis and some other diseases.
    Moderate or severe pain syndrome. Capsules help with headache or toothache. They are used for tendinitis, bursitis, radiculitis.
    Muscle pain caused by heavy physical exertion.
    Pain developed after injury or surgery. Also, the drug can be prescribed to patients with a malignant tumor in order to relieve pain and ease their well-being.
    Algomenorrhea. This is the pain that occurs in women during menstruation. Wrong uterus and other pathologies can cause them.

Form of release, packaging and composition

Anesthetic drug "Ketonal DUO" has only one form of release - capsules. However, there are other variations of this medicinal product that do not have a prefix in the name. They are released in the form of tablets, creams, ointments and even candles. All these types of drugs have a similar principle of action, indications and contraindications. But the prefix "DUO" means that the capsules have a special dosage, thanks to which you can take the medicine only once a day. Thus, it is an improved and more modern variation of the drug.
The anesthetic "Ketonal DUO" is produced in the form of modified release capsules. 150 mg of the active substance - ketoprofen - is contained in each of them. The composition of the drug also includes auxiliary components. These are lactose, microcrystalline cellulose, polysorbate, povidone and some others.
The capsules themselves consist of two parts - a transparent case and a blue cover. Inside them are small granules. These are the pellets having white and yellow color. About 40% of them are additionally covered with a special coating, due to which the drug retains its effectiveness for a long time. The capsule itself and its lid consist of gelatin, indigo carmine and titanium dioxide. Its size is No. 1.
Capsules are packed in special blisters. In each of them there are exactly 10 pills. In turn, blisters are sold in cartons of 1, 2 and 3 pieces. The drug is produced by the German pharmaceutical company Sandoz, which specializes in the production of generics. The cost of one package of medication will depend on the number of capsules in it, as well as the region of sale. As a rule, the minimum cost starts from 225 rubles. At the same time in pharmacies, these capsules are available only by prescription of the attending physician. Their shelf life is 2 years.


Pharmacokinetics

Instructions "Ketonal DUO" (150 mg) also calls this drug an improved version of conventional capsules. The main difference is the way in which the active substance is released from them. The improved capsules contain two types of pellets at once: standard white and coated with a special shell yellow. The first release ketoprofen within a short time after taking the capsule. Yellow pellets begin to act only after some time. Thus, with their help, the drug remains effective over the long term. Therefore, these capsules can be consumed only 1 time a day, so as not to feel pain.
The drug is well absorbed and has a high bioavailability, approximately 90%. Meal may affect the rate of absorption of the drug, slowing it down. Accordingly, the capsules in this case will act not so quickly. The drug is excreted by the kidneys. They process about 90% of the active substance. Another 10% is excreted through the intestines.

Does the drug has contraindications?

Not all patients can get rid of severe pain with the help of Ketonal DUO, as it has an impressive list of contraindications. In order not to aggravate your condition by an uncontrolled intake, it is best to consult a doctor before using capsules. Some experts in their responses and do recommend first to undergo a thorough examination in order not to harm the patient.
First of all, it is forbidden to take the drug to people suffering from hypersensitivity to ketoprofen and other auxiliary components that make up the capsules. You should also refuse the medication if the patient has a history of bronchial asthma, which is simultaneously combined with recurrent nasal sinus polyposis. It is necessary to choose another tool and people who are allergic to acetylsalicylic acid.
The instruction "Ketonal DUO" indicates that it is not allowed to take with erosive and ulcerative lesions of the stomach, which are in the acute stage. Intake of capsules in this case may trigger the onset of bleeding. Because of this, the drug can not be used in patients with the following diseases of the gastrointestinal tract:
    ulcerative colitis;
    diverticulitis;
    Crohn's disease;
    chronic dyspepsia;
    gastrointestinal bleeding or any suspicion of them.
For the same reason, it is not recommended to use capsules for people with a history of hemophilia and any other pathologies that cause a bleeding disorder.
Since the drug is metabolized in the liver and excreted through the kidneys, it is on these organs that an additional load is placed when it is taken. Therefore, it is not recommended to use capsules in patients who suffer from severe renal failure or any progressive liver or kidney disease. Taking the drug can only aggravate the patient's condition.
You can not prescribe a tool for children and adolescents under 15 years of age, since the use of capsules can adversely affect the growing body. Due to the presence in the composition of the drug lactose should not be used for people suffering from its intolerance.

Instructions for use of capsules "Ketonal DUO"

It has already been said above that the drug should be taken only once a day in order to quickly and permanently get rid of pain. Capsules should be washed down with plenty of drinking water or milk. Its volume should be at least 100 ml. It is best to take them during or after a meal, as drinking on an empty stomach can adversely affect the condition of its mucous membrane. Chewing or chewing capsules is strictly prohibited. You can not use their contents separately from the shell.
Instructions for use of capsules "Ketonal DUO" indicates that the standard dosage of the drug is 150 mg of ketoprofen per day. It is not recommended to take more pills, otherwise you will not avoid the appearance of side symptoms. The maximum daily dose of the active substance is only 200 mg. Therefore, taking two capsules per day can cause a worsening of the patient’s condition and an overdose.

What side effects may occur after starting?

As a rule, patients can easily tolerate even long-term use of the drug "Ketonal DUO", however, in some cases, their health may worsen markedly after the start of treatment. The fact is that capsules can cause unpleasant symptoms. If they are found, it is best to abandon the drug, picking up an analogue. If your state of health continues to deteriorate even after the cancellation of the reception, then you should seek the help of a doctor.
What side effects can the use of "Ketonal DUO" provoke? Most often, patients complain about the violation of the organs of the gastrointestinal tract. Patients feel nausea that appears after taking the capsule. Sometimes it can develop into vomiting. There is also pain and bloating in the stomach. Rarely appears diarrhea and constipation, gastritis. If the patient takes the drug, with a history of any lesions of the stomach, the capsules can trigger the appearance of bleeding and even perforation, as well as aggravation of ulcerative colitis.
Often there are side effects that affect the work of the nervous system. In this case, patients complain of headaches, dizziness and excessive sleepiness. They can develop paresthesia - a loss of skin sensitivity. In rare cases, patients were diagnosed with convulsions and emotional lability.
In practice, the appearance of side effects such as:
    hemorrhagic anemia;
    anaphylactic reactions, including shock;
    blurred vision and tinnitus;
    high blood pressure;
    exacerbation of the history of bronchial asthma, as well as bronchospasm;
    heart failure;
    hepatitis;
    skin rash and itching;
    swelling, including life-threatening angioedema;
    acute renal failure and others.
It is worth noting that all these symptoms appear in extremely rare cases, so do not be afraid to take this drug. In addition, it is believed that the more side effects the drug has, the better it is studied.


Symptoms and treatment of overdose

When taking more than 200 mg of the active substance per day overdose may develop. It can be determined by the corresponding symptoms that are characteristic of all NSAIDs. Patients begin to complain of severe nausea, which develops into vomiting over time. Moreover, in severe cases, it may be with blood. A person's stomach starts to hurt badly, melena appears - unformed feces of black color with an unpleasant odor. If you do not seek medical help in time, the symptoms begin to worsen. The patient is diagnosed with impaired consciousness and respiratory depression. Convulsions appear, and later severe renal failure develops, since the organs cannot cope with the withdrawal of a large amount of the active substance from the body.
Instructions for use of tablets "Ketonal DUO" indicates that in case of accidental overdose, it is necessary to immediately wash the stomach, and then give the patient activated charcoal to slow the absorption of the drug. You must also seek the help of a doctor. Specialists will prescribe symptomatic therapy to the patient, as a rule, taking medications that reduce the secretion of the stomach walls. In the diagnosis of renal failure, hemodialysis is necessary to help the body quickly remove ketoprofen from the body.

Taking the drug during pregnancy and lactation

Far from all patients tolerate the use of ketoneal DOW painkillers. Therefore, doctors do not recommend taking it to children under 15 years old, as well as the elderly. Pregnant women are also at risk. The inhibition of prostaglandin synthesis negatively affects the fetus in the womb of the expectant mother. Scientists have conducted a study proving that taking the drug in the early stages can trigger a miscarriage. Also, when using the drug during pregnancy increases the risk of heart disease in a child.
Therefore, taking the capsules during the first and second trimester is not recommended. They are prescribed only if the likely benefit from the reception will be significantly higher than the possible risks of complications. In the third trimester, the use of capsules is strictly contraindicated. The fact is that their active substance can provoke a weakening of the uterine generic activity. It also rarely causes premature closure of the ductus arteriosus.
No studies proving the safety of taking Ketonal DUO during breastfeeding have been conducted. Doctors can not yet say for sure whether ketoprofen is secreted along with mother's milk. Therefore, during lactation is recommended to abandon the use of capsules. If you still decide to take the drug, it is necessary to transfer the child to an artificial mixture.

special instructions

Instructions for use "Ketonal DUO" (150 mg) indicates that prolonged use of the drug has a strong effect on the body. Therefore, patients who use capsules for more than two weeks should regularly monitor the condition of the blood. Also, doctors should monitor the work of the kidneys and liver, since these organs are responsible for the metabolism of the drug and its removal from the body. At risk are patients over 65 years of age. In patients suffering from hypertension and other pathologies of the cardiovascular system, pressure should be monitored, not allowing it to increase.
Ketoprofen has not only analgesic, but also anti-inflammatory effect. Therefore, with regular admission, it can mask the symptoms of infectious diseases developing in the body.
Patients taking capsules are allowed to drive vehicles and do work that requires high mental concentration. However, when side effects occur, such as dizziness, it is best to refuse these classes.

Drug interactions with other drugs

The simultaneous use of "Ketonal DUO" (150 mg) with other drugs may affect their effectiveness, so you should discuss the possible consequences with your doctor. As a rule, NSAIDs weaken the effect of blood pressure lowering drugs and diuretics. On the contrary, capsules can enhance the effect of anticonvulsant and hypoglycemic agents, so they need to be used with caution.

Positive reviews about Ketonal Duo

Often, patients before starting a drug prefer to get acquainted with the reviews of people who have already been treated. Capsules "Ketonal DUO", as a rule, receive positive feedback. Both patients and doctors praise them. They note its high efficiency. Capsules are able to quickly remove even a very strong pain, facilitating the condition of a person. They liked that the drug acts longer than its counterparts. After drinking the capsule in the morning, the patient feels satisfactory throughout the day. The pain does not prevent him from working or doing household chores. In addition, in the reviews of "Ketonal DUO" people indicate that it is well tolerated. Side effects are quite rare, even if you drink more than one capsule per day, but two. In addition, the drug has an anti-inflammatory effect on the body. Patients indicate that the capsules are small, so it is convenient to swallow them. Most often they are consumed in the morning after a hearty breakfast so as not to harm the stomach lining.

Negative reviews

But not all patients were satisfied with the use of Ketonal DUO tablets. Some of them in their negative reviews indicate that the drug was not effective enough. He eliminates the pain, but after a few hours she returns. And you cannot drink another capsule, because otherwise the patient will exceed the daily dosage. Therefore, people have to endure the pain, and then move on to another effective remedy. In the reviews, they indicate that instead of the promised 24 hours, capsules are only about 5-7. Also, patients in the reviews write that after the reception, they noticed a deterioration in their own well-being. Most often, they suffer from nausea, headaches and discomfort in the stomach. After the capsules are taken, these symptoms disappear. The high cost of the drug is another major drawback. Because of it, some patients can not afford to constantly use this painkiller. Therefore, they are forced to select a more budget equivalent. Doctors in a review note that the drug has a negative effect on the state of the gastrointestinal tract, so it is not worthwhile to use it for a long period. Otherwise, complications may occur.
This article has been reviewed in detail the instruction to "Ketonal DUO" (150 mg). We can say that this is a modern drug with high efficiency. If you take it properly, adhering to the recommendations of the doctor, you can reduce the risk of adverse symptoms to a minimum.

Terms of sell

You don't need a prescription to buy Ketonal Duo.