Moviprep powder #2

Instruction for Moviprep

You can buy Moviprep here

Distinctive properties of the drug Moviprep

With Moviprep, the preparation of the colon becomes a comfortable colonoscopy.
Unlike other drugs, Moviprep has a pleasant taste due to the addition of ascorbic acid to the composition. The drug has excellent tolerance.
Only 4 liters of liquid are used, 2 liters of the composition with the taste of the Moviprep preparation and 2 liters of clear food liquids: it can be non-greasy transparent broth, black tea weak without milk, stewed fruit without berries, clarified juice without pulp, non-alcoholic unpainted transparent drinks, water.
For the action of each liter of the composition of the drug, an average of 2 hours is required. While taking the drug, it is recommended to perform light physical exercises: circular rotation of the pelvis, tilting to the sides, forward, backward, squats. It is possible to perform household work - wiping dust off furniture, vacuuming, moving things from place to place.
The criteria for the patient's readiness for intestinal endoscopy are the appearance of a liquid of a transparent nature or slightly colored yellow.
It is necessary to take into account the appropriate time interval for a trip to the clinic for colonoscopy. It is possible to prepare in a ward in a clinic if medical personnel are warned about this in advance and there is such an opportunity in a medical institution.
Moviprep by its principle of action refers to laxatives.

Composition and form of release

The drug Moviprep is available in powder form for the preparation of a composition for oral administration. The appearance of sachet A varies from white to yellow, has a lemon aroma. The mass in one bag is 111.896 g of powder. The appearance of sachet B varies from white to light brown. Weight in one bag is 10.6 g of powder. The drug is available in a cardboard box, in which two plastic bags with one sachet A and one sachet B.
1 sachet A includes macragol-3350 100 g, sodium sulfate 7.5 g, sodium chloride 2.691 g, potassium chloride 1.015 g, auxiliary components: aspartame, potassium acesulfame, lemon flavor V3938-1 N1.
1 sachet B contains ascorbic acid 4.7 g, sodium ascorbate 5.9 g.
In a cardboard bundle there are two plastic bags of one sachet A and B, 111.896 and 10.6 g respectively.

Pharmachologic effect

The resulting composition when taken orally has the following pharmacological effect - electrolytes, which are based on macrogol, provoke medium-intensity diarrhea and rapid cleansing of the large intestine.
Included in the composition of macrogol-3350, sodium sulfate and ascorbic acid have an osmotic effect on the body, which provokes a laxative effect.
The medicinal effect of the substance macrogol-3350, as a result, increases the amount of feces. In turn, this leads to an increase in the intensity of the wave-like contraction of the intestinal walls.
Disruption of the water-electrolyte balance in the body does not occur due to the additional intake of fluid and the presence of electrolytes in the preparation.

Pharmacokinetics

During a stay in the intestine, the laxative Macragol-3350 does not change. In addition, it is almost not absorbed from the digestive tract. The withdrawal of the absorbed substance Macragol-3350 is via the kidneys.
The absorption of ascorbic acid occurs in the small intestine through active sodium-dependent saturated transport. It is worth noting that when taking this drug, there is an inversely proportional relationship between the percentage of absorbed substance on the dose and, directly, the dose of the drug received. When taken orally in a dose of 30 mg to 180 mg, about 70-85% of the dose is absorbed. During the next consumption of ascorbic acid in a volume of up to 12 g, only 2 g are absorbed by the body through the oral method.
In the case of taking large doses of ascorbic acid and exceeding its saturation in plasma of 14 mg / l, the absorbed ascorbic acid is excreted as a whole not modified by the kidneys.
Indications
The main indication for taking this drug is the preparatory component for endoscopic, radiological and other diagnostics and studies. In addition, this drug is taken in cases of surgical intervention that require bowel movement.

Dosage regimen

Moviprep is administered orally inward.
To prepare 1 liter of the composition, you need to pour the contents of one sachet A and one sachet B into a small amount of water. After completely dissolving the contents of the two sachets, you need to bring the entire volume of the composition to 1 liter. The second liter of the composition for oral administration is prepared in a similar way. It is believed that powders should be diluted only with water and avoid sodas during preparation. But according to the recommendations of American doctors, to improve the palatability, it is possible to dilute Crystal Light Lemonade / Orange or Lemon-Lime Gatorad, PowerAde, Sprite, 7-Up with lemonade. Perhaps studies were conducted that showed that sports electrolyte drinks such as Gatoreid (which are commercially available in Russia) and lemonade do not change the structure of the macrogol.
The total dosage of Moviprep is 2 liters of the composition for oral administration. The resulting composition can be used in the form of a single dose (as stated by the manufacturer), and in two doses (recommendations of international endoscopic communities). For a single use of a laxative, you must either use 2 liters of the composition in the evening before the day of the procedure, or 2 liters of the composition in the morning on the day of the procedure. To take the composition twice, you need to use 1 liter of the composition in the evening before the day of the procedure and 1 liter of the composition in the morning on the day of the diagnostic procedure.
If surgery is planned, the drug should be used once in a volume of 2 liters in the evening before the day of the diagnostic procedure.
The resulting composition should be consumed no later than 1-2 hours after preparation. For the best effect of a laxative, it is necessary to drink at least one liter of another liquid (water, fruit juice without pulp, tea, coffee) together with the use of the drug. In no case should you drink alcohol during preparation.
In case of separate (1 liter in the evening before the day of the procedure and 1 liter in the morning on the day of the procedure), the use of the drug and other fluids must be completed at least 3 hours before the start of the diagnostic procedure itself.
In the case of a single morning reception, the use of the drug and other fluids must be completed at least 3 hours before the start of the diagnostic procedure itself.
In addition, patients need to keep in mind the time it takes a trip to the clinic to carry out the procedure.
From the beginning of taking the drug Moviprep until the end of the diagnostic procedure, you can not eat any solid food.

Side effect

Like many drugs, the laxative Moviprep has some side effects. Among them, diarrhea and moderate-intense bowel movements are a specially caused effect. This effect is necessary to cleanse and prepare the intestines for subsequent diagnosis. Due to the effect of the drug, some undesirable effects can be observed, such as nausea, vomiting, bloating, abdominal pain, irritation in the anus, and some sleep disturbances. Also, due to diarrhea and vomiting, excessive fluid loss by the body can be observed.
In addition to the above side effects, there is the likelihood of various allergic reactions, including rash, urticaria, itching, Quincke's edema and anaphylactic shock.
There are also violations from various aspects of the aspects of the body. Undesirable effects are classified by frequency, where very often it is over 1/10 cases, often from 1/100 to 1/10 cases, infrequently from 1/1000 to 1/100 cases, rarely from 1/10 000 to / 1,000 cases, very rarely less than 1/10 000 cases and cases with an unknown frequency of manifestation.
On the part of the immune system, the frequency of manifestations of effects such as allergic reactions, including anaphylactic reactions, dyspnea, and skin reactions, is unknown.
Mental disorders occur frequently in relation to sleep disturbance.
On the part of the nervous system, manifestations of effects such as dizziness and headache are often observed; effects may also be present whose frequency is unknown, namely, convulsions associated with an insufficient concentration of potassium ions in the blood.
On the part of the metabolism, the frequency of manifestations of effects such as dehydration, electrolyte disturbances, including a decrease in the level of bicarbonate in the blood, an excess or lack of calcium in the blood plasma, a lack of phosphates, potassium and sodium in the blood, and a change in blood chloride levels are unknown.
On the part of the cardiovascular system, the frequency of manifestations of such effects as a short-term increase in blood pressure, arrhythmia, heart palpitations is unknown.
From the gastrointestinal tract, the manifestation of such effects as abdominal pain, nausea, bloating, irritation in the anus is very common; vomiting, digestive upset; difficulty swallowing - infrequently; in addition, for effects such as flatulence and vomiting, the frequency of manifestation is unknown.
On the part of the liver and biliary tract, undesirable effects such as deviations from the norm of functional liver tests are rarely observed.
On the part of the skin and subcutaneous tissues, the frequency of manifestation of such undesirable effects as allergic skin reactions, including angioedema, urticaria, pruritus, rash and redness of the skin is unknown.
General reactions of the body such as malaise, fever are observed very often; chills, thirst, hunger - often; and simple discomfort in patients is observed infrequently.
If any of the above unwanted effects worsen, you should immediately consult a doctor.

Contraindications

As with any other drug, there are a number of contraindications for use.
Therefore, Moviprep cannot be taken if the patient has:
    individual intolerance to any of the components that make up the laxative;
    violation of the motor function of the stomach;
    intestinal obstruction;
    violation of the integrity or risk of this violation of the organs of the gastrointestinal tract;
    violation of the metabolism of amino acids (due to the content of aspartame);
    lack of glucose-6-phosphate dehydrogenase (due to the content of ascorbic acid in the composition);
    severe inflammatory bowel disease or toxic megacolon, which is a complication of severe inflammatory processes in the intestine, including Crohn's disease and ulcerative colitis;
    this laxative is contraindicated in children under 18 years of age;
    unconsciousness.
This drug should be taken with caution if the patient has the following disorders:
    impaired vomiting reflex, a tendency to aspiration or with impaired movement of fluids and gases in the intestine;
    impaired consciousness;
    dehydration of the body;
    severe heart failure (III-IV FC according to NYHA classification);
    severe renal failure (CC <30 ml / min);
    severe acute inflammatory diseases;
    unclear cause of abdominal pain;
    risk of heart rhythm disturbance, for example, patients receiving treatment for cardiovascular disease or having thyroid disease.
In the presence of one of the above deviations before taking the laxative Moviprep, the training course should consult a doctor.

Pregnancy and lactation

This laxative should be taken with caution during pregnancy or breastfeeding. With breastfeeding, the use of the drug is limited. In case of pregnancy, the use of the drug is possible when the predicted benefit to the mother outweighs the risk to the fetus. Please note that in any case, you must consult a doctor.

Use for impaired renal function

In case of impaired renal function, including with severe renal failure, the drug should be taken carefully, after consulting with a doctor.

Use in children

For children under 18 years of age, this laxative is contraindicated.

Use in elderly patients

Elderly patients are only allowed to take this drug with the watchful eye of doctors.

Special instructions

In order to start taking this drug, it is necessary to adhere to some special instructions to a certain circle of patients.
Thus, elderly patients, weakened patients with different parallel ailments, patients predisposed to aspiration or with impaired movement of fluids and gases in the intestine, with impaired consciousness, especially in the case of the introduction of a laxative through a nasogastric tube, this drug must be taken under control a doctor.
It should be noted that the prepared composition of the product does not replace daily fluid intake. This means that in parallel with taking the drug, it is imperative to use the daily rate of fluid.
Also, for weakened patients, patients with different parallel ailments, with serious impaired renal function, heart rhythm disturbance and the risk of electrolyte balance failure in the body, it is necessary to monitor the level of electrolytes at all stages of treatment, conduct a study of kidney function and perform an electrocardiogram.
In patients who have risks associated with the cardiovascular system and electrolyte imbalance, a serious disturbance of the heart rhythm was rarely observed. This is due to the use of ion osmotic laxatives, which include the drug Moviprep.
If the patient exhibits one of the symptoms that speak of arrhythmia or a violation of the water or electrolyte balance, it is necessary to conduct all related studies and treat all the symptoms.
If severe flatulence, bloating, abdominal pain or other undesirable reactions appear that make it difficult to take the drug later, you need to slow down or temporarily stop taking it and consult a specialist. In the case of preparing patients who follow a diet that controls the sodium content in foods, it must be borne in mind that the composition of the product includes 56.2 mmol of absorbable sodium per liter of prepared solution.
In the case of preparation of patients with impaired renal function or patients following a diet that controls the potassium content in products, it must be borne in mind that the composition of the product includes 14.2 mmol of potassium per 1 liter of prepared composition.
The effect on the patient of the drug in the management of mechanisms and vehicles was not identified.

Overdose

Excessive use of the drug manifests itself in the form of a symptom such as severe diarrhea. To avoid disturbance of the water-electrolyte balance, it is necessary to use a large amount of liquid, preferably fruit juices. In more severe cases, the introduction of infusion formulations is necessary.

Drug interaction

Diarrhea provoked by the use of the laxative Moviprep can lead to impaired absorption and absorption of other drugs taken in parallel. In addition, any medications taken by the oral method for one hour before the laxative interaction of the drug have a chance of elimination from the gastrointestinal tract without being absorbed.

Terms and conditions of storage

Keep the drug Moviprep out of the reach of children at room temperature. The shelf life of this drug is 3 years.
The reconstituted composition must be stored at a temperature not exceeding 8 ° C. In this case, the shelf life is reduced to 24 hours.

Reviews

Irina
This procedure overtook me suddenly, for a long time did not want to go to the doctor, but thank God it went. The doctor ordered preparing for endoscopic examination and, possibly, surgery. It was prepared by Moviprep, the study went well, the operation was also successful, the doctor praised.

Terms of sell

You can buy Moviprep without a prescription.