Indometacin supp 100mg #10

Indometacin instruction

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Release form and composition

The drug is available in the form of torpedo-shaped rectal suppositories. The active ingredient of the drug is Indometacin. Each Suppository contains 100 mg of active ingredient. The inactive component of Indometacin is corn starch and fat.
The drug can be produced in the form of Suppositories, containing 50 mg of active ingredient.

Pharmacological action of Indometacin

The drug belongs to the group of nonsteroidal anti-inflammatory drugs. Indometacin provides analgesic, antipyretic and anti-inflammatory effect. The active substance prevents the synthesis of prostagladins, platelet aggregation.
    The drug reduces swelling of tissues after trauma, surgery, relieves pain arising from movement or at rest.
After rectal administration of suppositories, Indometacin is rapidly absorbed from the rectum. Metabolization of the drug is carried out by the liver.
The half-life is 4-9 hours. Metabolites are excreted in the urine; unchanged part of Indometacin is excreted in the feces. Dialysis does not provide drug withdrawal, the active substance is able to penetrate into breast milk.

Indications for use Indometacin

The drug is recommended to be prescribed as part of complex therapy for:
    headache and toothache;
    pathologies of the musculoskeletal system (psoriatic, rheumatoid, juvenile arthritis or ankylosing spondylitis, gout);
    diseases of ENT organs (external otitis, inflammation of the middle ear, acute tonsillitis, sinusitis, laryngitis, pharyngitis);
    varicose veins;
    neuralgia;
    rheumatic soft tissue damage;
    inflammatory processes in the urogenital system (cystitis, prostatitis).
Perhaps the appointment of dysmenorrhea, the nature of which can not be established.

Mode of application

Suppositories enter 1 time in knocks. It is recommended to clean the intestines before the procedure; if necessary, put an enema. The suppository is injected deep into the rectum, taking a pre-posture lying on its side. The duration of the course is determined by the attending physician.
To relieve gout attacks, the instruction recommends the use of Suppositories, 1 pc each. twice a day.

Side Effects of Indometacin

Taking the drug can cause:
    Malfunctions of the digestive system. The patient complains of nausea, vomiting, pain in the abdomen, loss of appetite. Long-term use may provoke gastric ulcer and duodenal ulcer.
    Negative response from the nervous system. The patient has general weakness, drowsiness, sleep disturbances, dizziness, and increased fatigue.
    Distortion of perception of the environment by the senses. This group includes conjunctivitis, changes in hearing, tinnitus, decreased vision and hearing.
    Persistent increase in blood pressure, tachyarrhythmias. Long-term use may cause heart failure.
    Nephrotoxic effects.
    Thrombocytopenia, bleeding, anemia, leukopenia.
    Allergic reaction, which manifests as itching, urticaria, angioedema, anaphylactic shock.
    Hyperglycemia, hyperkalemia, increased sweating.
    Aseptic meningitis.
Indometacin can also cause aggravation of hemorrhoids.

Contraindications

The drug is not prescribed to patients with such pathologies of the digestive system organs:
    digestive tract ulcer;
    ulcerative colitis;
    gastrointestinal bleeding;
    cirrhosis of the liver;
Indometacin is contraindicated in patients with concomitant diseases of the cardiovascular system:
    heart disease;
    heart failure;
    thrombocytopenia.
It is not recommended to prescribe the drug in the presence of such ophthalmic pathologies:
    optic nerve disease;
    distortion of color perception.
Other contraindications include:
    lack of coordination;
    hemorrhoids in the acute stage, proctitis;
    renal failure;
    pregnancy and lactation;
    age under 18;
    intolerance to the components that make up.
Care must be taken when prescribing Indometacin to patients with epilepsy, parkinsonism.

special instructions

Therapy requires constant laboratory tests to evaluate the performance of the liver and kidneys. When changing indicators, dose adjustment is necessary in elderly patients and patients with impaired renal function.
At the time of therapy, it is recommended to abandon the management of complex mechanisms, perform tasks that require a high concentration of attention.

Use during pregnancy and lactation

Contraindicated.

Use in children

Indometacin is contraindicated for use in pediatric practice.

Overdose

Taking the drug in large doses can cause severe headache, nausea, vomiting, confusion, memory lapses.
    In severe cases, overdose causes convulsions or numbness of the limbs.
The appearance of the described symptoms requires seeking qualified medical assistance.
Therapy is carried out under the supervision of the attending physician, taking into account the symptoms and their severity.

Drug interactions

Indometacin reduces the effectiveness of diuretic drugs. The drug enhances the action of antiplatelet agents and anticoagulants.
When taken simultaneously with hormonal drugs, corticosteroids increase the risk of the development of pronounced side effects of two drugs. Glucocorticosteroids, ethanol, paracetamol, when taken together with the drug, increase the risk of exacerbations of chronic pathologies of the digestive system, bleeding from the digestive tract. Simultaneous use with zidovudine increases the toxic effects on the body.

Terms and conditions of storage

Indometacin is stored at room temperature. Shelf life is 3 years.

Reviews

Ivan, 30 years old
Suppositories were prescribed to treat neuralgia. Prior to that, he used drugs in the form of tablets and ointments, but did not achieve the expected effect. Indometacin quickly relieves pain. He put Suppositories before bedtime, an hour later he could sleep, turn without fading from acute pain. The course lasted a week. Of the side effects observed nausea, stomach pain, dizziness. All unpleasant symptoms disappeared on their own after drug withdrawal.
Evgenia, 42
Suppositories were prescribed for angina. Indometacin effectively copes with fever, muscle pain, inflammation. The drug acts quickly. I'm not sure that weakness, nausea, poor appetite, lack of coordination were side effects of the medication, perhaps it was the body’s response to the disease.
Vera, 49 years old
Suppositories used to relieve acute toothache during the trip to rest. Opportunities to contact a dentist was not. 2 days escaped with this medicine; helps quickly, acts for a long time. She was afraid of side effects, but did not notice any unpleasant changes in her body. At the reception at the dentist she warned that she had used the medication for 2 days, he reassured that it would not hurt treatment.

Terms of sell

You don't need a prescription to buy Indometacin.