Sinuforte 50mg

Instruction for Sinuforte

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Release form and composition

Dosage form - lyophilisate for the preparation of a solution for intranasal use: hygroscopic, from white to light brown; the prepared solution is from colorless to light yellow (50 mg each in colorless glass bottles, in a plastic tray 1 bottle complete with a nozzle-sprayer and 1 plastic bottle with a solvent, 1 tray in a cardboard pack).
Active substance: lyophilisate juice and extract of fresh tubers of European cyclamen (with hemolytic index 1: 6000–1: 12 000), in 1 bottle - 50 mg.
Solvent: water for injection (5 ml).

Pharmacodynamics

Sinuforte is a herbal preparation used for inflammatory diseases of the nasal cavity and paranasal sinuses. The mechanism of its action is due to the effect on the trigeminal nerve receptors located in the middle nasal passage. Due to this effect, reflex secretion in the mucous membrane of the nasal cavity and paranasal sinuses is caused. As a result of hypersecretion, the rheological properties of the secret change, and its viscosity normalizes.
Sinuforte also has a decongestant effect, which in combination with reflex hypersecretion leads to the release of secretions from the sinuses into the nasopharynx. This provides simultaneous drainage of all sinuses.
The drug restores mucociliary transport and enhances blood microcirculation in the paranasal sinuses and nasal cavity. The improvement in microcirculation is due to vasodilation of the vessels that supply the glands.
Hypersecretion in the form of serous-mucous secretions occurs a few minutes after the use of the drug and lasts 30-120 minutes, which depends on the individual characteristics of the patient.

Pharmacokinetics

The therapeutic effect of Sinuforte is due to the effects of the components that make up cyclamen. To date, the most studied of them are triterpene saponins.
Pharmacokinetic parameters of the drug have not been studied, since these components and their metabolites cannot be traced using markers or appropriate bioassays.

Indications for use

    acute and chronic sinusitis: frontal sinusitis, sinusitis, sphenoiditis, ethmoiditis (in the uncomplicated course of the disease - as monotherapy, in other cases - as part of complex therapy, with purulent sinusitis occurring with symptoms of orbital complications and / or generalization of the infection - in combination with antibiotics );
    rhinosinusitis accompanied by exudative otitis media (as part of complex therapy);
    the period of early rehabilitation after endoscopic surgery on the paranasal sinuses.

Contraindications

    cysts of the paranasal sinuses;
    polypous rhinosinusitis;
    allergic rhinosinusopathies;
    arterial hypertension II and III art .;
    delayed and immediate allergic reactions;
    children under 5 years old;
    period of pregnancy and lactation;
    hypersensitivity to the components of the drug.

Instructions for use Sinuforte: method and dosage

Sinuforte is intended for intranasal administration.
Rules for the use of the drug:
    Unscrew the cap from the vial with lyophilisate, remove the cork.
    Open the solvent bottle by breaking off the top.
    Pour solvent into vial with lyophilisate.
    Screw on spray nozzle.
    Shake the drug until the lyophilisate is completely dissolved.
    Remove the protective cap from the spray gun.
    Perform 2-3 test sprays into the air.
    Keeping your head upright, insert the nebulizer into the nasal passage, hold your breath and spray with one click. Repeat with the second nostril.
One click on the nozzle-sprayer (one dose) corresponds to 2-3 drops of a solution (0.13 ml), or 1.3 mg of the drug.
Adults and children over 5 years of age are prescribed 1 dose 1 time per day in each nasal passage daily or every other day.
The duration of treatment with daily use of Sinuforte is 6-8 days, when administered every other day - 12-16 days.

Side effects

    a feeling of mild or moderate burning in the nasal cavity, lacrimation and / or salivation;
    allergic reactions (including skin rashes, shortness of breath).
In some cases, possible: short headache in the frontal part, redness of the face, the appearance of a pale pink colored discharge from the nose due to capillary diapedesis. These reactions are short-term in nature and do not require discontinuation of treatment.

Overdose

Cases of overdose Sinuforte not registered. If a single dose of the drug is exceeded, the therapeutic effect does not increase, but pain and a burning sensation in the nasopharynx are possible.
Symptomatic treatment: washing the nasal cavity and throat with warm water, the use of antihistamines.

special instructions

Before using Sinuforte, it is recommended to consult with an ENT doctor.
With the introduction of the drug, caution should be exercised and avoid contact with eyes, since this is fraught with the development of acute conjunctivitis.
In the period of postoperative rehabilitation after endoscopic interventions, Sinuforte is used on the second day to reduce swelling of the mucous membrane and sanitation (cleansing) of the paranasal sinuses and nasal cavity.

Pregnancy and lactation

Sinuforte is contraindicated in pregnant women. If you need to use the drug during lactation, breastfeeding should be temporarily discontinued.

Use in childhood

According to the instructions, Sinuforte is not used in children under 5 years old.

Drug interaction

If necessary, Sinuforte can be prescribed in combination with antibiotics.
Local anesthetics and / or local decongestants should not be used previously and simultaneously, as they may interfere with the mechanism of action of Sinuforte.
Possible interactions with other drugs have not been studied to date.

Terms and conditions of storage

Keep out of the reach of children, protected from light at temperatures up to 25 ° C.
Shelf life is 5 years.
The prepared solution can be stored for no more than 15 days in a dark place at a temperature of 2–8 ºС.

Reviews about Sinuforte

According to reviews, Sinuforte is a really effective remedy for acute and chronic inflammatory diseases of the nasal cavity and paranasal sinuses. Patients note that the drug perfectly treats sinusitis, relief comes within a few days. As a result of the use of Sinuforte, the sinuses are cleaned naturally, which helps to avoid punctures.
The drug is natural and non-addictive. Despite the relatively high cost, Sinuforte is popular with patients. The drug fully justifies its price. Some patients complain of a burning sensation that occurs when instilling a solution, but in general there are significantly fewer negative reviews about Sinuforte than positive ones.

Terms of sell

You don't need a prescription to buy Sinuforte.