Stopgripan powder #10

Stopgripan instruction for use

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Release form and composition

Dosage form Stopgripan - powder for the preparation of a solution for oral administration, crystalline: lemon - light yellow, with a specific lemon flavor, the resulting solution is yellowish, opaque, has a lemon smell; blackcurrant - from light pink to dark pink with blue crystals, with a specific aroma of blackcurrant, the resulting solution is purple, opaque, has the smell of blackcurrant (in a cardboard box of 10 sachets of 21.5 g each).
Composition of Stopgripan (1 sachet):
    active substances: pheniramine maleate - 20 mg; phenylephrine hydrochloride - 10 mg; paracetamol - 325 mg; ascorbic acid - 50 mg;
    auxiliary components: maltodextrin, dihydrate sodium citrate, sucrose, ethyl maltol, titanium dioxide, calcium phosphate, malic acid, citric acid, dye, sunset yellow; lemon - lemon flavor, quinoline yellow dye; blackcurrant - blackcurrant flavor, Ponceau 4R dye, brilliant blue dye.

Pharmacodynamics

The action of Stopgripan is due to the properties of its active components:
    Pheniramine: has an anti-allergic and decongestant effect, helps to reduce vascular permeability, nasal discharge, lacrimation, as well as eliminate sneezing;
    phenylephrine: has a vasoconstrictor effect, which helps to eliminate swelling of the mucous membranes of the nose, sinuses and nasopharynx, reduce discharge from the nose and, as a result, facilitate nasal breathing;
    paracetamol: has analgesic and antipyretic properties;
    ascorbic acid: improves the tolerance of paracetamol and lengthens its effect; takes part in the regulation of carbohydrate metabolism, redox processes, blood coagulation, tissue regeneration, as well as in the synthesis of steroid hormones; increases the body's resistance to infections, reduces vascular permeability, the need for vitamins B1, B2, A, E, pantothenic and folic acid.

Indications for use

    colds, flu, sinusitis, rhinopharyngitis, acute rhinitis, inflammation of the paranasal sinuses, which are accompanied by chills, fever, runny nose, headache, sensation of nasal congestion;
    mild and moderate pain syndrome with arthralgia, myalgia, neuralgia, migraine, toothache and headache, pain with injuries, algomenorrhea.

Contraindications

Absolute:
    alcoholism;
    combined use with tricyclic antidepressants, monoamine oxidase inhibitors, beta-blockers, as well as drugs that contain the active components of Stopgripan;
    diabetes;
    portal hypertension;
    pregnancy and lactation;
    age up to 12 years;
    individual intolerance to the components of the drug.
Relative (Stopgripan is prescribed under medical supervision):
    glucose-6-phosphate dehydrogenase deficiency;
    arterial hypertension;
    congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes);
    blood diseases;
    angle-closure glaucoma;
    severe atherosclerosis of the coronary arteries;
    hepatic / renal failure;
    hyperthyroidism;
    prostate adenoma;
    bronchial asthma;
    pheochromocytoma.

Instructions for use Stopgripan: method and dosage

Stopgripan is taken orally.
First you need to pour the contents of 1 sachet into a glass, fill the glass with hot water, mix until completely dissolved.
Recommended application: 3-4 times a day (with interruptions of at least 6 hours), 1 sachet. Maximum - 4 sachets per day.
If after five days of therapy the symptoms of the disease do not go away, you should consult your doctor.

Side effects

If the dosing regimen is observed, Stopgripan is usually well tolerated. In some cases, the following adverse reactions may develop: dizziness, increased irritability, decreased rate of psychomotor reactions, increased blood pressure, allergic reactions (such as skin itching, rash, urticaria, angioedema), glucosuria, xerostomia, vomiting, nausea, epigastric pain areas, palpitations, sleep disturbance, renal colic, urinary retention, increased intraocular pressure, paresis of accommodation, mydriasis.
Stopgripan contains paracetamol, therefore, in rare cases, hematopoietic system disorders may develop (in the form of thrombocytopenia, leukopenia, agranulocytosis, hemolytic anemia, aplastic anemia); with a long course with high doses, violations of the kidney and liver function may occur.

Overdose

An overdose of Stopgripan may be due to paracetamol.
Possible symptoms: pallor of the skin, pain in the epigastric region, vomiting, nausea, anorexia; in severe cases - an increase in prothrombin time, liver failure, increased activity of hepatic transaminases, hepatonecrosis, coma and encephalopathy. A detailed clinical picture of liver damage manifests itself after 1-6 days. Hepatic failure rarely occurs at lightning speed, it can be complicated by renal failure (in the form of tubular necrosis).
Therapy: gastric lavage followed by the intake of activated carbon; symptomatic treatment; introduction after 8–9 hours after overdose of SH-group donors and precursors of glutathione synthesis - methionine, after 12 hours - N-acetylcysteine.

special instructions

To avoid toxic damage to the liver, Stopgripan should not be combined with alcoholic beverages.
If the condition worsens / does not improve during therapy, consult your doctor.

Influence on the ability to drive vehicles and complex mechanisms

Patients during Stopgripan therapy should refrain from driving.

Pregnancy and lactation

According to the instructions, Stopgripan is not prescribed during pregnancy / lactation.

Use in childhood

Stopgripan therapy is not prescribed for patients under 12 years of age.

In case of impaired renal function

Renal failure: the drug should be used under medical supervision.

With impaired liver function

Hepatic insufficiency: the drug should be used under medical supervision.

Drug interaction

    monoamine oxidase inhibitors, sedatives, ethanol: their effect is enhanced;
    phenothiazine derivatives, antidepressants, antipsychotic and antiparkinsonian drugs: the likelihood of xerostomia, constipation, urinary retention increases;
    glucocorticosteroids: the risk of increased intraocular pressure increases;
    indirect anticoagulants: their effectiveness increases (due to paracetamol);
    uricosuric preparations: their effectiveness is reduced (due to paracetamol);
    monoamine oxidase inhibitors, furazolidone: the likelihood of developing a hypertensive crisis, agitation, hyperpyrexia increases (due to pheniramine);
    tricyclic antidepressants: the sympathomimetic effect is enhanced;
    halotane: the risk of developing ventricular arrhythmias increases;
    guanethidine: its hypotensive effect increases, while the alpha-adrenostimulating activity of phenylephrine is enhanced;
    barbiturates, diphenin, carbamazepine, rifampicin and other inducers of microsomal liver enzymes: the likelihood of hepatotoxic effects of paracetamol increases.

Terms and conditions of storage

Store in a dry place at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.

Reviews

According to reviews, Stopgripan quickly relieves symptoms of the common cold and flu, such as a feeling of nasal congestion, chills, runny nose, and fever. They note its low cost among analogues and a pleasant aroma. Some patients do not like the overly pronounced taste of lemon. Among the shortcomings indicate the possibility of side effects, manifested mainly in the form of drowsiness.

Terms of sell

You don't need a prescription to buy Stopgripan.