Flamadex tabs 25mg #10

Instruction for Flamadex

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The analgesic effect occurs within half an hour after application and lasts:
    after taking the pill - 4-6 hours;
    after parenteral administration of 50 mg - 4–8 hours.
Using Flamadex in combination with opioid analgesics can reduce the dose of opioids by up to 45%.

Indications for use

What does Flamadex help? According to the instructions, the drug is prescribed in the following cases:
    symptomatic treatment of diseases of the musculoskeletal system, inflammatory-degenerative and inflammatory nature, or due to impaired metabolic processes (acute and chronic course): osteoarthritis, rheumatoid arthritis, spondyloarthritis - psoriatic arthritis, reactive arthritis, ankylosing spondylitis;
    relief of pain, of different origin: pain in injuries, in the postoperative period, with bone metastases; renal colic, sciatica, ischialgia, algomenorrhea, neuralgia, toothache.
It does not affect the progression of the disease - it is indicated only for symptomatic treatment, reduction of inflammation and pain at the time of use.

Instructions for use Flamadex dosage

Tablets are taken orally during the meal, drinking clean water.
The recommended dosage of Flamadex according to the instructions for use, depending on the evidence and degree of pain syndrome:
    4 to 6 times a day, 12.5 mg (½ tablet);
    3 times a day, 25 mg (1 tablet).
The maximum daily dose should not exceed 75 mg (3 tablets).
Older people, as well as patients with impaired renal and / or liver activity, should begin receiving at lower dosages, the maximum daily dose is 50 mg (2 tablets).
The duration of treatment is no more than 3-5 days, the drug is not intended for long-term therapy.

Side effects of Flamadex

The instruction warns about the possibility of the development of the following side effects when appointing Flamadex:
    On the part of the digestive system: heartburn, abdominal pain; rarely - erosive and ulcerative lesions of the gastrointestinal tract.
    The nervous system: headaches, dizziness, nervousness, sleep disturbance, paresthesia.
    Since the cardiovascular system: heartbeat, increased blood pressure.
    Allergic reactions: skin rash, bronchospasm.
    Others: chills, swelling of limbs, photosensitization; rarely - a change in the pattern of peripheral blood, renal dysfunction.

Contraindications

Flamadex is contraindicated in the following cases:
    erosive and ulcerative lesions of the gastrointestinal tract (GIT) and duodenum;
    a period of exacerbation of inflammatory bowel disease (Crohn's disease, ulcerative colitis);
    a history of gastrointestinal bleeding;
    coagulation disorders, including hemophilia;
    incomplete or complete combination of recurrent nasal polyposis and paranasal sinuses, bronchial asthma, and intolerance to acetylsalicylic acid and other NSAIDs (including anamnesis);
    active bleeding of various origins, including suspected intracranial bleeding;
    concomitant anticoagulant therapy;
    marked (10–15 points on the Child-Pugh scale) abnormal liver function;
    severe renal dysfunction with creatinine clearance (CC) less than 30 ml / min, progressive kidney disease;
    confirmed hyperkalemia;
    the period after coronary artery bypass surgery;
    decompensated heart failure;
    gestation period and breastfeeding;
    age up to 18 years;
    hypersensitivity to NSAIDs (including sulfites) and drug components.
Contraindicated use in the form of a solution for IV and IM injection for neuraxial (intrathecal or epidural) administration due to the presence of ethanol in its composition.
Caution must be exercised in chronic heart failure [I – II functional class NYHA (New York Heart Association)], coronary heart disease, arterial hypertension, gastric ulcer and duodenal ulcer, Crohn's disease, ulcerative colitis, history of liver disease, hepatic porphyria, chronic renal failure (CC 30–60 ml / min), a significant decrease in circulating blood volume (including conditions after surgery), bronchial asthma, cerebrovascular disease diseases, diabetes mellitus, dyslipidemia or hyperlipidemia, peripheral arterial diseases, systemic connective tissue diseases, Helicobacter pylori infection, tuberculosis, prolonged use of NSAIDs, severe osteoporosis, severe somatic diseases, alcoholism, smoking, concomitant osteoporosis, severe somatic diseases, alcoholism, smoking, concomitant osteoporosis, severe somatic diseases, alcoholism, smoking, concomitant osteoporosis, severe somatic diseases, alcoholism, smoking, concomitant osteoporosis, severe somatic diseases, alcoholism, smoking, concomitant osteoporosis including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel), selective serotonin reuptake inhibitors (including citalopra , Paroxetine, sertraline, fluoxetine), the elderly (including those with a low body weight, concomitant diuretic therapy, or a weakened state) and allergic reactions in the anamnesis.

Overdose

Cases of overdose are not described.
Nausea, vomiting, anorexia, abdominal pain, dizziness, disorientation, headache, drowsiness are possible.
Recommended symptomatic therapy, and if necessary, hemodialysis.

Storage conditions

Store at a temperature up to 25 ° C in a dark place. Shelf life - 2 years. Conditions of sale from pharmacies - prescription.

What do the reviews say?

Reviews of doctors Flamadex, indicate a high efficacy of the drug. Patients note its rapid analgesic effect, high efficacy with moderate pain, as well as low price compared with analogues.
As disadvantages reviews indicate the presence of a large number of contraindications and side effects, relatively short action and pain injections.

special instructions

It should be used with caution in patients with a history of allergies.
Care must be taken when prescribing Flamadex to patients with disorders of the gastrointestinal tract or gastrointestinal diseases in history. In the event of gastrointestinal bleeding or ulcers, drug therapy should be canceled.
It has been clinically proven that the simultaneous use of Flamadex and drugs of low molecular weight heparin in prophylactic doses in the postoperative period does not change the clotting parameters. However, when used with other drugs that affect blood clotting, careful medical monitoring of the blood clotting system is necessary. Dexketoprofen may cause reversible inhibition of platelet aggregation.
Like other NSAIDs, it can lead to an increase in creatinine concentration and plasma nitrogen content. Like other prostaglandin synthesis inhibitors, Flamadex can have a side effect on the urinary system, which can lead to the development of glomerulonephritis, intestinal nephritis, papillary necrosis, nephrotic syndrome and acute renal failure.
As with the use of other NSAIDs, there may be a slight transient increase in some indicators of liver function, a significant increase in the activity of AST and ALT in serum. At the same time, the control of liver and kidney functions is necessary in elderly patients. In the case of a significant increase in the relevant indicators of the drug should be canceled.
Flamadex should be used with caution in patients with chronic heart failure I-II functional class according to NYHA.
Like other NSAIDs, it can mask the symptoms of infectious diseases. Reported single cases of exacerbation of infectious processes localized in soft tissues with the use of NSAIDs. Therefore, medical supervision of patients with signs of bacterial infection or deterioration during dexketoprofen treatment is required.
Due to the possible dizziness and drowsiness during treatment, a decrease in the ability to concentrate and the speed of psychomotor reactions is possible.

Terms of sell

You don't need a prescription to buy Flamadex.