Cerucal injections 5mg/ml 2ml #10

Instruction for Cerucal injections

You can buy Cerucal injections here

Vomiting, especially severe and prolonged vomiting, is very unpleasant, but antiemetics such as Cerucal injections can effectively block the symptom. The drug is safe and effective, it can be prescribed to reduce the intensity or suppress the gag reflex in adults and children.
In the instructions for use, "Cerucal" injections is presented as an effective antiemetic agent that eliminates nausea and stops or reduces the frequency of vomiting in patients of different age categories due to the effect on the brain structures of the head and peripheral nerve endings. "Cerucal" simultaneously functions as a medication for hiccups and prokinetic, which increases the intensity of food movement along the gastrointestinal tract.
How long does the "Cerucal" injection work in a child and an adult, we will describe below.

Characteristic

The main substance of the drug is metoclopramide. The mechanism of its functioning is based on the blocking of chemoreceptors in the medulla oblongata, as well as serotonin and dopamine receptors in the duodenum and stomach, thanks to which the digestive organs send signals to the brain.
Among other things, metoclopramide has an effect on the nervous autonomic system. Thanks to this effect, it can:
    to enhance the muscle tone of the intestines, stomach and lower esophageal sphincter;
    reduce motor esophageal activity;
    improve intestinal peristalsis;
    accelerate the movement of food along the digestive tract;
    facilitate the release of bile;
    reduce hiccups;
    reduce dyskinesia of the bile ducts and gallbladder;
    reduce hyperacid stasis;
    to weaken the spasm of the sphincter of Oddi, which is located in the area of ​​the exit of the bile duct into the duodenum.
Antiemetic injections "Cerucal" do not affect the production of enzymes of bile and pancreas, gastric juice in the human body.

Release form

The drug is available in two forms: solution for intramuscular / intravenous administration and tablets.
The dose of "Cerucal" in injections for children and adults, which is prescribed by the attending physician, must be strictly observed.
The solution is poured into 2 ml ampoules, which contain 10 mg of the active ingredient. Also available are tablets "Cerucal", which have a dosage of 10 mg. You can find on sale a similar product called "Metoclopramide".

Pharmacokinetic description

Many people wonder how long the "Cerucal" injection takes effect?
The drug, when taken orally, is almost completely absorbed into the blood, its content in the blood reaches its maximum in an hour. The therapeutic effect lasts for 12 hours. If the drug is injected intramuscularly, it starts to "work" after 15 minutes, with intravenous administration - within 1-3 minutes.

Indications for use

The scope of application of "Cerucal" injections is quite wide; it is not limited to the fight against vomiting alone. The tool is used in the following cases:
    hypotension and atony of the intestines and stomach, including postoperative;
    persistent hiccups or vomiting of various origins;
    reflux gastroesophageal disease;
    nausea of ​​various origins (gastrointestinal diseases, food poisoning);
    heartburn;
    diabetic gastric paresis;
    irritable bowel syndrome.
Intramuscularly "Cerucal" is also often used as an antiemetic drug when undergoing radiation therapy and the use of cytostatic agents. Medication for duodenal and gastric intubation helps to relax the muscles of the esophagus and stomach, which helps to facilitate the diagnostic procedure. Before X-ray examination, "Cerucal" can also be prescribed, since it allows you to quickly empty the stomach and remove its contents into the duodenum.
The drug is almost ineffective for vomiting, the causes of which are psychogenic and vestibular factors. Thus, this medication would be pointless to take for motion sickness syndrome.

Contraindications

"Cerucal" injections during pregnancy are contraindicated in women in the first trimester. In the remaining six months, it can be prescribed by a doctor if the benefits of its use outweigh the possible harm. The drug is not allowed to be prescribed during lactation, as it passes freely into breast milk. Pills are contraindicated for children under the age of 14, it is better for such patients to administer the drug by the parenteral method.
Contraindications also include:
    gastric pyloric stenosis;
    pheochromocytoma;
    bleeding of the stomach and intestines;
    intestinal obstruction;
    age up to two years;
    a history of seizures and epilepsy;
    perforation of the gastrointestinal tract.
Very carefully, the remedy is prescribed to people who suffer from arterial hypo- or hypertension, liver failure, Parkinson's disease, bronchial asthma, patients over 65 years of age. If kidney function is reduced, the drug is prescribed in a reduced amount.

Side effects

Nervous system: a feeling of fatigue, a feeling of fear, dizziness, anxiety, headaches, drowsiness, depression, tinnitus, sometimes (mainly in children) develops dyskinetic syndrome, that is, teak-like involuntary twitching of the muscles of the shoulders, neck or face.
Extrapyramidal disorders may appear: rhythmic protrusion of the tongue, spasm of the facial muscles, trismus, bulbar speech type, spasm of extraocular muscles (including oculogyric crisis), muscle hypertonicity, opisthotonus, spastic torticollis.
With prolonged treatment in some elderly patients, adolescents and children (if the dosage is exceeded 0.5 mg / kg per day), parkinsonism (limited mobility, muscle twitching, tremor) may develop. Elderly patients with chronic kidney failure are likely to develop tardive dyskinesia.
Also, in isolated situations, neuroleptic malignant syndrome can develop (characteristic symptoms: increased pressure, change in consciousness, muscle contracture, fever).
Hematopoietic system: agranulocytosis.
Cardiovascular system: increased or decreased pressure, supraventricular tachycardia.
Gastrointestinal tract: diarrhea, dry mouth, constipation.
Endocrine system: if the drug is used for a long time, in rare cases, gynecomastia may occur, that is, an increase in the mammary glands in men, galactorrhea (milk flow spontaneously from the mammary glands) or abnormalities in the menstrual cycle. If such phenomena develop, the drug should be canceled.
Due to possible undesirable effects caused by the nervous system, it is advisable to refuse to drive a car during use.

Interaction with other substances

Do not dilute ampoules with drugs with alkaline solutions. When a patient is being treated with paracetamol or antibiotics, according to the instructions for use, Cerucal injections will enhance the effect of the prescribed funds. Undesirable symptoms may develop, the liver will suffer from toxic effects.
When interacting with "Cimetidine" and "Digoxin" solution "Cerucal" for injection reduces the absorption of these drugs, reducing their therapeutic effect.
Injections simultaneously with the use of alcohol suppress the central nervous system, the speed of reactions slows down. Simultaneous administration with H2-histamine blockers should be avoided, since antihistamines are ineffective in this case.
When "Cerucal" injections interacts with hepatotoxic medications, the liver suffers. A significant toxic effect on the organ will cause serious consequences.
The patient can always refuse to use injections "Cerucal", since there are analogues in pharmacies with a similar effect. Before replacing the drug, you must consult with a specialist, and before use, be sure to read the instructions.

Instructions for use for injections "Cerucal"

When using injections, three injections are given per day, 2 ml each (for children from 14 years old and for adults). The solution is administered intravenously or intramuscularly. When choosing an intravenous route, the drug should be administered as slowly as possible to reduce the likelihood of side effects.
As indicated by the instructions for the use of "Cerucal" injections, for children, the dosage is calculated depending on body weight. Most often, they take 0.1 mg per kilogram of weight, the maximum dosage per day is 0.5 mg per kilogram.
If the patient is being prepared for the examination of the stomach, then one or two injections of "Cerucal" are made 10 minutes before the manipulation. When using cytostatics through a dropper, infusion is practiced. This procedure is done two hours before the use of cytostatics.
The dosage of "Cerucal" injections depends on a person's weight - from 0.5 to 1 mg per kilogram of body weight per hour. When a cytostatic was introduced, the agent is infused during the day at the rate of 0.25 to 0.5 mg of the agent per kilogram per hour.
Regardless of the method of administration of the drug, it is recommended to regularly change the area for injection. In order to dilute the agent in ampoules, the most optimal option is used - a glucose solution of 5% or sodium chloride. If an injection is made into a muscle, then the drug is not diluted with anything.
What else can you learn from the instructions for use for "Cerucal" injections?

Additional Notes

There are several things to look out for:
    There is the possibility of a less predictable reaction when using the medication in adolescence, which is why additional supervision of the attending physician is required in this case.
    During treatment, it is recommended to avoid activities that require concentration, for example, when driving, as emergency situations are possible.
    When it becomes necessary to replace the drug with an alternative agent, the attending physician in most cases will choose a solution of "Metoclopramide" or "Perinorm".
    In some situations, you need to deviate from the recommended dosages of "Cerucal" injections. The dosage is always assigned individually, for example, if a person has serious kidney or liver pathologies, then the standard dose will not be assigned to him.

Reviews of doctors

This remedy is often used by pregnant women. It is tried and true, it helps with the gag reflex. Patients in an interesting position are advised to take it before a dentist appointment, making the specialist's intervention more comfortable.
The drug has a minimal number of side effects, it acts quickly.
It is a good antiemetic and has a central effect. It relieves vomiting and nausea of ​​various origins, is easy to use due to the variety of release forms, and is used in pediatric practice.
The drug is well studied. Helps with severe nausea and vomiting, with various diseases of the gastrointestinal tract. Its cost is available to everyone. Can be administered intramuscularly if vomiting prevents the use of tablets.
The drug is not designed for long-term use.
Of the disadvantages, there is a decrease in appetite for a long period after injection.
When compared with modern antiemetics, then "Cerucal" injections has a lower efficiency.

Patient reviews

The drug is very effective in vomiting and nausea. Users claim that it saves them from motion sickness. The drug begins to function in 15 minutes and completely eliminates the feeling of nausea.
The drug helps with stomach problems when vomiting occurs due to the consumption of fatty or heavy foods. Thanks to the injection of the drug, vomiting quickly passes, the condition returns to normal after a while.
"Cerucal" injections fights toxicosis in pregnant women, helps them out in this difficult situation. That is why patients often recommend having the drug in their home medicine cabinet and advise their loved ones.
There are also negative reviews. So, for some patients, the drug did not help at all. For example, when severe nausea appeared after nervous stress, periodically appearing for two years, it was accompanied by chills and vomiting, doctors diagnosed GERD. Doctors injected with nausea exclusively "Tserukal". But for some patients, in this case, neither ampoules nor pills bring the desired result, while the nausea does not stop. In such a situation, everything indicates the individual insensitivity of the organism.
The disadvantage of the drug is strong side effects, so if you experience unwanted symptoms, you should consult your doctor.

Terms of sell

You can buy Cerucal injections without a prescription.