Losec MUPS tabs 20mg #28

Instruction for Losec MUPS

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Some facts

For diseases associated with damage to the gastric mucosa with subsequent formation of ulcers, a chronic type of development and cyclical recurrence are characteristic. An ulcer is a type of pathology, as a result of which, on the surface of the stomach or duodenum, affected areas are noted. Middle-aged men are at risk, although, of course, women are prone to this ailment.
The disease is characterized by a regular renewal of symptoms, which alternates with the moments of "retreat" of the disease. Most often, a chronic ulcer worsens in the fall and spring, when the body weakens due to a lack of vitamins and sunlight.
Interestingly, stomach ulcers develop less frequently than in the duodenum.
The key factor in the formation of ulcers is a specific microorganism that affects the mucous membranes, but its activity is activated due to a number of factors. For example, constant stress, anxiety, depression significantly increase the likelihood of symptoms. Improper nutrition is an important risk factor. This is especially true of spicy and rough food, which affects the mucous membranes. A number of bad habits (smoking, alcohol, dependence on pharmacological drugs) also destroy the mucous membrane.
That is why ulcers develop so often. This drug is an effective tool for the treatment of defects in the mucosa.

Pharmacological properties

Losec MUPS belongs to the group of anti-ulcer drugs.
The main feature of Losec MUPS is that it specifically suppresses the activity of the proton pump in some structures of the gastrointestinal tract. Consequently, the production of perchloric acid slows down, while stimulated and unstimulated secretions are inhibited. This process is independent of the type of inductor.
Over the four days of the course, maximum suppression of both daytime and nighttime release of perchloric acid will already be achieved. The daily acidity when taking 20 mg of the active substance gradually decreases by at least 80% and remains stable after canceling the course.

Composition and form of release

Each tablet has a special structure that helps preserve the properties of the active component in an aggressive environment. One tablet contains omeprazole in various dosages. Cellulose microcrystals, monostearin, E-463, E-464, magnesium salt of stearic acid, isobutanoic acid, sucrose, wax, E433, nonionic surfactants, PVP cross-linked, sodium stearyl fumarate, natural talc, triethyl citrate, are added as auxiliary microcrystals. E 172, E 171.
On sale you can find bottles of various volumes (7, 14, 28 pills). Tablets with different concentrations of the active ingredient also differ externally.
10 mg tablets: powdery, convex on both sides, oblong. Each tablet is coated with a special protective coating. 10 mg is printed on one surface and the company logo is printed on the other.
20 mg tablets: pale pink, convex on both sides, elongated, covered with a protective sheath, oblong, in a protective sheath. 20 mg is printed on one surface and the company logo is printed on the other.
40 mg tablets: brick red, convex on both sides, elongated, covered with a protective shell, oblong, in a protective shell. A 40 mg print is printed on one surface, and the company logo on the other.

Instructions for use

Experts recommend taking the pill of Losec MUPS in the morning, not chewing, but swallowing whole. If the patient has difficulties with this, then the Losec MUPS tablet is dissolved in acidified water. Such a solution should be drunk within half an hour.
12 duodenal ulcer Patients in whom the disease is in the acute phase are recommended to take one tablet (20 mg) every day for two weeks. If there is no improvement during this period, then the course is extended for another two weeks. In cases where it was found that the form of the ulcer is resistant to treatment, a monthly course of tablets of 40 mg of the active substance is prescribed. The instructions also indicate a scheme for the prevention of relapses: once a day, one tablet (10 mg).
Gastric ulcer: take one tablet (20 mg) every day for a month. If effectiveness is not observed, the course is repeated. For cases of resistive forms - one and a half months, you need to take one tablet every day with a dose of 40 mg of active substance. Prevention can also be: 20 mg of active substance per day.
Gastric ulcer or erosion of the duodenum associated with non-steroidal anti-inflammatory drugs: Take 20 mg once a month for a month. An additional course lasts 4 weeks.
Destruction of the pathogen microorganism. A special three-component therapy system has been developed for this disease.
Losec MUPS (20 mg) is taken together with amoxicillin (1 g) and clarithromycin (500 mg). Each remedy is consumed twice a day for a week.
A similar property has another scheme. Losec MUPS (20 mg) with metronidazole (400 mg), which can be replaced with tinidazole (500 mg), and clarithromycin (250 mg). The indicated funds should also be taken twice a day for a week.
The two-component therapy system involves a different set of drugs: these tablets (40 mg) are combined with amoxicillin (1.5 g) every day for two weeks. If necessary, the dosage is divided into several doses.
If after treatment using any of these systems, the analysis of the pathogen is positive, then the course is repeated.
Reflux esophagitis: For a month, it is recommended to take tablets in a dosage of 20 mg once a day. In the absence of effect, the course is repeated. Depending on the form of the disease, the dosage can be increased, as well as the duration of the course (up to 40 mg for a month and a half). To maintain remission, 10 mg of the active ingredient is consumed every day.
Dyspepsia against the background of increased secretion of gastric juice. The doctor can adjust the dosage from 10 to 20 mg per day. The course lasts a month. If the symptoms do not go away after a month, then repeated tests should be performed.
Zollinger-Ellison syndrome: for each case, the dosage is selected individually, but not more than 60 mg per day. If the doctor has determined that the syndrome is severe, then you can increase the dose to 120 mg per day. It is worth noting that doses of more than 60 mg are divided into two uses.

Indications for use

The instructions for use say that Losec MUPS can be prescribed for ulcers (both stomach and duodenum, peptic forms), reflux esophagitis, Zollinger-Ellison syndrome, local pain caused by acids and a number of other diseases, if, at the discretion doctor, there is such a need.
Classification of diseases according to ICB-10: K21 Gastroesophageal reflux, K25 Gastric ulcer, K26 Duodenal ulcer, K27 Peptic ulcer, K30 Dyspepsia, K86.8.3 * Zollinger-Ellison syndrome.

Adverse reactions

Nervous system and sensory organs. migraine, dizziness, numbness, tingling sensation, goosebumps, sleep disturbances, confusion and a change in state of consciousness, increased excitability, depression (only if the patient has a predisposition to this), diffuse degenerative changes in brain structures due to severe liver diseases .
Gastrointestinal tract: digestive disorders, local pain, vomiting, bloating, changes in the properties of liver enzymes, dry mouth, stomatitis, fungal infections, impaired functions and inflammatory processes in the liver, nausea.
Leather. rash, itching, sensitivity to sunlight, acute inflammatory processes on the skin, hair loss.
Musculoskeletal system: joint pain, hypertonicity with subsequent pain, muscle weakness.
Heart, blood vessels, blood. Violations of the formation of white blood cells, platelets, a decrease in their concentration.
Allergy. Urticaria, Quincke's edema, a sharp increase in body temperature, nephritis, anaphylactic shock.

Contraindications for use

For patients who have been found to be hypersensitive to any of the components, it is better to choose other means for therapy.

Storage Features

Store Losec MUPS at room temperature (not more than 25 degrees Celsius) for three years. After three years from the production of the capsule is forbidden to use!

Use during Pregnancy and Breastfeeding

Pregnant women may be prescribed Losec MUPS, but only after consulting a specialist. It is better for women who are breastfeeding to either refuse breastfeeding or to choose other means for therapy, because there is a risk that the active and auxiliary components are extracted with milk.

Alcohol compatibility

It is undesirable to combine the course of the drug with the use of alcohol. This is due to the additional burden on the stomach.

Drug interactions

There are a number of drugs that are not used with Losec MUPS. These include, for example, diazepam, warfarin, phenytoin. This is due to the fact that their release is slowed down by the active component of the drug. Also, plasma levels of clarithromycin significantly increase with the use of this drug.
You should not combine HIV protease inhibitors (for example, atazanavir and nelfinavir) with Losec MUPS. The active substance of this agent reduces the level of inhibitors in plasma. Theoretically, this process is possible due to sharp changes in the hydrogen index.
Losec MUPS is not recommended for those who use clopidogrel. Studies were conducted, which revealed that the exposure to clopidogrel secretion decreases along with inhibition of platelet adhesion.
Due to the decrease in acidity by Losec MUPS, the absorption of a number of drugs in the stomach is markedly reduced (for example, itraconazole, ketoconazole and erlotinib).
On the other hand, an increase in the pH of the medium stimulates the absorption of digoxin and other substances of this group.
Omeprazole does not interact with active components, the metabolism of which occurs with the participation of isoenzymes.

Therapy Features

Before you start taking Losec MUPS, you need to take tests for the presence of malignant tumors. The fact is that therapy masks the symptoms of the presence of malignant tumors and complicates the subsequent diagnosis.
For elderly patients and those whose kidney function is impaired, dose adjustments are not needed.
If the patient has impaired liver function, then the bioavailability of omeprazole increases. Therefore, 10-20 mg of the active substance will be sufficient.

Terms of sell

You don't need a prescription to buy Losec MUPS.