Enterofuryl caps 200mg #16

Instruction for Enterofuryl

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Enterofuryl is a drug from the group of broad-spectrum antimicrobial drugs. The drug does not have a systemic effect, it is prescribed for the treatment of infectious diarrhea. The active ingredient is nifuroxazide, a 5-nitrofuran derivative. Enterofuryl has a bactericidal, bacteriostatic effect, is active against many causative agents of gastrointestinal infections. The antimicrobial effect of the drug is dose-dependent, while low, medium doses have a bacteriostatic effect, high - bactericidal.
The bacteriostatic effect of Enterofuryl is associated with inhibition of the activity of dehydrogenase, while the biosynthesis of the necessary compounds in the bacterial cell is disrupted. As a result, the respiratory chain is blocked, the tricarboxylic acid cycle is inhibited, and the bacterial cell loses its ability to multiply.
The bactericidal effect of Enterofuryl is due to the ability of high doses of the drug to destructively affect the membrane of bacterial cells. As a result of the violation of the integrity of the cell membrane, the death of the bacterium occurs.
Also Enterofuryl is able to inhibit the production of exotoxins by pathogenic bacteria, as a result of which irritation of the cells of the intestinal epithelium decreases and the production of fluid into the lumen of the gastrointestinal tract decreases.
By increasing the phagocytic activity the drug activates the immune system.
The drug does not have a depressing effect on non-pathogenic flora, and therefore dysbacteriosis does not occur during its use.
After oral administration, the drug is not absorbed in the gastrointestinal tract, there is no systemic effect. A high concentration of the drug is created in the intestine. Enterofuryl is excreted in the feces.
Due to the high clinical effectiveness, reviews of the drug are positive. In addition to the good effect in bacterial infections of the gastrointestinal tract, the drug also reduces the risk of bacterial superinfection in viral diarrhea, therefore, in this pathology, the appointment of Enterofuryl is also advisable.

Indications

According to the instructions for the drug, the indications for its appointment are:
    acute, chronic diarrhea of ​​bacterial etiology (if there are signs of helminth invasion, the drug is not used);
    chronic diarrhea with colitis;
    iatrogenic diarrhea due to the administration of antimicrobial drugs;
    according to the indications, the drug can be prescribed for diarrhea of ​​not specified etiology.

Contraindications

According to the instructions for Enterofuryl, this drug is contraindicated in case of hypersensitivity to nifuroxazide or other nitrofuran derivatives, in childhood (up to 1 month). The drug is not used to treat premature babies, in encapsulated form - under the age of 7 years.

Method of application, dosage

For the treatment of patients older than 7 years, the drug is used in the form of capsules and suspensions. Up to 7 years it is recommended to use Enterofuryl suspension. The duration of therapy, as well as the dosage in a specific clinical situation, is determined by the doctor.
The dosage of the drug for adult patients is 200 mg (contained in one scoop) four times a day. The maximum daily dosage is 800 mg. The recommended course of treatment is 7 days.
In patients aged 2-7 years, the dosage is 200 mg (measuring spoon) three times a day. The maximum daily dosage is 600 mg. The duration of therapy is no more than a week.
In patients aged 7 months - 2 years, the dosage is 100 mg (contained in half a measuring spoon) three times a day. The maximum daily dosage is 400 mg. Duration of use of Enterofuryl should not exceed 7 days.
In children from 1 to 7 months, the dosage is 100 mg twice a day.
Enterofuryl is used regardless of the diet. The capsule should be swallowed whole, washed down with plenty of water. It is not recommended to divide the capsule. The suspension must be shaken thoroughly before use. For convenience, it is recommended to use the supplied measuring spoon.

Side effect

The drug is usually well tolerated, as evidenced by reviews of the drug from patients. In isolated cases, the appearance of an allergic reaction in the form of urticaria was noted.

During pregnancy

According to strict indications, the drug can be prescribed during pregnancy, but only in situations where the expected benefit to the mother's body significantly exceeds the potential threat to the fetus. There is currently no data on the negative effect of Enterofuryl on the fetus. Enterofuryl does not pass into breast milk, therefore, it can be prescribed during lactation.

Interaction with other drugs

Due to the lack of absorption, the interaction of Enterofuryl with other drugs is unlikely. However, the use of the drug with drugs containing ethyl alcohol is not recommended. Enterofuryl cannot be used simultaneously with sorbents, in this case its effectiveness decreases.

Overdose

There is no information about an overdose of the drug. In case of accidental intake of very high doses of the drug, non-specific therapy is recommended: gastric lavage, oral enterosorbents.

Reviews

The effectiveness of the drug and analogues has been proven in many clinical trials. The drug has proven itself well in the treatment of infectious pathology of the gastrointestinal tract, so the reviews about the drug are positive. The drug is relatively safe, in most cases it is well tolerated.

Storage conditions

It is recommended to store the drug at room temperature.

Terms of sell

You don't need a prescription from a doctor to buy Enterofuryl.